Clinical trials: Palliative Cancer
Colorectal Cancer, Bladder Cancer
Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)
This is a proof-of-concept pilot randomized clinical trial to test the feasibility of the innovative Patient-Reported Outcomes-Informed Symptom Management System (PRISMS) to enhance personalized supportive care for cancer…
- Conditions
- Colorectal Cancer, Bladder Cancer, Ovarian Cancer, Cervical Cancer
- Trial name
- PRISMS (NCT04492007)
- Testing
- Patient-Reported Outcomes-Informed Symptom Management System (PRISMS)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Neoplasms
A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer
This protocol will evaluate the activity of 5-Fluorouracil (FUra) given as a 1 hour infusion in combination with leucovorin (LV) and interferon IFN alpha-2a in patients with advanced, measurable colorectal cancer.
- Trial name
- NCT00001428
- Testing
- 5-fluorouracil
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Cancer Institute (NCI)
Carcinoma Breast Stage IV
Palliative Hypofractionated Radiotherapy in Advanced Incurable Breast Cancer
This prospective phase I/II study to assess the clinical toxicity and investigate the clinical response of breast cancers to a 10 fraction hypofractionated course of radiation therapy in advanced incurable breast cancer patients.
- Trial name
- HYPORT (NCT03511781)
- Testing
- Hypofractionated Radiotherapy
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Tata Medical Center
Head Neck Cancer, Squamous Cell Cancer of Head and Neck (SCCHN)
Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy
This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer and…
- Conditions
- Head Neck Cancer, Squamous Cell Cancer of Head and Neck (SCCHN), Cancer Pain
- Trial name
- MRg-FUS (NCT07405645)
- Testing
- ExAblate Neuro
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Leukemia, Acute, AML, Adult
Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDS
The purpose of this study is to estimate the potential benefit of early and continued palliative care (PC) consultation on end of life issues.
- Conditions
- Leukemia, Acute, AML, Adult, ALL, Adult, Myelodysplastic Syndromes
- Trial name
- NCT04482894
- Testing
- Palliative Care Visits
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Virginia
Palliative Care
With Love: Using Promotoras for a Hispanic Community Palliative Care Promotora Palliative Care
Despite being strongly recommended, the integration of palliative care in oncology has not been widely adopted. Very few people have access to comprehensive palliative care. Access is even lower in rural and Hispanic communities.
- Trial name
- NCT03736031
- Testing
- Intervention (Promotora)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Esophageal Cancer
Salvage Chemoradiation Therapy for Recurrence After Radical Surgery or Palliative Surgery in Esophageal Cancer Patients
Currently, adjuvant therapy is not recommended for patients with esophageal squamous cell carcinoma who received radical surgery.
- Trial name
- NCT03731442
- Testing
- Involved field irradiation, Elective field irradiation, Paclitaxel
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese Academy of Medical Sciences
Cancer, Advanced Solid Tumors, Malnutrition
A Nutrition and Exercise Program With Olanzapine Compared to Olanzapine Alone: A Trial in Patients With Advanced Tumors
Cancer patients have a higher risk of malnutrition because of their illness and treatments. This can lead to weight loss, weak muscles, less effective cancer therapy, or stronger side effects.
- Trial name
- SwissNutriAct2 (NCT07722806)
- Testing
- Standardized nutritional program, standardized exercize program, Whey protein supplement with added leucine and β-hydroxy-β-methylbutyrate (HMB)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Kantonsspital Winterthur KSW
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm
- Trial name
- PICSI-H (NCT04281784)
- Testing
- EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 2,512 people
- Sponsor
- University of Washington
Relapsed Adult AML, Primary Refractory Acute Myeloid Leukemia
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute…
- Conditions
- Relapsed Adult AML, Primary Refractory Acute Myeloid Leukemia, High Risk Acute Myeloid Leukemia
- Trial name
- SCOPE-L (NCT05237258)
- Testing
- Specialty Palliative Care, Primary Palliative Care
- Where
- 20 sites in United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Palliative Care, Constipation
Cross Sectional Study of Constipation in Advanced Cancer Patients
Constipation is a common problem in palliative cancer patients. However, there were insufficient randomized controlled trial (RCT) data to identify the "best" laxative or combination of laxatives in these patients.
- Conditions
- Palliative Care, Constipation, Traditional Chinese Medicine
- Trial name
- NCT01399294
- Where
- 2 sites in China
- Volunteers
- 255 people
- Sponsor
- Yan Chai Hospital
Metastatic Colorectal Cancer
Physical Activity in Patients With Metastatic Colorectal Cancer Who Receive Palliative First-line Chemotherapy
The purpose of this study is to assess whether a structured physical activity program (PA) during palliative chemotherapy improves progression-free survival (PFS) and/or patient-reported outcomes (ESAS-r) in patients with…
- Trial name
- NCT02597075
- Testing
- standard therapy + physical activity program, standard therapy
- Where
- 24 sites in Austria, Switzerland
- Volunteers
- 100 people
- Sponsor
- Swiss Cancer Institute
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Malignant Neoplasms of Independent (Primary) Multiple Sites
Difference in the Estimation of Prognosis
Objectives: Primary Objective: The primary objective is to identify the difference in the estimation of prognosis of advanced cancer patients between medical oncologists, gynecological oncologists, and palliative care physicians
- Trial name
- NCT03115528
- Testing
- Estimation of Prognosis Questionnaire
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gynecologic Cancer, Gastrointestinal Cancer
BOLSTER: Building Out Lifelines for Safety, Trust, Empowerment and Renewal
This research study is evaluating a new intervention, BOLSTER, which was designed to provide more support for patients with gynecologic and gastrointestinal cancers and their caregivers after a hospitalization.
- Trial name
- NCT03367247
- Testing
- BOLSTER, Enhanced Discharge Planning (EDP)
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Dana-Farber Cancer Institute
Stomach Neoplasms, Gastric Outlet Obstruction
Malignant Gastric Outlet Obstruction Study With Stomach Partitioning (GO-PART)
The goal of this clinical trial is to evaluate whether stomach-partitioning gastrojejunostomy (SPGJ) more effectively reduces postoperative delayed gastric emptying (DGE) compared to conventional gastrojejunostomy (CGJ) in…
- Trial name
- GO-PART (NCT07749326)
- Testing
- Conventional Gastrojejunostomy, Stomach-Partitioning
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Gyeongsang National University Hospital
Family, End of Life
Web-based Support for Family Caregivers of Patients With Advanced Cancer
For family caregivers of patients with advanced cancer, preparedness for caregiving is crucial for maintaining health and quality of life both during care and after the death of the patient.
- Conditions
- Family, End of Life, Cancer Metastatic, Chronic Illness
- Trial name
- NCT05785494
- Testing
- Narstaende.se
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Ersta Sköndal University College
Child, Only, Cancer
Digital Storytelling in Symptom Management Pediatric Oncology
The aim of this clinical study is to evaluate the effectiveness of the digital storytelling method in symptom management in children diagnosed with oncology.
- Conditions
- Child, Only, Cancer, Symptoms and Signs, Narration
- Trial name
- NCT06436651
- Testing
- Digital Storytelling
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kocaeli University
Colorectal Cancer, Nursing
The Effect of a Mobile Application on Patient Outcomes in Colorectal Cancer Patients
The aim of this study is to determine the effect of the interactive nurse support program developed as a mobile application on patient outcomes (symptom management, quality of life, perception of social support and anxiety) in…
- Trial name
- NCT05813028
- Testing
- a Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara University
Neoplasm Metastasis, Palliative Care
A Study Of Tanezumab as Add-On Therapy to Opioid Medication In Patients With Pain Due To Cancer That Has Spread To Bone
The purpose of this study is to investigate the safety and efficacy of tanezumab in combination with opioids in treating pain due to cancer that has spread to bone.
- Trial name
- NCT00545129
- Testing
- Tanezumab 10 mg IV
- Where
- 39 sites in United States, Austria and 11 more
- Volunteers
- 59 people
- Sponsor
- Pfizer
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.