Clinical trials: Palliative Cancer
Colorectal Cancer, Steatohepatitis
A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis
This multicenter randomized, placebo-controlled phase II study will enroll 132 first-line palliative treated subjects with metastatic KRAS wild type CRC.
- Trial name
- G-LUCAS (NCT01523639)
- Where
- 7 sites in Austria
- Volunteers
- 8 people
- Sponsor
- Austrian Breast & Colorectal Cancer Study Group
Advanced Gastric or EGJ Cancer
Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy
This clinical trial will evaluate whether it is beneficial in terms of prolongation of survival to combine FOLFIRI (standard treatment) with ramucirumab compared to the standard treatment of ramucirumab plus paclitaxel in…
- Trial name
- RAMIRIS (NCT03081143)
- Testing
- FOLFIRI, Ramucirumab, Paclitaxel
- Where
- 16 sites in Austria, Germany and 1 more
- Volunteers
- 429 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Brain Metastases, Adult, Cancer Brain
Hypofractionated Brain Radiationcavity
Stereotactic radiosurgery or hypofractionated radiotherapy of the resection cavity after metastasectomy in cancer patients with brain metastases
- Trial name
- NCT03561896
- Testing
- IGRT, SRS
- Where
- 6 sites in Switzerland
- Volunteers
- 56 people
- Sponsor
- Oncology Institute of Southern Switzerland
Supportive Care, Cancer
Feasibility Study of the Advanced Symptom Management System (ASyMS) in Canadian Cancer Patients
The Advanced Symptom Monitoring and Management System - Canada (ASyMS-Can) is a remote phone-based symptom management system that prompts patient self-care and clinician telephone triage and intervention based on alerts for…
- Trial name
- ASyMS-Can (NCT03335189)
- Testing
- ASyMS-Can
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Metastatic Cancer
Assessment of the Prevalence of Sarcopenia in Early Palliative Cancer Patients
Cancer is one of the leading causes of death in the world after cardiovascular disease (8.7 million deaths in 2015 for 17.5 million cases) 1.
- Trial name
- SPACE (NCT04714203)
- Testing
- sarcopenia assessment
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Weprom
Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer
Good Choice of pALliative Chemotherapy to Patient With Pancreatic Cancer ; GemcitAbine Therapy vs FOLFORINOX therapY
The study objectives are to find out: 1) palliative chemotherapy patterns and prognosis in patients with locally advanced or metastatic pancreatic cancer in Korea's real clinical settings, and 2) reasons adopted by clinicians in…
- Trial name
- GALAXY (NCT04789980)
- Where
- South Korea
- Volunteers
- 799 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Communication, End of Life
Improving Breaking Bad News in Pediatrics by Simulated Communication
Breaking bad news, especially a death notice, is an essential part of the medical profes-sional communication. Being inadequately trained in those skills this may result in un-pleasant psychosocial consequences for everyone…
- Conditions
- Communication, End of Life, Pediatric ALL
- Trial name
- SimCom (NCT06376188)
- Testing
- communication training
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Prostate Cancer
Saw Palmetto: Symptom Management for Men During Radiation Therapy
The aim of this study is to test whether Saw Palmetto, is useful in preventing or reducing the side effects for men undergoing radiation therapy for prostate cancer.
- Trial name
- NCT01585246
- Testing
- Saw Palmetto, soybean oil soft gel
- Where
- 6 sites in United States
- Volunteers
- 48 people
- Sponsor
- Michigan State University
Lymphoma
Low-dose Radiotherapy for Diffuse Large B-cell Lymphoma
Patients with Diffuse Large B-cell Lymphoma with indication for palliative radiotherapy are treated with low-dose radiation (2 x 2 Gy) to the symptomatic sites only.
- Trial name
- NCT02803840
- Testing
- Low-dose radiotherapy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Caregiver, Psychological Impact of Cancer and Its Treatment
Palliative Care Intervention in Improving Symptom Control and Quality of Life in Patients With Stage II-IV Non-small Cell Lung Cancer and Their Family Caregivers
This clinical trial studies a palliative care intervention in improving symptom control and quality of life in patients with stage II-IV non-small cell lung cancer and their family caregivers.
- Conditions
- Caregiver, Psychological Impact of Cancer and Its Treatment, Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer
- Trial name
- NCT02243748
- Testing
- Palliative Therapy, quality-of-life assessment, questionnaire administration
- Where
- 5 sites in United States
- Volunteers
- 361 people
- Sponsor
- City of Hope Medical Center
Brain Tumor, Pediatric, Brainstem Glioma, Brain Tumor, Pediatric, Recurrent
Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca
This Protocol is a pilot, clinical interventional study to selected patients between five and fourteen years of both sexes, carriers of the diagnosis of glioma brain stem and high grade recurrent in the central nervous system…
- Trial name
- NCT03250520
- Testing
- Platinum acetylacetonate (1% wt) supported by sol-gel technology functionalized titania
- Where
- Mexico
- Volunteers
- 8 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Unspecified Adult Solid Tumor, Protocol Specific
Extracranial Stereotactic Radiosurgery in Treating Patients With Solid Tumors
RATIONALE: Extracranial stereotactic radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Trial name
- NCT00311597
- Testing
- Radiosurgery
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Wake Forest University Health Sciences
Advanced Cancer
Feasibility of Home vs. Hospital Based Resistance Training for Advanced Cancer Patients
Cancer causes 8.2 million deaths each year, with an estimated worldwide cost of $895 billion. Pharmacological treatments provide improvements in expected survival and symptoms, but at cost of a high rate of toxicities and…
- Trial name
- NCT02930876
- Testing
- Resistance training
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- King's College London
Palliative Care, Cancer
Attitudes Towards Deprescribing Medications in Cancer Patients and Impact of Educational Intervention by a Clinical Pharmacist
Participation in this study consists in responding to some questions from two questionnaires in Romanian about how participants feel about deprescribing, participants' treatment and how participants understand medical…
- Trial name
- NCT06771999
- Testing
- Educational intervention by a clinical pharmacist
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Unspecified Adult Solid Tumor, Protocol Specific
Palliative Care Intervention in Improving Quality of Life, Psychological Distress, and Communication in Patients With Solid Tumors Receiving Treatment
This pilot randomized clinical trial studies palliative care intervention in improving quality of life, psychological distress, and communication in patients with solid tumors receiving treatment on phase I trials.
- Trial name
- NCT01828775
- Testing
- palliative care, quality-of-life assessment, survey administration
- Where
- 2 sites in United States
- Volunteers
- 480 people
- Sponsor
- City of Hope Medical Center
Colorectal Cancer, Palliative Medicine
Efficacy of Ginseng for Patients on Regorafenib
This is a randomized, multi-center phase II study of ginseng in colorectal cancer patients treated with regorafenib to determine if ginseng will reduce fatigue in this patient population and improve adherence to regorafenib.
- Conditions
- Colorectal Cancer, Palliative Medicine, Supportive Care
- Trial name
- NCT02581059
- Testing
- Regorafenib, Ginseng
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Oligometastatic Disease
Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care
Currently, the usual standard of palliative treatment used in patients with diagnosed oligometastatic cancer in accordance with the local clinical recommendations is chemotherapy and/or a symptomatic course of radiation therapy…
- Trial name
- NCT06556550
- Testing
- stereotactic ablative radiation therapy, palliative radiation therapy, Chemotherapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Radiological Centre of the Ministry of Health of Russia
Hepatocellular Carcinoma
Systemic Chemotherapy Versus Transcatheter Arterial Chemoembolization(TACE) for Hepatocellular Carcinoma
The purpose of this study is to determine that systemic chemotherapy is superior to transcatheter arterial chemoembolization in prolonging progression-free survival（PFS） in patients with Advanced Hepatocellular Carcinoma.
- Trial name
- NCT02585479
- Testing
- Pirarubicin, Oxaliplatin, Lipiodol
- Sponsor
- Guangxi Medical University
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Early Palliative Care for Patients With Haematological Malignancies
Patients suffering from haematological disease present symptoms of discomfort and currently benefit from palliative care skills only for the management of their end-of-life.
- Conditions
- Acute Myeloid Leukemia, Myelodysplastic Syndrome, Diffuse Large B Cell Lymphoma, Palliative Care
- Trial name
- CALVI (NCT03800095)
- Testing
- Early palliative care integration
- Where
- 6 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Gynaecological Cancer, Chemotherapy
Effects of Symptom Management Education With Mobile Application in Gynecological Cancer Patients Receiving Chemotherapy
Gynaecological cancers, which have an important place among the cancers seen both in the world and in our country. Chemotherapy, which is one of the most commonly used and basic methods in cancer treatment, causes many physical…
- Conditions
- Gynaecological Cancer, Chemotherapy, Nursing Care
- Trial name
- NCT06713122
- Testing
- İntervention Group- Group receiving Symptom Management Training with Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Esra Nur Erdoğan
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