Clinical trials: Palliative Cancer
HER2 Negative Gastric Cancer
Comparison of Efficacy and Frequency of Adverse Events of 1st Line Palliative Chemotherapy EOX and mDCF Regimens in Advanced HER2-negative Gastric Carcinoma
The purpose of the study is to compare efficacy and safety of palliative chemotherapy EOX and mDCF regimens in the first-line treatment of patients with advanced HER2-negative gastric and gastroesophageal junction (GEJ)…
- Trial name
- NCT02445209
- Testing
- EOX, mDCF
- Volunteers
- 56 people
- Sponsor
- Jagiellonian University
Neoplasms, Nursing Caries
Nurse-Led Electronic Patient-Reported Outcome System to Improve Quality of Life in Chemotherapy Patients
Chemotherapy often causes burdensome symptoms that affect daily life and reduce patients' quality of life. This study aims to test whether an information-based symptom management program can help cancer patients better manage…
- Trial name
- NURSE-PRO (NCT07144449)
- Testing
- Nurse-Led ePRO System, Usual Care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- CHIAO-CHI KUAN
Metastatic or Recurrent Lesions in the Spine, Metastatic or Recurrent Lesions in the Pelvis
Image-Guided Navigation for High Dose Rate Temporary Interstitial Brachytherapy in the Palliative Management of Previously Treated Tumors of the Spine and Pelvis
The purpose of this study is to see if using a form of imaging during surgery helps the doctors to guide the placement of radiation catheters more accurately.
- Trial name
- NCT01757717
- Testing
- Ir-192 high dose rate (HDR)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
Examining Early Palliative Care in Newly Diagnosed Cancer Patients
To understand the impact of initiation of palliative care in this low-resource setting, and whether palliative care is a cost-reducing intervention that will improve patient-reported outcomes and quality of life.
- Trial name
- NCT03712436
- Testing
- Palliative care, Standard oncological care
- Where
- Ethiopia
- Volunteers
- 98 people
- Sponsor
- Yale University
Cancer of Pancreas, Cancer of Stomach
Early Support in Primary Care for People Starting Treatment for Cancer
This is a feasibility, randomised controlled trial (RCT) of a person-centred care planning intervention involving patients recently diagnosed with a poor prognosis cancer who are starting a palliative oncology treatment in a…
- Conditions
- Cancer of Pancreas, Cancer of Stomach, Cancer of Esophagus
- Trial name
- GI-ACP (NCT03719716)
- Testing
- Anticipatory care planning letter
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- NHS Lothian
Carcinoma, Non-Small-Cell Lung
Prospective Trial of Induction Immunotherapy in Locally Advanced or Oligometastatic NSCLC Without a Primary Curative Option
In a certified lung- cancer center, patients with NSCLC and a potentially curative stage (including patients with oligometastatic disease) are prospectively enrolled if curative treatment (either definitive radio-chemotherapy or…
- Trial name
- KOMPASSneo (NCT04926584)
- Testing
- induction therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Klinikum Esslingen
Non-small Cell Lung Cancer
Phase II Trial of Erlotinib and Concurrent Palliative Thoracic Radiation Therapy for Non-small Cell Lung Cancer (PEARL)
To improve the clinical outcomes of patients with non-small cell lung cancer treated with radiation therapy.
- Trial name
- NCT00391248
- Testing
- Erlotinib
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Cancer, Anorexia
Orexigenic Therapy With Delta-9-tetrahydrocannabinol in Advanced Cancer Patients With Chemosensory Abnormalities - a Pilot Study
To investigate delta-9-tetrahydrocannabinol's (THC) ability to increase food intake and improve food enjoyment for advanced cancer patients with taste and/or smell (chemosensory) abnormalities.
- Conditions
- Cancer, Anorexia, Taste Disorders, Olfactory Disorders
- Trial name
- NCT00316563
- Testing
- Marinol (Dronabinol)
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Alberta Health services
Advanced Cancer
Integration of Palliative Care in an Oncology and Hematology Unit
The main goal of this study is to assess retrospectively the integration of Palliative Care in an oncology and hematology unit. The investigators will study the last six month of life on advanced cancer patients and retrieve data…
- Trial name
- NCT04089306
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer, Cancer Cachexia
Cachexia and Gut Microbiota in Patients With Breast Cancer Receiving Home Care
This study aims to evaluate the possible association between cancer cachexia and Gut Microbiota (GM) in patients with Breast Cancer (BC) cared at home.
- Trial name
- GM_ANT (NCT07653698)
- Testing
- Probiotic Mixture
- Volunteers
- 140 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Nutrition Aspect of Cancer, End Stage Cancer
Efficacy of Parenteral Nutrition in Patients at the Palliative Phase of Cancer.
In malnourished patients in the palliative phase of cancer, the question is raised of the relevance of implementing artificial nutritional assistance instead of oral feeding when this is possible.
- Trial name
- ALIM-K (NCT02151214)
- Testing
- Parenteral nutrition
- Where
- 13 sites in France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Colorectal Cancer, Psycho-Oncology
The Effects of Nurse Navigation Program on Symptom Management and Psychosocial Adjustment in Colorectal Cancer Patients
This study was conducted to examine the effect of the nurse navigation program (NNP) applied to patients with colorectal cancer on symptom management and psychosocial adjustment to the disease.
- Conditions
- Colorectal Cancer, Psycho-Oncology, Nursing
- Trial name
- NCT05571098
- Testing
- individualized colorectal cancer education, psycho-oncological counseling, telephone support hotline service
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Advanced Cancer
Early Palliative Care on Quality of Life of Patients With Advanced Pancreas Cancer
The primary objective is to explore the impact of early palliative care on quality of life in patients with advanced pancreatic cancer.
- Trial name
- NCT03837132
- Testing
- Palliative care assessment
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Breast Cancer, Breast Cancer Survivorship
Patient-Initiated Follow-Up for Women After Early Breast Cancer Treatment (LYSA2PIFU)
Women treated for early-stage breast cancer commonly experience ongoing treatment-related symptoms while receiving adjuvant endocrine therapy.
- Conditions
- Breast Cancer, Breast Cancer Survivorship, Cancer Survivorship, Endocrine Therapy
- Trial name
- LYSA2PIFU (NCT07840534)
- Testing
- Patient-Initiated Follow-Up and ePRO Symptom Management
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University College Cork
Cancer
Implementation of a Return Home With a Hospitalization at Home or With a Home Health Care Provider From the Services of Oncopneumology, Oncology and Hematology of University Hospital of Strasbourg
Hospitalization at home is booming. It is designed to meet the demands of patients and their families to continue care at home. It partially solves the problem of the lack of places in the "long-term care" structures and allows…
- Trial name
- NCT03217864
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Pancreas Cancer
Integrating Palliative Care and Modern Palliative Care Tools Into the Care of Patients With Pancreas Cancer
The main purpose of this study is to evaluate the acceptance by patients with metastatic pancreas cancer of integrating palliative care with usual cancer treatment.
- Trial name
- iPC3 (NCT01784081)
- Testing
- Palliative care with decision aids
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Ovarian Cancer, Ovarian Neoplasms
EDMONd - Elemental Diet in Bowel Obstruction
A feasibility study to provide 'proof of concept' of Elemental Diet (ED) as an acceptable/ useful feeding option for patient with inoperable malignant bowel obstruction and to examine the impact of ED on quality of life
- Conditions
- Ovarian Cancer, Ovarian Neoplasms, Ovarian Disease, Peritoneal Neoplasms
- Trial name
- EDMONd (NCT03150992)
- Testing
- Elemental 028 Extra Liquid
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Professional Quality of Life, Palliative Care
Effectiveness of the Mindful Compassion Care Program for Healthcare Professionals in Oncology and Palliative Care
This randomized controlled trial aims to evaluate the effectiveness of the Mindful Compassion Care Program (MCCP), a mindfulness- and compassion-based intervention designed to enhance the emotional and professional well-being of…
- Conditions
- Professional Quality of Life, Palliative Care, Oncology
- Trial name
- MCCP (NCT07248111)
- Testing
- MCCP
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Palliative Care, Pain
A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy.
The purpose of this study is to determine the effective dose range and to demonstrate a non-effective dose range of Sativex in patients with advanced cancer, who experience inadequate pain relief even though they are on optimized…
- Conditions
- Palliative Care, Pain, Cancer
- Trial name
- SPRAY (NCT00530764)
- Testing
- Sativex Low Dose, Sativex Medium Dose, Sativex High Dose
- Where
- 110 sites in United States, Belgium and 14 more
- Volunteers
- 360 people
- Sponsor
- GW Pharmaceuticals Ltd
Advanced Cancer
Primary Palliative Care for Patients With Advanced Hematologic Malignancies
This study seeks to develop and pilot-test an oncology nurse-led care management intervention to meet the primary palliative care needs of patients with advanced hematologic malignancies.
- Trial name
- NCT02992171
- Testing
- care management by oncology nurses
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
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