Clinical trials: Palliative Cancer
Malignant Dysphagia, Esophageal Cancer
Optimal Management of Malignant Dysphagia
According to the Canadian Cancer Society there are approximately 1700 new cases of esophageal cancer per year in Canada. As most of these patients are diagnosed in advanced stages of the disease, 1800 deaths are estimated from…
- Trial name
- NCT01366833
- Testing
- Brachytherapy, Stent insertion
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma
Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer
This phase II trial studies the effects of interstitial photodynamic therapy in patients with head and neck cancer that has come back.
- Conditions
- Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma, Recurrent Lip and Oral Cavity Squamous Cell Carcinoma, Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary
- Trial name
- NCT02068157
- Testing
- Laboratory Biomarker Analysis, Photodynamic Therapy, Porfimer Sodium
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Roswell Park Cancer Institute
Refractory Malignant Ascites
Palliative Care Outcomes in the Management of Malignant Ascites by Interventional Radiology
Malignant ascites leads to significant morbidity in patients with terminal cancer. Paracentesis can provide relief, but repeat hospital visits, pain, and short duration of relief after paracentesis are detrimental to quality of…
- Trial name
- NCT02477657
- Testing
- Paracentesis, Tunneled Intraperitoneal Drain (IPD), Peritoneal-Venous shunts (PVS)
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Neoplasms
Immunostimulating Interstitial Laser Thermotherapy in Solid Cancers
Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue…
- Trial name
- NCT02690428
- Testing
- Immunostimulating Interstitial Laser Thermotherapy
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- Clinical Laserthermia Systems AB
Cancer
Evaluating the CAREchart@Home™ Program for Enhancing After-hours Cancer Care
The objective of the current project is to pilot the evaluation of the health and economic benefits of having online access to health information in the context of providing telemedicine support for oncology patients receiving…
- Trial name
- NCT04232709
- Testing
- Shared electronic patient record
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Women's College Hospital
Peripheric Neuropathy
Effect of Hilotherapy in the Management of Symptoms Related to Taxane-Associated Peripheral Neuropathy
In this randomized controlled study, it was aimed to determine the effect of hilotherapy on quality of life and comfort level in the management of symptoms related to taxane-associated peripheral neuropathy in patients with…
- Trial name
- NCT07345221
- Testing
- Hilotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Nuran Ayşen Pamir Aksoy
Cancer
SymptomCare@Home: Deconstructing an Effective Symptom Management Intervention
This project will determine the most important and cost effective components of SymptomCare@Home, a new approach to cancer chemotherapy symptom care that has been shown to reduce problematic symptoms through automated daily…
- Trial name
- SCH (NCT02779725)
- Testing
- SCC, Nurse Practitioner, DSS
- Where
- United States
- Volunteers
- 884 people
- Sponsor
- University of Utah
Metastatic Malignant Female Reproductive System Neoplasm
Single Fraction or Multi-fraction Palliative Radiation Therapy for the Improvement of Quality of Life in Patients With Metastatic Gynecologic Cancers
This phase II trial studies if a single session of palliative radiation therapy can help improve symptoms of gynecologic cancers that have spread to other places in the body (metastatic) and that affect quality of life as well or…
- Trial name
- NCT04516135
- Testing
- 3-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, Quality-of-Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Oral Complication, Cancer
Oral Assessment of Symptoms in Advanced Cancer
Observational study of prevalence of oral symptoms in patients with advanced cancer using a novel questionnaire ("Oral symptom assessment scale")
- Trial name
- OASis (NCT04404920)
- Testing
- Questionnaire
- Where
- 11 sites in United Kingdom
- Volunteers
- 253 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Lung Cancer
PAlliative RAdioTherapy to Lung Cancer A Randomized Multicentre Phase III Study
The aim of this study is to examine if a shorter palliative radiotherapy fractionation scheme of 20 Gy / 4 F can reduce the early oesophageal toxicity compared to 30 Gy / 10 F in patients with lung cancer in performance status…
- Trial name
- PARAT (NCT03632603)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 1,184 people
- Sponsor
- University of Aarhus
Cancer
Caregivers' Strengths-Skills: Managing Older Cancer Patients' Symptoms
Caregiver education and training programs that specifically target caregiver informational and training needs during the survivorship period have been limited.
- Trial name
- FamCare (NCT03532061)
- Testing
- FamCare Program, Caregiver Support Group
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- New York University
Cancer
Integral Attention Program With or Without Palliative Chemotherapy in Advanced Cancer Patients
The purpose of this clinical trial is to compare a non-pharmaceutical intervention (Integral Attention Program or PAI) versus standard palliative chemotherapy treatment plus PAI in patients with advanced cancer who have already…
- Trial name
- PAI (NCT01949974)
- Testing
- Standard Palliative Chemotherapy, Integral Attention Program (PAI)
- Where
- 3 sites in Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Adolescent and Young Adult Cancer Patient
Adolescents and Young Adults (AYAs) With Advanced Cancer
This study aims to develop and test the feasibility and acceptability of a psychosocial symptom management intervention designed to meet the unique needs of Adolescents and Young Adults (AYAs) with advanced cancer.
- Trial name
- NCT05593016
- Testing
- Symptom Management for Improved Physical and Emotional Wellbeing (SMILE), Education Control Arm
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Duke University
Breast Cancer, Metastatic Breast Cancer
Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
This study will examine unmet exercise needs among patients with metastatic breast cancer (MBC) at UNC and assess whether participation in Get Real and Heel (GRH) can increase physical activity.
- Trial name
- NCT07313306
- Testing
- The Real and Heel (GRH)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Head and Neck Cancer
MRG FU With Radiotherapy for Palliation of H&N Cancer
Head and neck cancer is the sixth most common form of malignancy world-wide. Surgery, chemotherapy and radiation are associated with a high burden of side effects; tumour recurrence within the neck continues to be a major cause…
- Trial name
- NCT03218475
- Testing
- MR Guided Focused Ultrasound
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Pain Management
mHealth Intervention for Pain Self Management
This is a feasibility pilot test of a single-arm intervention to evaluate the beta version of an mHealth app-based behavioral intervention prior to scaling for a randomized controlled trial (RCT).
- Conditions
- Pain, Pain Management, Symptom Monitoring, Symptom Management
- Trial name
- PsyMINT (NCT07332377)
- Testing
- Mobile Health (mHealth) Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Cancer
Evaluation of Multidisciplinary Palliative Care on Terminal Cancer Patients in Taiwan
The purpose of the study is to compare the quality of dying and death of terminal cancer patients from the perspectives of medical staff and main care giver (family). The hypothesis is that their view points will be different.
- Trial name
- NCT01103700
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cancer
Care Partners: Web-based Support for Caregivers of Veterans Undergoing Chemotherapy
Given the growing strain on the Veterans Administration resulting from increasing caseloads of cancer patients, interventions are badly needed that assist patients in managing their illness, improve quality of life and avoid…
- Trial name
- NCT00983892
- Testing
- Caregiver website
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Inoperable Tumors of the Bile Duct
A Trial Comparing the Uncovered to the Covered Wallstent in the Palliation of Malignant Bile Duct Strictures
The purpose of the study is to determine the best management of bile duct narrowing (stricture) due to inoperable tumors. The bile duct is a tube that carries bile formed in the liver to the small bowel to digest fats.
- Trial name
- Wallstent (NCT01047332)
- Testing
- Partially Covered Wallstent, Uncovered Wallstent
- Volunteers
- 129 people
- Sponsor
- Brigham and Women's Hospital
Palliative Care, Cancer Liver
Early Palliative Care Integration in Interventional Cancer Care
A mixed methods randomized control trial assessing the impact of early palliative care incorporation in liver cancer and metastatic colorectal cancer on caregiver well-being, patient physical and psychosocial outcomes, and health…
- Conditions
- Palliative Care, Cancer Liver, Cancer Colon
- Trial name
- EPIICC (NCT03185416)
- Testing
- Palliative Care Training
- Sponsor
- University of Miami
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