Clinical trials: Palliative Cancer
Lung Cancer
Palliative Care Teaching Sessions for Family Caregivers of Patients With Non-Small Cell Lung Cancer
RATIONALE: Palliative care teaching sessions may be more effective than standard care in improving caregiver burden, caregiver skills preparedness, quality of life, and distress in family caregivers of patients with non-small…
- Trial name
- NCT00827333
- Testing
- educational intervention, questionnaire administration, end-of-life treatment/management
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- City of Hope Medical Center
Gynecologic Cancer
The HOPE Trial and the SMART Study
This research study is evaluating a new smartphone application named the "Helping Our Patients Excel (HOPE)" app with a Fitbit device. The SMART Study is a sub-study of the HOPE Trial.
- Trial name
- NCT03022032
- Testing
- Fitbit Zip, HOPE App, Standard of Care
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Dana-Farber Cancer Institute
Colorectal Neoplasms
Study to Evaluate the Effects of Sorafenib if Combined With Chemotherapy (FOLFOX6 or FOLFIRI) in the Second-Line Treatment of Colorectal Cancer
The purpose of this study is to determine whether sorafenib in combination with chemotherapy has a positive effect on time to progression of the tumor or death for the treatment of large bowel cancer that has already progressed…
- Trial name
- FOSCO (NCT00889343)
- Testing
- Sorafenib, Oxaliplatin or Irinotecan, Leucovorin
- Where
- 57 sites in Germany
- Volunteers
- 101 people
- Sponsor
- AIO-Studien-gGmbH
Bone Metastases
Lazanda in Cancer Patients Receiving Palliative Radiation
Advanced cancer patients often require palliative (pain relieving) radiotherapy to treat cancer-related symptoms. The delivery of radiation requires patients to lie still on a hard flat surface, which can result in significant…
- Trial name
- NCT03071744
- Testing
- Lazanda
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Joseph Ma
Liver Cancer, Anxiety Disorder
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
The study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and non-colorectal gastrointestinal malignancies who are…
- Conditions
- Liver Cancer, Anxiety Disorder, Depression, Small Cell Lung Cancer
- Trial name
- NCT02349412
- Testing
- Early palliative care
- Where
- 23 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Cancer, Kidney Diseases
Patient Reported Unmet Needs for Function and Supportive Occupational- and Physiotherapy Rehabilitation Interventions
Purpose: To determine unmet functional needs in patients referred to the Palliative Care Unit at Rigshospitalet, Copenhagen University Hospital will be asked to fill out self reported questionnaires regarding problem intensity…
- Conditions
- Cancer, Kidney Diseases, Heart Failure, Neurologic Disorder
- Trial name
- NCT04066153
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer
Behavioral Pain Intervention for Older Cancer Patients
This randomized controlled trial examines a 1-session, telehealth pain coping skills training (PCST) protocol with five 15-minute maintenance calls (Brief PCST-Community) adapted for women with breast cancer in medically…
- Trial name
- NCT07300995
- Testing
- Pain Coping Skills Training (PCST)
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Weill Medical College of Cornell University
Cancer
Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients
RATIONALE: Palliative care may help patients with advanced cancer live more comfortably. PURPOSE: This randomized clinical trial is studying an early intervention palliative care program to see how well it works compared to a…
- Trial name
- NCT00253383
- Testing
- counseling intervention, educational intervention, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer
Good Choice of pALliative Chemotherapy to Patient With Pancreatic Cancer ; GemcitAbine Therapy vs FOLFORINOX therapY
The study objectives are to find out: 1) palliative chemotherapy patterns and prognosis in patients with locally advanced or metastatic pancreatic cancer in Korea's real clinical settings, and 2) reasons adopted by clinicians in…
- Trial name
- GALAXY (NCT04789980)
- Where
- South Korea
- Volunteers
- 799 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hematologic Neoplasms
Early Palliative Care and Hematological Cancer Patients
The aim of the study is to pilot and evaluate a new integration model between a Specialised Palliative Care (SPC) intervention and standard hematological care in an Italian hospital.
- Trial name
- EPC-EMA1 (NCT03743480)
- Testing
- early palliative care
- Where
- 2 sites in Italy
- Volunteers
- 15 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Lung Cancer, Nonsmall Cell, Stage IIIA, Lung Cancer Non-Small Cell Stage IIIB
Psychosocial eHealth in Advanced Lung Cancer
Being diagnosed with cancer impairs many areas of a person's life. Although efficacious educational, emotional and social interventions exist in this regard, they often reach few survivors and late.
- Conditions
- Lung Cancer, Nonsmall Cell, Stage IIIA, Lung Cancer Non-Small Cell Stage IIIB, Lung Cancer Non-Small Cell Stage III, Lung Cancer Stage IV
- Trial name
- NCT05497973
- Testing
- E-health ecosystem of stepped psychosocial care, Usual psychosocial care
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Institut Català d'Oncologia
Fatigue
Improving Symptom Management for Cancer Patients and Their Caregivers Through Internet
Being diagnosed and treated for cancer is usually associated with severe side effects and symptoms. Cancer patients can have difficulty to manage the symptoms as a result of treatment which may cause i) an interruption or…
- Trial name
- NCT01867723
- Testing
- Internet communication application
- Where
- Norway
- Volunteers
- 560 people
- Sponsor
- Oslo University Hospital
Gastric Cancer
Electrochemotherapy for Non-curable Gastric Cancer
This is an explorative, phase I clinical trial. The aim of this study is to establish the safety and efficacy of electrochemotherapy for non-curable gastric cancer.
- Trial name
- NCT04139070
- Testing
- Bleomycin
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Zealand University Hospital
Solid Tumors
M3541 in Combination With Radiotherapy in Solid Tumors
This dose-escalation study evaluated the safety, tolerability, pharmacokinetic (PK), pharmacodynamic, and explore antitumor activity of M3541 in combination with fractionated palliative radiotherapy (RT) in participants with…
- Trial name
- NCT03225105
- Testing
- M3541, Palliative Radiotherapy (RT)
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Malignant Neoplasm, Metastatic Malignant Neoplasm in the Bone
Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
This randomized phase II trial studies how well palliative radiation therapy works in reducing pain in patients with cancer that has spread from the original (primary) tumor to the bone (bone metastasis).
- Conditions
- Malignant Neoplasm, Metastatic Malignant Neoplasm in the Bone, Pain
- Trial name
- NCT02699697
- Testing
- External Beam Radiation Therapy, Palliative Radiation Therapy, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Wake Forest University Health Sciences
COPD, Heart Failure
Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness
The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting…
- Conditions
- COPD, Heart Failure, Cancer
- Trial name
- NCT03391115
- Testing
- Storytelling Intervention for Patient Participants, Storytelling Intervention for Nurse Participants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Bone Metastases, Bone Neoplasm
Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis
The PRE-FURTHER study aims to evaluate the feasibility of the combined treatment with radiotherapy and focussed ultrasound for pain palliation in patients with painful bone metastases, and to optimize the combined treatment…
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
- Trial name
- PRE-FURTHER (NCT04310410)
- Testing
- combined radiotherapy and MR-HIFU
- Where
- 2 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- UMC Utrecht
Adenocarcinoma of the Esophago-gastric Junction
Comparison Study of Brachytherapy and Endoscopic Stenting for Dysphagia in Esophago-Gastric Junction Cancer
The objective of the study is comparison of the efficacy and safety of palliative therapy with single-dose brachytherapy or selfexpanding metal stents (SEMS) in malignant dysphagia resulting from adenocarcinoma of the…
- Trial name
- BRASTEGAC (NCT01786278)
- Testing
- Brachytherapy, Endoscopic stenting
- Where
- 2 sites in Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Lublin
Pain, Nausea
Cannabis For Cancer-Related Symptoms
Clinical evidence is urgently needed to be able to advise patients on which cannabis-based products to take, or to avoid, in managing cancer-related symptoms.
- Conditions
- Pain, Nausea, Anxiety, Sleep Disturbance
- Trial name
- CAFCARS (NCT03948074)
- Testing
- Cannabis
- Where
- 8 sites in Canada
- Volunteers
- 91 people
- Sponsor
- Pippa Hawley
Cancer, Cancer Survivors
Symptom Management for Rural-Urban Cancer Survivors and Caregivers
As the population of cancer survivors increases substantially, meeting the health care and psychosocial needs of this population has become a national priority.
- Conditions
- Cancer, Cancer Survivors, Informal Caregivers, Psychological Distress
- Trial name
- NCT05360498
- Testing
- Adaptive Symptom Management and Survivorship Handbook (SMSH) and Telephone Interpersonal Counseling (TIP-C), NCI Brochure
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- University of Arizona
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