Clinical trials: Palliative Care, Patient Care
Cancer Pain, Erector Spinae Plane Block
Intermittent Erector Spinae Plane Block Via Subcutaneous Port for Cancer Pain
Cancer-related pain is a common and challenging problem in patients with lung cancer, often requiring long-term pain management.
- Trial name
- NCT07396558
- Testing
- Erector Spinae Plane Block
- Where
- Vietnam
- Volunteers
- 180 people
- Sponsor
- Hanoi Medical University
Cancer, Chronic Liver Disease (CLD)
Identification of Patients With Advanced Chronic Diseases in Need of Palliative Care
Patients with advanced chronic diseases often have complex health needs and may benefit from palliative care. However, many of these patients are not identified early enough to receive appropriate palliative care interventions.
- Conditions
- Cancer, Chronic Liver Disease (CLD), Heart Failure Chronic, Chronic Kidney Disease (Stages 4 and 5)
- Trial name
- NECPAL_HUIL (NCT07387224)
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Infanta Leonor University Hospital
COPD, ESRD
Randomized Evaluation of Default Access to Palliative Services
This is a large pragmatic, randomized controlled trial to test the real-world effectiveness of inpatient palliative care consultative services in improving a number of patient- and family-centered processes and outcomes of care…
- Conditions
- COPD, ESRD, Dementia
- Trial name
- REDAPS (NCT02505035)
- Testing
- Default ordering of palliative consult
- Where
- 11 sites in United States
- Volunteers
- 34,239 people
- Sponsor
- University of Pennsylvania
Palliative Care
Improvement of Support to Caregivers of Patients in Specialized Palliative Care at Home
The aim of the project is to evaluate the use of the caregiver-led 'CSNAT intervention' to identify, prioritize and address support needs among caregivers of patients who are starting in specialized palliative care at home in…
- Trial name
- NCT03466580
- Testing
- The Carer Support Needs Assessment Tool (CSNAT) intervention
- Where
- 10 sites in Denmark
- Volunteers
- 466 people
- Sponsor
- Bispebjerg Hospital
Cancer
m-Palliative Care Link: Improving Palliative Care for Late Stage Tanzanian Cancer Patients
This work aims to improve late-stage cancer patients' access to high quality, patient-centered symptom assessment and control via the creation, field test, and outcomes assessment of a scalable mobile application (mPalliative…
- Trial name
- NCT03634696
- Testing
- mPCL, Usual Care
- Where
- Tanzania
- Volunteers
- 98 people
- Sponsor
- Susan Miesfeldt
Support, Family
The Effect of Psychoeducation on Hopelessness, Death Anxiety and Caregiver Burden
This study was conducted to determine the effect of Watson Human Caring Model-based psychoeducation given to the relatives of patients receiving palliative care on hopelessness, death anxiety and the burden of care.
- Trial name
- NCT06154759
- Testing
- Watson Human Caring Model-based psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara Medipol University
Advanced Cancer
Palliative Care Referral System (PCRS) for Cancer Patients With Advanced Disease
Early palliative care (EPC) in the clinical pathway of advanced cancer patients improves symptom control, quality of life and has a positive impact on overall quality of care.
- Trial name
- PCRSS (NCT04936568)
- Testing
- Palliative Care Referral System - PCRS
- Where
- Italy
- Volunteers
- 380 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Neoplasms
A Psychosocial Intervention Plus Early Palliative Care in the Reduction of Depression of Advanced Cancer Patients
The purpose of this study is to determine whether a brief psychosocial intervention together with early palliative care are feasible, acceptable and effective in the reduction of depressive symptoms of patients with advanced…
- Trial name
- PREPArE (NCT02133274)
- Testing
- Brief Psychosocial Intervention, Early Palliative Care
- Where
- Brazil
- Volunteers
- 63 people
- Sponsor
- Barretos Cancer Hospital
Solid Cancer in a Palliative Situation With Ascites
Serum-Ascites Albumin Gradient Analysis in Cancer Patients in Palliative Care
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites.
- Trial name
- AGASA-SP (NCT03463655)
- Testing
- cirrhotic albumin, serum albumin
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Heart Failure, Heart-assist Devices
PCORI-1310-06998 Trial of a Decision Support Intervention for Patients and Caregivers Offered Destination Therapy Heart Assist Device
The left ventricular assist device (LVAD) is growing rapidly among people dying from end-stage heart failure who are unable to get a heart transplant.
- Trial name
- DECIDE-LVAD (NCT02344576)
- Testing
- DT LVAD Decision Support Intervention
- Where
- 6 sites in United States
- Volunteers
- 445 people
- Sponsor
- University of Colorado, Denver
Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD)
Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea
Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD)…
- Conditions
- Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD), Chronic Heart Failure (CHF), COPD
- Trial name
- HYPNEA (NCT07173348)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Geneva
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Optimization of STAR
The aim of this study is optimize the STAR (SympTom mAnagement self-caRe) intervention to support patients with HF in staying healthy, and particularly in self-monitoring and managing symptoms.
- Trial name
- STAR (NCT07065578)
- Testing
- STAR condition 1, STAR condition 2, STAR condition 3
- Volunteers
- 320 people
- Sponsor
- UMC Utrecht
Palliative Care
Advance Care Planning in Palliative Care
The question of the end of life is a major public health issue. In the field of palliative care, the notion of anticipation is central for people with a serious and progressive illness.
- Trial name
- ANTICIPALL (NCT05662917)
- Testing
- Individual semi-structured interviews
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Cancer
Surgery for Cancer With Option of Palliative Care Expert
Frequently people diagnosed with cancer experience physical and emotional symptoms during the course of their disease. These symptoms can be very distressing to both the patient and the family members.
- Trial name
- SCOPE (NCT03436290)
- Testing
- Palliative Care Intervention
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Cancer
Study to Compare the Safety and Tolerability of Sativex® in Patients With Cancer Related Pain
The purpose of this study is to assess the safety and tolerability of long term therapy with Sativex® and GW-2000-02.
- Trial name
- NCT00675948
- Testing
- Sativex, GW-2000-02
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Jazz Pharmaceuticals
Delirium, Locally Advanced Malignant Neoplasm
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care
This phase II/IIII trial studies how well haloperidol and lorazepam work in controlling symptoms of persistent agitated delirium in patients with cancer that has spread to other places in the body undergoing palliative care.
- Conditions
- Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm
- Trial name
- NCT03743649
- Testing
- Haloperidol, Lorazepam, Quality-of-Life Assessment
- Where
- 3 sites in United States, Brazil
- Volunteers
- 110 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Cancer, Palliative Care
Impact of a Booklet-Question List on Cancer Patients or Their Families Seeking Prognostic Information During a Palliative Care Consultation
Prospective, randomized, multicentre phase III study to evaluate the level and type of information requested by patients or families during a palliative care consultation after they have been given the Booklet-Question List (BQL).
- Trial name
- QUEPAL (NCT02854293)
- Testing
- Booklet-Question List
- Where
- 5 sites in France
- Volunteers
- 121 people
- Sponsor
- Institut Curie
Illness Terminal
Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy
The Conscious Dying/Conscious Living study will investigate the effect of KAP (ketamine-assisted psychotherapy) on individuals with terminal illness at five separate geographic locations.
- Trial name
- KRF-EOL (NCT05214417)
- Testing
- Ketamine Injectable Solution, Naturalistic Control
- Volunteers
- 120 people
- Sponsor
- The Ketamine Research Foundation
Advance Care Planning, Palliative Care
Testing a Video Decision Support Tool to Supplement Goals-of-Care Discussions
Subject preferences for care at the end-of-life show wide variability. In the setting of advanced disease, some subjects prefer all life-sustaining care while others forgo such procedures.
- Trial name
- NCT01391429
- Testing
- Video Decision Support Tool
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Boston Medical Center
Nausea, Vomiting
Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients? Formal Study
Pilot study completed - power calculation performed. Now formal double blind randomized study comparing active with placebo wristbands for nausea in palliative care patients to be carried out.
- Trial name
- NCT00550251
- Testing
- Acupressure Wrist Bands (Sea-Bands)
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Sue Ryder Care