Clinical trials: Palliative Cancer
Breast Cancer Female
REJOIN Trial for Older Breast Cancer Survivors
The purpose of this pilot intervention study is to assess feasibility and the potential intervention effects of a self-management intervention (combining education- and exercise-based strategies) for improving arthralgia (joint…
- Trial name
- REJOIN (NCT03955627)
- Testing
- Relieving Joint Pain and Improving AI Adherence in Older Breast Cancer Survivors (REJOIN)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
Advanced Breast Cancer, Advanced Prostate Cancer
Engage Psychosocial Intervention for Cancer Symptoms
The goal of this clinical trial is to test the efficacy a new psychosocial symptom management intervention called ENGAGE for patients with Stage IV breast, prostate, lung, or colorectal cancer.
- Conditions
- Advanced Breast Cancer, Advanced Prostate Cancer, Advanced Lung Cancer, Advanced Colorectal Carcinoma
- Trial name
- Engage (NCT06555588)
- Testing
- ENGAGE, Supportive Care
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Duke University
Cervical Carcinoma, Ovarian Carcinoma
Palliative Care in Improving Quality of Life in Patients With High Risk Primary or Recurrent Gynecologic Malignancies
This randomized clinical trial studies a palliative care program in improving the quality of life of patients with high-risk gynecologic malignancies that is original or first tumor in the body (primary) or has come back…
- Conditions
- Cervical Carcinoma, Ovarian Carcinoma, Primary Peritoneal Carcinoma, Recurrent Cervical Carcinoma
- Trial name
- NCT02578888
- Testing
- Palliative Therapy, Palliative Therapy + idiographic
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Albert Einstein College of Medicine
Secondary Bone Cancer, Bone Metastases
MRgFUS Versus EBRT in Patients With Metastatic Non-spinal Bone Disease
The objective of this trial is to collect and compare safety and effectiveness data of Magnetic Resonance guided Focused Ultrasound (MRgFUS) using the ExAblate 2100 device and radiotherapy in the treatment of metastatic bone…
- Trial name
- NCT03404362
- Testing
- Bone Metastases Pain treatment
- Where
- 2 sites in Italy
- Volunteers
- 198 people
- Sponsor
- University of Roma La Sapienza
Chronic Hepatitis B, Hepatocellular Carcinoma
Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most common solid cancers worldwide, and chronic hepatitis B virus (HBV) infection is the most common etiology of HCC in Asia.
- Trial name
- NCT01872988
- Testing
- Tenofovir
- Where
- 4 sites in Taiwan
- Volunteers
- 320 people
- Sponsor
- Taichung Veterans General Hospital
Depression
CALM Phase 2b Pilot
Managing Cancer And Living Meaningfully (CALM) is a brief psychotherapy designed to alleviate distress in advanced cancer. In an earlier intervention-only pilot trial, CALM was associated with reductions in depressive symptoms…
- Trial name
- CALM (NCT02353546)
- Testing
- CALM
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Biliary Tract Neoplasms, Neoplasms
Evolution® Biliary Stent System Clinical Study
The Evolution® Biliary Stent System Clinical Study is a clinical trial on a commercially available device to gather physician experience with the Cook Evolution® Biliary Stent System for the palliation of cancer in the biliary…
- Conditions
- Biliary Tract Neoplasms, Neoplasms, Gastrointestinal Diseases, Digestive System Diseases
- Trial name
- NCT01962168
- Testing
- Evolution® Biliary Stent - Uncovered
- Where
- 9 sites in United States, Canada
- Volunteers
- 113 people
- Sponsor
- Cook Group Incorporated
Small Intestinal Neuroendocrine Tumor
Resection of the Primary Tumor vs no Resection in Asymptomatic Patients With Unresectable Synchronous Liver Metastases From siNEN
Small Intestinal neuroendocrine Tumors (SiNETs) incidence is rising. Most of siNETs primaries are localized in jejunum/ileum. At the diagnosis, 50-70% of them present either lymph node (LN) and/or liver metastases (LM).
- Trial name
- SI-NET (NCT03442959)
- Testing
- Data record
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Child With Cancer, Muscular Atrophy
Nurse Parental Support Using a Mobile App in Symptom Management for CMC
Parents of children with medical complexity (CMC) are suffering from high level of stress. These CMC get multisystem diseases, including severe neurologic conditions or cancer, resulting in potential premature death.
- Conditions
- Child With Cancer, Muscular Atrophy, Child With Cerebral Palsy, Child With Medical Complexity
- Trial name
- NCT05765643
- Testing
- Nurse parental support in symptom management using a mobile health App
- Where
- 2 sites in Hong Kong
- Volunteers
- 96 people
- Sponsor
- The Hong Kong Polytechnic University
Neoplasms
Oral Symptom Assessment Scale (OSAS): Validity and Reliability
Oral (mouth) symptoms are very common and often bothersome in patients with cancer. The best way to assess these symptoms is using a patient-rated symptom assessment scale.
- Trial name
- NCT04932317
- Where
- Ireland
- Volunteers
- 54 people
- Sponsor
- Our Lady's Hospice and Care Services
Cancer, Cancer Cachexia
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular…
- Conditions
- Cancer, Cancer Cachexia, Inflammation
- Trial name
- PROTECT (NCT04065815)
- Testing
- Resistance Training, WB-EMS, High-intensity interval training (HIIT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colorectal Cancer Metastatic
Effectiveness Study of Resection of Primary Tumor in Stage IV Colorectal Cancer Patients
There is still no perfect treatment suggestion for patients with asymptomatic colorectal cancer with unresectable metastatic disease.
- Trial name
- NCT02149784
- Testing
- Surgical resection of primary tumor
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sun Yat-sen University
Advanced NSCLC, First Line Treatment
POSITIVE - Study (Part III) Heidelberg
The investigators plan to evaluate, in a randomized, controlled phase III trial in patients with advanced non-small cell lung cancer (NSCLC), the effects of a 24-week exercise intervention program (EIP) on quality of life…
- Trial name
- POSITIVE (NCT02055508)
- Testing
- Exercise Intervention, Care-Management-Phone-Calls
- Where
- Germany
- Volunteers
- 232 people
- Sponsor
- German Cancer Research Center
Cancer
Physical Activity and Functioning in Palliative Cancer Patients - a Clinical Randomised Trial
The project consists of two studies where we want to throw light on the importance of physical activity/exercise to maintain physical function among cancer patients whose disease is not responsive to curative treatment.
- Trial name
- NCT00397774
- Testing
- Physical exercise, best supportive care
- Where
- 5 sites in Norway
- Volunteers
- 231 people
- Sponsor
- Norwegian University of Science and Technology
Cancer, Congestive Heart Failure (CHF)
Outlook Quality of Life Intervention Study
The purpose of this study is to determine whether discussions of life story, forgiveness, and future goals improve quality of life for patients with serious illness.
- Conditions
- Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD), End Stage Renal Disease (ESRD)
- Trial name
- NCT01044290
- Testing
- Life Completion, Attention Control
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- VA Office of Research and Development
Tumor in Upper Gastrointestinal Canal or Patients With Colorectal Cancer
Observational Study of Early Contact With Palliative Care Unit for Patients Receiving First Line Palliative Chemotherapy With Cancer in Upper Gastrointestinal Canal, or Second Line Palliative Chemotherapy in Patients With Colorectal Cancer - an Open, Randomised Investigator Initiated Trial.
In this trial, patients with cancer in the upper gastrointestinal canal who are going to receive first line palliative chemotherapy and patients with colorectal cancer who are going to receive second line palliative chemotherapy…
- Trial name
- ALLAN (NCT02246725)
- Testing
- Contact with palliative care unit.
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Lund University Hospital
Cancer
Evaluation of the Efficacy of Diuretics for Symptomatic Malignant Ascites Episodes in Advanced Stage of Cancer (DIASC)
While some authors recommend diuretics as the first treatment to initiate for symptoms caused by malignant ascites (MA), their prescription is variable. No randomized, controlled study has assessed their benefit in this context.
- Trial name
- NCT02501213
- Testing
- Spironolactone (+/- Furosemide)
- Where
- 15 sites in France
- Volunteers
- 14 people
- Sponsor
- Centre Oscar Lambret
Chemotherapy-induced Neutropenia, Chemotherapy-induced Nausea and Vomiting
Community-Led Action Research in Oncology: Improving Symptom Management
This study will be conducted at La Liga Contra el Cancer in San Pedro Sula, Honduras. The overall objective of this project is to improve symptom management for patients undergoing chemotherapy in Honduras.
- Conditions
- Chemotherapy-induced Neutropenia, Chemotherapy-induced Nausea and Vomiting, Anxiety, Depression
- Trial name
- CLARO (NCT03208816)
- Testing
- symptom management program for chemotherapy patients
- Where
- 2 sites in United States, Honduras
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pelvic Cancer, Radiotherapy
Short Course Radiation Therapy in Palliative Treatment of Pelvic Cancer
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic pelvic malignant lesions
- Conditions
- Pelvic Cancer, Radiotherapy, Palliative Care
- Trial name
- NCT03804333
- Testing
- standard treatment, short course treatment
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Oesophageal Cancer
Role of Radiotherapy Following Oesophageal Stenting in Cancer
To assess the benefits of oesophageal stenting and external beam radiotherapy over oesophageal stenting alone in patients with inoperable oesophageal cancer
- Trial name
- NCT01179074
- Testing
- oesophageal stenting with self expandable metal stent, Oesophageal stent followed by external beam radiotherapy
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences
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