Clinical trials: Palliative Care, Patient Care
End-of-life, Diabetes
Diabetes and Palliative Care
Diabetes prevalence in palliative care is 10-15%. Most hospice patients are treated with insulin. The target glucose level is high in order to decrease the risk of hypoglycemia.
- Conditions
- End-of-life, Diabetes, Terminal Cancer
- Trial name
- DIAPAL (NCT02742701)
- Testing
- diagnosis
- Volunteers
- 180 people
- Sponsor
- Maison Médicale Jeanne Garnier
Non-small Cell Lung Cancer, Small Cell Lung Cancer
Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies
The purpose of this study is to compare two types of care - standard oncology care and standard oncology care with early palliative care (started soon after diagnosis) to see which is better for improving the experience of…
- Conditions
- Non-small Cell Lung Cancer, Small Cell Lung Cancer, Mesothelioma, Esophageal Cancer
- Trial name
- NCT01401907
- Testing
- early palliative care
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- Massachusetts General Hospital
Dementia
Palliative Care at Home for Dementia
The proposed project is a randomized controlled trial of a new home-based palliative care program for adults with advanced dementia and their caregivers within the Mount Sinai Health System.
- Trial name
- NCT03798327
- Testing
- Home Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Solid Tumor, Adult, Metastasis
Clinical Nurse Specialist Led Early Palliative Survivorship Care for Patients With Advanced Cancer
The purpose of the randomized control trial is to estimate the effect of an oncology clinical nurse specialist-led early intervention multidisciplinary approach to palliative and survivorship care within two previously identified…
- Trial name
- NCT05947695
- Testing
- Palliative and Survivorship Care Model
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Good Samaritan Hospital Medical Center, New York
Hepatocellular Carcinoma, CHILD B
Palliative Treatment of Hepatocellular Carcinoma in Patient With CHILD B Cirrhosis
The incidence of Hepatocellular Carcinoma (HCC) is currently increasing in Europe and in France and about 2 / 3 of patients, are not eligible for curative treatment at the time of diagnosis.
- Trial name
- PRODIGE 21 (NCT01357486)
- Testing
- sorafenib, Pravastatin, Sorafenib + Pravastatin
- Where
- 35 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Bordeaux
End of Life Care, Liver Cirrhosis
Palliative Care for Patients With Liver Cirrhosis
Background: Patients with liver cirrhosis rarely receive palliative care although the Danish Health Authorities and WHO recommend it.
- Conditions
- End of Life Care, Liver Cirrhosis, Nurse-Patient Relations, Quality of Life
- Trial name
- LiverCare (NCT05431946)
- Testing
- Advance Care Planning and the consequent actions
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Palliative Care
Evaluation of an Intervention Designed to Enhance the Quality of Decision Support Provided to Patients Making Decisions About End-of-life Place of Care
Most dying cancer patients would prefer a home death yet die in an institution. Patients can experience uncertainty when weighing practical considerations, concern for others, and their personal ratings about the desirability and…
- Trial name
- NCT00614003
- Testing
- Decision support skills building Intervention
- Where
- 5 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Home Care Services, Hospital-Based, Frailty
Rockwood Frailty Index and Survival in Hospital-at-Home Patients
Frailty is a key determinant of prognosis in older adults with complex chronic conditions and in palliative care settings. The Rockwood Frailty Index (RFI), based on the accumulation of health deficits, has demonstrated…
- Conditions
- Home Care Services, Hospital-Based, Frailty, Mortality, Palliative Care
- Trial name
- DOMMOR (NCT07529470)
- Testing
- Patients identified and followed in this cohort received scheduled supportive telephone calls every two weeks if classified in the oncologic palliative care group, and once monthly in the case of comp
- Where
- Spain
- Volunteers
- 2,610 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer
Tier Palliative Care For Patients With Advanced Heart Failure or Cancer
TIER-PC is an adaptive model of delivering palliative care that provides the right level of care to the right patients at the right time.
- Conditions
- Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer, Advanced Lung Cancer, Advanced Triple Negative Breast Cancer
- Trial name
- TIER-PC (NCT07391956)
- Testing
- Tier-Palliative Care, Community Health Worker
- Where
- 5 sites in United States
- Volunteers
- 400 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Leukemia, Acute, AML, Adult
Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDS
The purpose of this study is to estimate the potential benefit of early and continued palliative care (PC) consultation on end of life issues.
- Conditions
- Leukemia, Acute, AML, Adult, ALL, Adult, Myelodysplastic Syndromes
- Trial name
- NCT04482894
- Testing
- Palliative Care Visits
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Virginia
Cancer Pain
A Novel mHealth Approach to Assess and Manage Palliative Care Needs for Cancer Patients in Kigali
Palliative care is an approach that improves the quality of life of patients and their families facing the problem associated with life-threatening illness such as cancer, through the prevention and relief of suffering by means…
- Trial name
- NCT03367637
- Testing
- Standard palliative care, Smart Phone based symptom evaluation application
- Where
- Rwanda
- Sponsor
- Massachusetts General Hospital
Heart Failure
Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care
There is evidence for the effectiveness and feasibility of the individual components of TIER-HF-PC, however there is a need to test how these individual components interact to allow the researchers to deliver TIER-HF-PC as a…
- Trial name
- TIER-HF-PC (NCT06244953)
- Testing
- TIER-HF-PC, Usual Care
- Where
- 4 sites in Singapore
- Volunteers
- 240 people
- Sponsor
- National Cancer Centre, Singapore
Depression
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations.
- Trial name
- KETAPAL (NCT02783430)
- Testing
- Ketamine, Milnacipran
- Where
- 9 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Pancreas Cancer
Integrating Palliative Care and Modern Palliative Care Tools Into the Care of Patients With Pancreas Cancer
The main purpose of this study is to evaluate the acceptance by patients with metastatic pancreas cancer of integrating palliative care with usual cancer treatment.
- Trial name
- iPC3 (NCT01784081)
- Testing
- Palliative care with decision aids
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cancer, Advanced
The Integrated Support and Palliative in Cancer Day-care Hospital for Patients With Advanced Cancers: Impact on Quality of Life, Care Pathways and Support for Caregivers (HDJ-SPI)
The main objective is to show the impact on the quality of life (QoL) for adults patients with advanced cancer managed in day hospital of integrated palliative care of cancer center (HDJ-SPI).
- Trial name
- NCT04604873
- Testing
- Hospital day care follow-up
- Where
- 6 sites in France
- Volunteers
- 144 people
- Sponsor
- Institut Curie
Pancreas Cancer
Tumor Registry Pancreatic Cancer
The registry aims to collect and analyse information on the antineoplastic treatment of patients with unresectable locally advanced or metastatic pancreatic cancer, treated in palliative intention (cohort 1) and patients with…
- Trial name
- AMETHYST (NCT02089269)
- Where
- Germany
- Volunteers
- 2,325 people
- Sponsor
- iOMEDICO AG
Advanced Cancers
Patient-Reported Outcomes-Based Palliative and Hospice Care Practice: A Usability Study
The goal of this research study is to learn if palliative care patients or caregivers, and palliative care physicians or nurses can use a computer program designed to provide information about the symptoms and overall health of…
- Trial name
- NCT01024166
- Testing
- Questionnaire and Review Session
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Advanced Malignant Neoplasm, Delirium
Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer
This randomized phase II/III trial studies how well haloperidol with or without chlorpromazine works in treating delirium in patients with cancer that has spread to other parts of the body or has come back.
- Conditions
- Advanced Malignant Neoplasm, Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm
- Trial name
- NCT03021486
- Testing
- Chlorpromazine, Haloperidol, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- M.D. Anderson Cancer Center
Pain Intractable, Delirium
Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients
Cancer patients with very difficult to control symptoms at the Abbotsford (AC) and Fraser Valley (FVC) Cancer Centers are referred and admitted to the Tertiary Palliative Care Units at the Abbotsford Regional Hospital and Cancer…
- Conditions
- Pain Intractable, Delirium, Dyspnea, Nausea
- Trial name
- NCT01687751
- Testing
- Dexmedetomidine, Midazolam
- Where
- Canada
- Sponsor
- Fraser Health
Advanced Lung Cancer, Non-Small Cell Lung Cancer
Family-Supported Palliative Care in Advanced Lung Cancer
This study aims to evaluate the clinical effectiveness and ethical implications of a family-supported palliative care model in patients with advanced lung cancer.
- Conditions
- Advanced Lung Cancer, Non-Small Cell Lung Cancer, Lung Neoplasms
- Trial name
- FSPC-LC (NCT07490639)
- Testing
- Family-Supported Palliative Care, Routine Nursing Care
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shanxi Province Cancer Hospital