Clinical trials: Palliative Cancer
Symptom Management, Young Adult Cancer
Reducing Health Disparity of Physical Functioning Among Young Adult Cancer Patients of Color
The purpose of the study is to pilot test of PAfitME™ among (1) young adults (YA) cancer patients of color (POC) (Analytic Sample [N=36] after attrition of 30%) and (2) YA cancer patients of White (POW) (Analytic Sample [N=36]…
- Conditions
- Symptom Management, Young Adult Cancer, Physical Activity, Gaming
- Trial name
- NCT07715344
- Testing
- PAfitME™
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Alabama at Birmingham
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Cancer, Palliative Radiotherapy
Palliative Lattice Stereotactic Body Radiotherapy (SBRT)
Standard palliative radiotherapy regimens may provide limited durability of response in large tumors. Thus, there is a clinical need for a new approach.
- Trial name
- NCT04133415
- Testing
- Lattice stereotactic body radiation therapy, Peripheral blood
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Pain
Efficacy of Low Analgesic Doses of Ketamine Associated With Opioids in Refractory Cancer Pain Treatment
Long-term opioid therapy is commonly administered for the management of severe cancer pain. Increasing doses of opioids are titrated against effects until analgesia is achieved or intolerable adverse effects occur.
- Trial name
- KEPAL (NCT01326325)
- Testing
- Ketamine, NaCl
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Palliative Care, Diabetes Mellitus, Type 2
GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients.
Cancer patients with known or newly diagnosed (i.e. iatrogenic) Diabetes Mellitus (DM) in Palliative/Supportive Care will be enrolled. Patients will be randomly assigned to one of two groups.
- Conditions
- Palliative Care, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Diabetes
- Trial name
- NCT04942756
- Testing
- Continuous Glucose Monitoring, Standard Care
- Where
- 6 sites in Israel, Italy and 1 more
- Volunteers
- 118 people
- Sponsor
- Antea Foundation
Malignant Neoplasm, Carcinoma
Short-term Psychodynamic Psychotherapy in Serious Physical Illness
Life-threatening physical illness may powerfully re-activate existential conflict. There is little evidence to date on the effectiveness of relationship-focused therapies in this patient group.The aim of this study is to pilot a…
- Conditions
- Malignant Neoplasm, Carcinoma, Palliative Care
- Trial name
- ORPHYS (NCT05520281)
- Testing
- Short-term psychodynamic psychotherapy for patients with serious physical illness (ORPHYS)
- Where
- 4 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stem Cell Transplant
In Person and mHealth Coping Skills Training for Symptom Management and Steps in Stem Cell Transplant Patients
Hematopoietic stem cell transplant (HCT) is an aggressive treatment for life-threatening cancers. HCT improves survival, but most HCT patients experience significant physical disability, which is exacerbated by persistent…
- Trial name
- Symptoms-Steps (NCT03859765)
- Testing
- HCT Symptoms and Steps
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Palliative Care Perception
Prospective Study of the Perception of Palliative Care by Relatives of Patients Treated in Oncology
The purpose of this study is to evaluate (thanks to analysed interview) the perception of palliative care by relatives of patients treated in oncology.
- Trial name
- NCT01936428
- Testing
- interview
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Uterine Cervical Neoplasms
Trial of TP Versus TC Regimens for Stage IVb, Persistent, or Recurrent Cervical Cancer (JCOG0505, CC-TPTC-P3)
To evaluate the clinical benefits of Paclitaxel plus Carboplatin compared with Paclitaxel plus Cisplatin in Stage IVb, Persistent, or Recurrent Cervical Cancer
- Trial name
- NCT00295789
- Testing
- chemotherapy: Paclitaxel/Cisplatin, chemotherapy: Paclitaxel/Carboplatin
- Where
- 30 sites in Japan
- Volunteers
- 253 people
- Sponsor
- Haruhiko Fukuda
Advanced Cancers
Occupational Therapy in Palliative Care
The goal of this research study is to learn if inpatient occupational therapy can help patients in the Palliative Care Unit (PCU).
- Trial name
- NCT02521194
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- M.D. Anderson Cancer Center
Advanced Head and Neck Cancer
Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer
This study is being done to answer the following question: Does stereotactic body radiation therapy (SBRT) provide better cancer control compared to standard radiation therapy (RT) for those with advanced head and neck cancer?
- Trial name
- NCT06641791
- Testing
- Standard Radiotherapy (SRT), Stereotactic Body Radiotherapy (SBRT)
- Where
- 10 sites in Canada
- Volunteers
- 196 people
- Sponsor
- Canadian Cancer Trials Group
Cancer
Pain, Anxiety of Aromatherapy and Music Effect on
The research is planned as a randomized controlled trial. The main question[s] it aims to answer are: [question 1]: Does the inhaler effect of music and aromatherapy applied to palliative care patients have an effect on pain…
- Trial name
- Palliative (NCT06024954)
- Testing
- aromatherapy, music therapy, aromatherapy and music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ege University
Carcinoma, Therapy
Coriolus Versicolor as Palliative Therapy Compared to Placebo in Patients With Child-Pugh C Unresectable Hepatocellular Carcinoma
The hypothesis of this study is that the median time to progression in the experimental arm is 2 months as compared to the placebo arm of 1.4 months
- Trial name
- NCT01097083
- Testing
- Coriolus Versicolor
- Where
- 3 sites in Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
Advanced Breast Cancer
Acceptability and Feasibility of PSC Model of Serious Illness Communication
This prospective, single-arm pilot study evaluates the feasibility and acceptability of a novel Patient Support Coordinator (PSC) model for women with advanced or high-risk breast cancer in an outpatient oncology setting.
- Trial name
- NCT07428655
- Testing
- PSC-facilitated supportive listening
- Where
- Singapore
- Volunteers
- 28 people
- Sponsor
- National Cancer Centre, Singapore
Cancer, Cancer Cachexia
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular…
- Conditions
- Cancer, Cancer Cachexia, Inflammation
- Trial name
- PROTECT (NCT04065815)
- Testing
- Resistance Training, WB-EMS, High-intensity interval training (HIIT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Symptom Management, Reduce Treatment Non-adherence
Project Persist: mHealth for Cancer Survivorship
Many studies have shown that anxiety and depression are associated with reduced treatment adherence and poor treatment outcomes among patients undergoing cancer treatments.
- Trial name
- Persist (NCT04126642)
- Testing
- Assessment only group, Intervention group
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Oklahoma
Congestive Heart Failure, Metastatic Cancer
Advance Care Planning in the Emergency Department
This is a two-armed, parallel-design, pre-/post-intervention assessment study. The investigators will conduct a randomized controlled trial for ED GOAL on a cohort of 120 older adults with serious illness to collect…
- Conditions
- Congestive Heart Failure, Metastatic Cancer, Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05209880
- Testing
- ED GOAL
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Brigham and Women's Hospital
Pancreas Cancer, Non-Resectable Pancreas Carcinoma
Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer
The aim of the study is to compare the efficacy and toxicity of full-dose Gemcitabine and reduced-dose combination chemotherapy in patients with non-resectable pancreatic cancer, who are unfit for full-dose combination…
- Trial name
- NCT05841420
- Testing
- Gemcitabine, Nab paclitaxel
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Morten Ladekarl
Advanced Prostate Cancer, Lower Urinary Tract Symptoms
TUPKRP Combined With MAB Therapy for LUTS/PCa
Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide, accounting for 15% of all male cancers. In 2015, there were 220,800 estimated new cases of prostate cancer and 27,540 deaths by PCa, making…
- Conditions
- Advanced Prostate Cancer, Lower Urinary Tract Symptoms, Quality of Life, Overall Survival
- Trial name
- NCT03701659
- Testing
- Surgery combinate with Endocrine therapy, Endocrine therapy
- Volunteers
- 100 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Malignant Glioma of Brain, Glioblastoma
LITT Palliative Treatment for Patients With Malignant Gliomas
The purpose of this study is to to describe the effect of a palliative regimen consisting of Laser Interstitial Thermal Therapy (LITT) on distress, quality of life (QOL), neurocognition, days in the hospital, patient disposition…
- Trial name
- NCT03176160
- Testing
- Palliative regimen consisting of LITT
- Where
- United States
- Sponsor
- Duke University
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