Clinical trials: Palliative Cancer
Glioblastoma, Recurrent Brain Neoplasm
Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme
This pilot clinical trial studies the feasibility of palliative 4pi radiotherapy in treating patients with glioblastoma multiforme that has come back after standard chemoradiation.
- Trial name
- NCT02575027
- Testing
- Palliative Radiation Therapy, Questionnaire Administration, Radiation Therapy Treatment Planning and Simulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Asthenia, Neoplasms
Ritalin: Antiasthenic Effect of Methylphenidate (Ritalin) in Palliative Care in Cancer Patients
The aim/objective of this study is to evaluate the antiasthenic effect of methylphenidate with a visual analogical scale (VAS) after 7 days of treatment, in cancer patients, in palliative care, i.e.
- Trial name
- Ritaline (NCT00273741)
- Testing
- methylphenidate
- Where
- 13 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Grenoble
Cancer, Heart Failure
Implementing Spiritual Care in Inpatient Palliative Care
The goal of this observational study is to is to ascertain the spiritual needs of palliative patients in a standardized manner using the Spiritual Needs Questionnaire and to promptly address those needs by (specialized) spiritual…
- Conditions
- Cancer, Heart Failure, Chronic Obstructive Pulmonary Disease, Lateral Sclerosis
- Trial name
- SCPC (NCT06206551)
- Testing
- Spiritual Needs Questionnaire
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Metastatic Cancer, Prostate Cancer
Strontium Compared With Radiation Therapy in Treating Patients With Hormone-Refractory Prostate Cancer With Painful Bone Metastases
RATIONALE: Radiolabeled monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. This may be an effective treatment for prostate cancer.
- Trial name
- NCT00002503
- Testing
- strontium chloride Sr 89
- Where
- 21 sites in Belgium, Denmark and 7 more
- Volunteers
- 204 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Neoplasms, Oncology
An Observational Study of the Prevalence of Patients Requiring Palliative Care in French Anti-cancer Centers.
The purpose of this observational study is to determine the proportion of patients with a score greater than 3/10 to the questionnaire PALLIA-10.
- Trial name
- PREPA-10 (NCT02479061)
- Where
- 15 sites in France
- Volunteers
- 846 people
- Sponsor
- Centre Leon Berard
Melanoma
Pilot Ipilimumab in Stage IV Melanoma Receiving Palliative Radiation Therapy
To determine the safety of local palliative radiation therapy used in combination with anti-CTLA-4 immunotherapy.
- Trial name
- NCT01449279
- Testing
- Ipilimumab, Radiation Therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Biliary Cancer
Covered Versus Uncovered SEMS for Palliation of Malignant Biliary Strictures.
The purpose of this study is to compare the duration of stent patency of a covered vs. an uncovered biliary self-expandable metal stents (SEMS) placed to relieve biliary obstruction in patients with inoperable extrahepatic…
- Trial name
- SEMS (NCT02930252)
- Testing
- Niti-S Biliary ComVi Stent, Niti-S stent (D type)
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Azienda USL 1 Imperiese
Non-small Cell Lung Cancer, Gastric Cancer
Early Palliative Care on Quality of Life of Advanced Cancer Patients
This study compares two types of care - Standard Oncology Care (SOC) and SOC with early palliative care (EPC) (started within 8 weeks after diagnosis of advanced disease) to see which is better for improving the quality of life…
- Conditions
- Non-small Cell Lung Cancer, Gastric Cancer, Pancreatic Cancer, Biliary Tract Cancer
- Trial name
- NCT02988635
- Testing
- Early Palliative Care
- Volunteers
- 281 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Neoplasms
The Orkdal Model. Collaboration Between Specialist and Community Care Within Palliative Cancer Care
The overall aim of this project is to deliver better health care services through improved coordination of cancer care within specialist care (at the local hospital Orkdal Hospital) and community care (13 municipalities in the…
- Trial name
- NCT02170168
- Testing
- integrated palliative care program
- Where
- 25 sites in Norway
- Volunteers
- 969 people
- Sponsor
- St. Olavs Hospital
Lung Cancer - Non Small Cell, Lung Cancer (NSCLC)
Standard Care With or Without Early Palliative Care Provided by Palliative Care Specialist in Advanced Non-small Cell Lung Cancer Patients
Early palliative care has been shown to improve the survival of advanced lung cancer patients. However, most of the clinical studies were performed in the era when systemic treatment options for this disease were limited.
- Trial name
- NCT06786468
- Testing
- Early palliative care integration, Standard systemic treatment for advanced lung cancer
- Where
- Thailand
- Volunteers
- 104 people
- Sponsor
- Mahidol University
Cancer
Integrated Short-Term Palliative Rehabilitation in Incurable Cancer
The goal of this intervention trial is to determine if palliative rehabilitation in addition to usual care is more effective than usual care at improving health-related quality of life in patients with incurable solid cancer.
- Trial name
- INSPIRE (NCT05984797)
- Testing
- Integrated Short-term Palliative Rehabilitation
- Where
- 11 sites in Denmark, France and 3 more
- Volunteers
- 340 people
- Sponsor
- King's College London
Advanced Cancer
Early, Integrated, Specialized Palliative Rehabilitation
The purpose of this study is to identify whether patients with newly diagnosed advanced cancer benefit from a 12-week palliative rehabilitation program integrated with standard oncology treatment.
- Trial name
- NCT02332317
- Testing
- Palliative rehabilitation
- Where
- Denmark
- Volunteers
- 301 people
- Sponsor
- Vejle Hospital
Colorectal Cancer
Tumour Registry Colorectal Cancer
To describe treatment reality of patients with colorectal cancer treated by office-based and clinic-based medical oncologists in Germany.
- Trial name
- TKK (NCT00910819)
- Where
- Germany
- Volunteers
- 7,000 people
- Sponsor
- iOMEDICO AG
Multiple Myeloma
Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma
Multiple myeloma is a plasma cell neoplasm that can cause painful bone lesions. The main treatment for these lesions and pain control is radiotherapy, usually in daily fractions.
- Trial name
- NCT05996367
- Testing
- Single-dose involved-site radiotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Muscle-Invasive Bladder Carcinoma, Bladder Cancer Stage II
Addressing Barriers to Palliative Care Use in Bladder Cancer
Investigators plan to establish an in-depth understanding of knowledge and beliefs about palliative care in advanced Bladder Cancer patients and their caregivers, and to identify factors associated with positive and negative…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Bladder Cancer Stage II, Bladder Cancer Stage III, Bladder Cancer Stage IV
- Trial name
- NCT04598724
- Testing
- Surveys
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Pain, Nausea
Cannabis For Cancer-Related Symptoms
Clinical evidence is urgently needed to be able to advise patients on which cannabis-based products to take, or to avoid, in managing cancer-related symptoms.
- Conditions
- Pain, Nausea, Anxiety, Sleep Disturbance
- Trial name
- CAFCARS (NCT03948074)
- Testing
- Cannabis
- Where
- 8 sites in Canada
- Volunteers
- 91 people
- Sponsor
- Pippa Hawley
Metastatic Breast Cancer
Phase II PEMBROLIZUMAB + PALLIATIVE RADIOTHERAPY IN BC
This research study is studying radiation therapy in combination with an immunotherapy as a possible treatment for metastatic hormone receptor (HR) positive, HER2-negative breast cancer.
- Trial name
- NCT03051672
- Testing
- Pembrolizumab, Palliative radiotherapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dana-Farber Cancer Institute
Hepatocellular Carcinoma, Liver Metastases
Study of Palliative Radiotherapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases
The purpose of this study is to see whether one dose of palliative radiation therapy directed to the liver in combination with standard BSC might help to reduce liver pain/discomfort due to cancer when compared to getting…
- Trial name
- NCT02511522
- Testing
- Best Supportive Care, Palliative Radiation Therapy
- Where
- 7 sites in Canada
- Volunteers
- 66 people
- Sponsor
- Canadian Cancer Trials Group
Advanced Cancer, Mortality
90-Day Mortality After Emergency Department Discharge in Advanced Cancer
This retrospective observational study investigates factors associated with 90-day mortality among patients with advanced cancer who present to the emergency department (ED).
- Conditions
- Advanced Cancer, Mortality, Oncology, Emergency Department Admission
- Trial name
- CARE-90 (NCT07167095)
- Testing
- Retrospective Data Collection and Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 1,250 people
- Sponsor
- Ankara Etlik City Hospital
Cancer, Bone Metastases
MR-HIFU for Bone Metastases
The aim of this study is to evaluate effectiveness of the Philips Sonalleve MR-HIFU device for the palliation of pain in patients with bone metastases.
- Trial name
- NCT01964677
- Testing
- Magnetic Resonance Image-guided High Intensity Focused Ultrasound (MR-HIFU)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Institute of Cancer Research, United Kingdom
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