Clinical trials: Palliative Cancer
Pancreatic Neoplasm, Gastric Neoplasm
The Role of Early Systematic Best Palliative Care Versus on Request Palliative Care Consultation During Standard Oncologic Treatment for Patients With Advanced Gastric or Pancreatic Cancers: a Randomized, Controlled, Multicenter Trial.
Title: The role of early systematic best palliative care versus on request palliative care consultation during standard oncologic treatment for patients with advanced gastric or pancreatic cancers: a randomized, controlled…
- Trial name
- NCT01996540
- Testing
- Interventional arm: Early best palliative care
- Where
- 30 sites in Italy
- Volunteers
- 394 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Esophageal Cancer
Chemoradiotherapy for Advanced Esophageal Cancer
This study aims to show that the addition of carboplatin and paclitaxel chemotherapy to a palliative course of external beam radiation treatment improves both dysphagia relief and patient quality of life in patients with…
- Trial name
- PaRCUS (NCT02297217)
- Testing
- Carboplatin and Taxol (paclitaxel), External Beam Radiation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- AHS Cancer Control Alberta
Solid Cancer in a Palliative Situation With Ascites
Serum-Ascites Albumin Gradient Analysis in Cancer Patients in Palliative Care
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites.
- Trial name
- AGASA-SP (NCT03463655)
- Testing
- cirrhotic albumin, serum albumin
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Cancer, Palliative Care
Assessment of Patient Satisfaction in Palliative Cancer When They Return Home After Hospitalization in Palliative Care
The proposed work is part of a multidisciplinary approach to continuity of care in the particular context of the palliative phase of cancer.
- Conditions
- Cancer, Palliative Care, Home
- Trial name
- NCT02207543
- Testing
- Medical telephone contact
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Francois Baclesse
Prostate Cancer
Prostate Cancer Symptom Management for Low Literacy Men
This study will compare a newly-developed patient education program to help men with localized prostate cancer manage treatment-related side-effects versus usual care.
- Trial name
- NCT00983710
- Testing
- PC-PEP - Prostate Cancer Patient Education Program, Usual care
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Baylor College of Medicine
HIV Infections, Cancer
A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain
To determine the safety and efficacy of SNX-111 in controlling severe, chronic pain in cancer and AIDS patients.
- Conditions
- HIV Infections, Cancer, Pain
- Trial name
- NCT00002160
- Testing
- Ziconotide
- Where
- 44 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurex
Acute Leukemia
Emotion And Symptom-focused Engagement (EASE): An Intervention for Individuals With Acute Leukemia
The purpose of this study is to test the feasibility of an individual psychological and physical symptom intervention, called Emotion And Symptom-focused Engagement (EASE), to reduce traumatic stress and physical symptom burden…
- Trial name
- EASE (NCT02353559)
- Testing
- EASE
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University Health Network, Toronto
Health Literacy, Prostate Cancer
Cancer Literacy Education and Awareness Resources for Prostate Care
The CLEAR-PC project addresses the critical issue of low health literacy in prostate cancer prevention and care, recognising that inadequate health literacy leads to difficulties in understanding complex medical information…
- Trial name
- CLEAR-PC (NCT07437482)
- Testing
- Co-created digital health literacy intervention for prostate cancer prevention and care
- Where
- Spain
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Pediatric Cancer
Nurse-led Transitional Care to Improve Symptom Management in Childhood Cancer Survivors
This study aims to evaluate the feasibility and preliminary effectiveness of a nurse-facilitated interdisciplinary transitional care programme, based on the Omaha system, for Chinese childhood cancer survivors (CCSs) and their…
- Trial name
- NCT07273682
- Testing
- Counseling based on Omaha system, Usual Care
- Volunteers
- 68 people
- Sponsor
- The Hong Kong Polytechnic University
Non-small-cell Lung Cancer
A Phase I Study of ZD1839 and Palliative Thoracic Radiotherapy in Patients With Non-small-cell Lung Cancer
The purpose of this study is to characterize the safety profile of ZD1839 in combination with Palliative thoracic Radiotherapy in patients with non-small cell lung cancer
- Trial name
- NCT00255489
- Testing
- Gefitinib, palliative thoracic radiotherapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 36 people
- Sponsor
- AstraZeneca
Platelet Transfusion, Palliative Care
Retrospective Descriptive Study of Platelet Transfusion in Patients With Palliative Hematologic Malignancies at the University Hospital of Besançon
Development of palliative care is less effective for patients with hematologic malignancies. Limited data is available for end of life care in this population, moreover with thrombocytopenic patients.
- Trial name
- NCT03814486
- Testing
- descriptive
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Palliative Care, Acute Myeloid Leukaemia
Effectiveness of Early Intervention in Palliative Care for Acute Myeloid Leukemia Patients Comparing to Standard of Care
Hemato-oncology patients undergoing intensive chemotherapy treatments experience different types of symptoms during and after treatments, which are often refractory to the established therapy.
- Trial name
- NCT06848270
- Testing
- Early palliative care integration
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Ulcerated Cutaneous Metastases
Palliative Treatment of Ulcerated Cutaneous Metastases: Trial Between Electrochemotherapy and Radiotherapy
By applying short electric pulses to cells, the cell membranes can become permeabilised (electroporation). This can be used augment the effect of chemotherapy, by providing direct access to the cell cytosol.
- Trial name
- NCT00918593
- Testing
- Electrochemotherapy, Radiotherapy, Bleomycin
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital at Herlev
Bone Metastases, Bone Neoplasm
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP.
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
- Trial name
- FURTHER (NCT04307914)
- Testing
- External beam radiotherapy, MR-HIFU
- Where
- 6 sites in Finland, Germany and 2 more
- Volunteers
- 216 people
- Sponsor
- UMC Utrecht
Pediatric Neoplasm, Quality of Life
The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology
Over 50% of children dying from cancer still suffer from symptoms that could be effectively alleviated. The purpose of the Pediatric Quality of Life and Evaluation of Symptoms Technology (PediQUEST) Study was to evaluate whether…
- Conditions
- Pediatric Neoplasm, Quality of Life, Outcome Assessment, Palliative Care
- Trial name
- NCT01838564
- Testing
- Routine Data collection, Feedback of patient-reported outcomes
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Dana-Farber Cancer Institute
Solid Tumors, CTCL
A Study of MEDI9197 in Subjects With Solid Tumors or CTCL and in Combination With Durvalumab and/or Palliative Radiation in Subjects With Solid Tumors
To evaluate MEDI9197 when administered by intratumoral injection to subjects with solid tumors and in combination with durvalumab in subjects with solid tumors.
- Conditions
- Solid Tumors, CTCL, Cancer
- Trial name
- NCT02556463
- Testing
- MEDI9197, durvalumab
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 53 people
- Sponsor
- MedImmune LLC
Oxygen Dependent COPD, Advanced Malignancy
Changing the Paradigm of In-Hospital Cardiopulmonary Resuscitation
Outcomes after in-hospital cardiopulmonary resuscitation (CPR) are very poor, particularly in patients with oxygen dependent chronic obstructive pulmonary disease (COPD) or metastatic cancer.
- Trial name
- NCT01558817
- Testing
- Informed Assent, Informational Brochure
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Vermont
Malignant Pleural Effusion
Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion
This is prospective randomized control trial study. The aim of this study is to evaluate the efficacy of Iodopovidone solution for pleurodesis in palliative malignant pleural effusion (MPE) patients comparing to Talc.
- Trial name
- NCT02674243
- Testing
- Iodopovidone solution, Talc
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chiang Mai University
Bile Duct Obstruction, Extrahepatic, Cancer of the Pancreas
Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary Obstruction
A randomised clinical trial to compare the clinical efficacy of multiple plastic stents to fully covered self expanding metal stents in the palliation of distal malignant biliary obstruction in patients with irresectable tumours.
- Conditions
- Bile Duct Obstruction, Extrahepatic, Cancer of the Pancreas, Cancer of the Bile Duct, Biliary Stricture
- Trial name
- NCT03821025
- Testing
- Biliary stent
- Where
- South Africa
- Volunteers
- 150 people
- Sponsor
- University of Cape Town
Cancer
Low Intensity Aerobic Exercise and Active Exercises in Cancer Patients Receiving Palliative Care
To compare the effect of low intensity aerobic exercise and active ROM exercises on cancer related fatigue and its associated symptoms and quality of life in cancer patients receiving palliative care.
- Trial name
- NCT05059990
- Testing
- Low Intensity Aerobic Exercises Group, Active Exercises Group
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
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