Clinical trials: Palliative Care, Patient Care
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Leukemia, Childhood, Solid Tumor, Childhood
Observational MyPal-Child Study on the ePRO-based Early Palliative Care Digital System in Paediatric Oncology Patients
The main aim of the study is the evaluation of the feasibility of comprehensive service which has been developed while considering patient-orientated needs.
- Trial name
- MyPal4Kids (NCT04381221)
- Where
- 3 sites in Czechia, Germany
- Volunteers
- 100 people
- Sponsor
- Centre for Research and Technology Hellas
Cancer Disease, Palliative Therapy
Assessment of Disease Burden and Palliative Care Needs of Patients During the Course of Incurable Cancer Disease
The aim of this non-investigational study is to determine the symptoms and disease burden at the time point of diagnosis and in the further course of an incurable cancer disease.
- Trial name
- APM-Project (NCT02751723)
- Testing
- validated questionnaires
- Where
- 21 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Florian Lordick, MD
Oral Complication, Cancer
Oral Assessment of Symptoms in Advanced Cancer
Observational study of prevalence of oral symptoms in patients with advanced cancer using a novel questionnaire ("Oral symptom assessment scale")
- Trial name
- OASis (NCT04404920)
- Testing
- Questionnaire
- Where
- 11 sites in United Kingdom
- Volunteers
- 253 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Psychological Stress, Palliative Care
Visual Art Therapy on Caregiver Burden
This study aims to determine the effect of Zentangle practice on perceived caregiver burden, stress levels, and burnout among family caregivers of patients receiving palliative care.
- Conditions
- Psychological Stress, Palliative Care, Family Caregivers
- Trial name
- Visual art (NCT07702682)
- Testing
- Visual arts design training program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Quality of Life
Pilot Study of Living With Hope Program
Hope is important to palliative home care patients. Our research team has developed a Living with Hope Program that has been found to increase hope and quality of life in older persons with advanced cancer.
- Trial name
- NCT01697982
- Testing
- Living with Hope Program, LWH film
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Alberta
Demoralization
Demoralization Among Palliative Care Patients and Their Family Caregivers in Hong Kong: A Pilot Study
This study aims to explore the prevalence of demoralization among palliative care patients and family caregivers in Hong Kong and examines psychosocial factors associated with demoralization.
- Trial name
- NCT04006327
- Testing
- No intervention will be provided as this study is a cross-sectional observational study.
- Where
- Hong Kong
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ketamine, Refractory Cancer Pain
Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients
To establish the role of ketamine in hospitalized terminally ill cancer patients with refractory cancer pain, using continuous intravenous infusion of ketamine
- Trial name
- CIVIK (NCT03362073)
- Testing
- Ketamine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital
Palliative Patients, Terminal Malignant Tumors
Effect of Breathing Exercises on Pain, Dyspnea, and Function in Terminal-Stage Cancer Patients
This study aims to evaluate the effects of supervised breathing exercises on pain, dyspnea, and functionality in terminal-stage cancer patients receiving palliative care.
- Conditions
- Palliative Patients, Terminal Malignant Tumors, Breathing Techniques
- Trial name
- NCT07164352
- Testing
- Breathing Exercises, Informational Brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Atlas University
Palliative Medicine
A Multidimensional Strategy to Improve Quality of Life of Patients With Multiple Symptoms and Palliative Care Needs
A nationwide, cross-sectional study, to determine the prevalence of symptoms of patients in the palliative phase in various care settings will be performed within a set period of two weeks in September 2018 and two weeks in…
- Trial name
- MuSt-PC (NCT03665168)
- Where
- Netherlands
- Volunteers
- 659 people
- Sponsor
- University Medical Center Groningen
Palliative Care, Dyspnea
The Effect of Acupressure on the Management of Dyspnea
Dyspnea can develop at any stage of the disease, but it is more common in the last period of life. Complementary and integrative methods used for dyspnea symptoms include acupuncture, acupressure, visualization techniques, herbal…
- Trial name
- NCT05884450
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Advance Care Planning, Palliative Care
Palliative Care Educator
The investigators propose to conduct a stepped wedge cluster randomized trial of an advance care planning (ACP) educator-led intervention among hospitalized patients aged 65 and over, or any patient with Alzheimer's Disease and…
- Conditions
- Advance Care Planning, Palliative Care, Alzheimer's Disease and Related Dementias, Doctor-patient Communication
- Trial name
- VIDEO-PCE (NCT04857060)
- Testing
- ACP Educator led, video assisted discussion
- Where
- 2 sites in United States
- Volunteers
- 11,174 people
- Sponsor
- Tufts Medical Center
Heart Failure
ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore
To pilot a culturally adapted version of ENABLE (6-month program) for Heart Failure (HF) patients and caregivers in the inpatient and outpatient setting in Singapore.
- Trial name
- ENABLE-HF-SG (NCT05211882)
- Testing
- Immediate ENABLE nurse coaching, on top of usual care, Usual Care
- Where
- 2 sites in Singapore
- Volunteers
- 125 people
- Sponsor
- National Cancer Centre, Singapore
Terminal Illness, Terminal Cancer
DigiPall; a Trial of Digital Patient Reported Outcome and Biomarker Monitoring in Palliative Care
The aim of this study is to test if a system consisting of a wearable device measuring heartbeats and steps, together with daily communication with a chatbot on the smartphone asking the patients about their symptoms and giving…
- Trial name
- NCT06615349
- Testing
- DigiPall
- Where
- Switzerland
- Volunteers
- 382 people
- Sponsor
- David Blum
Metastatic Cancer
A Trial Investigating the Effect of Specialised Palliative Care on Symptoms, Survival, Economical Factors and Satisfaction
Specialised palliative care (SPC) seeks to relieve suffering and improve quality of life in patients with a life threatening disease such as advanced cancer. Many patients with advanced cancer are not in contact with SPC.
- Trial name
- DanPaCT (NCT01348048)
- Testing
- Specialised palliative care (SPC)
- Where
- 6 sites in Denmark
- Volunteers
- 306 people
- Sponsor
- Bispebjerg Hospital
Oncology
STEP2 vs. Routine Early Palliative Care: Randomized Noninferiority Trial
Palliative care aims to improve quality of life for people with advanced illness, and early palliative care (EPC) has been shown to benefit patients with late-stage cancer.
- Trial name
- STEP2 RNT (NCT07446660)
- Testing
- Virtual and in-person Symptom screening with Targeted Early Palliative care (STEP2), Early Palliative Care (EPC)
- Where
- Canada
- Volunteers
- 652 people
- Sponsor
- University Health Network, Toronto
Dementia
Palliative Care for Patients With Dementia
A multi-site, single-blinded, parallel, randomized-controlled trial to evaluate the effectiveness of a novel model of in-home palliative care for dementia patients and their family caregivers.
- Trial name
- NCT05749146
- Testing
- Home Palliative Care
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pulmonary Disease, COPD
Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to evaluate a multifaceted intervention to improve the quality of end-of-life communication between patients with COPD and their primary care providers using information about patients preferences for…
- Conditions
- Pulmonary Disease, COPD, Chronic Bronchitis, Emphysema
- Trial name
- NCT00106080
- Testing
- Audit and Feedback
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- VA Office of Research and Development
Cancer
Specialized Palliative Telemedicine for Patients with Advanced Cancer
Specialized palliative care (SPC) plays an important role in providing patient-centered care and support to informal caregiver, besides establishing/intensifying/coordinating collaboration with primary and secondary health care…
- Trial name
- TeleSPC (NCT05231070)
- Testing
- TeleSPC
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Death, Pain
Intervention to Improve Care at Life's End
The BEACON trial (Best Practices for End-of-Life Care for Our Nations' Veterans) was a six-site implementation study to evaluate a multi-component, education-based intervention to improve the quality of end-of-life care provided…
- Conditions
- Death, Pain, Dyspnea
- Trial name
- BEACON (NCT00234286)
- Testing
- Comfort care education intervention
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- US Department of Veterans Affairs