Clinical trials: Palliative Care, Patient Care
Critically Ill
Managing Acute Pain in Critically Ill Non-communicative Palliative Care Patients
The purpose of this project is to test an innovative method for managing pain in acutely ill hospitalized patients who are not able to report their pain verbally to health care professionals.
- Trial name
- NCT02127086
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- University of Maryland, Baltimore
Palliative Care, Decision Making
Feasibility Of An Advanced Care Decision Aid Among Patients And Physicians_Matlock
The investigators propose an evaluation of an end of life patient decision aid (EOL-PtDA) developed by the Foundation for Informed Medical Decision Making using the RE-AIM (Reach Effectiveness, Adoption, Implementation, and…
- Conditions
- Palliative Care, Decision Making, Decision Support Techniques, Decision Support Systems, Clinical
- Trial name
- NCT01190488
- Testing
- End-of-Life / Advanced Care Decision Aid, Active Comparator
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Advanced Cancer
Adjunctive Effect of Acupuncture for Advanced Cancer Patients With Palliative Care: a Three-arm Randomized Trial
The proposed study aims to evaluate the adjunctive effect of MA with standard care (ASC) for relieving cancer-related symptoms in a collaborative model of palliative care compared to sham MA plus standard care (SSC) or standard…
- Trial name
- NCT04398875
- Testing
- Acupuncture and standard care (ASC), Standard care (SC)
- Volunteers
- 120 people
- Sponsor
- The University of Hong Kong
Cancer
Psychosocial Support for Cancer Patients
This is an international, 3-site trial (Winnipeg Canada, MSKCC NYC, Perth Australia) accruing 120 patients per site (120x3). The purpose of this study is to compare two types of counseling for cancer patients: "Dignity…
- Trial name
- NCT00133965
- Testing
- Dignity Psychotherapy, Supportive Psychotherapy, Standard Palliative Care
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breakthrough Pain
Quality of Life Study in Patients With Cancer Breakthrough Pain Treated in Palliative Care Units
Patients treated in Palliative Care Units are potentially fragile patients, especially in our case, which are cancer patients. The management of these patients is usually done from experience, because these patients rarely meet…
- Trial name
- CAVIDIOPAL (NCT02840500)
- Testing
- No intervention
- Where
- 10 sites in Spain
- Volunteers
- 101 people
- Sponsor
- Angelini Farmacéutica
Heart Failure, Pulmonary Disease, Chronic Obstructive
Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD
Many Veterans living with heart failure or chronic obstructive pulmonary disease (COPD) experience significant symptoms - such as breathlessness, fatigue, depression, and anxiety -that reduce their quality of life.
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Interstitial Lung Disease
- Trial name
- VITALVET:ADAPT (NCT07714252)
- Testing
- Virtual Nurse and Social Worker Palliative Care Team, Enhanced Implementation Support, Standard Implementation Support
- Where
- 7 sites in United States
- Volunteers
- 420 people
- Sponsor
- VA Office of Research and Development
Cancer, Pain
Corticosteroids for Cancer Pain
Study hypothesis: corticosteroids are effective for pain in cancer patients. We will perform a double-blind, randomized, placebo-controlled multicentre trial evaluating the effect of Methylprednisolone 16 mg twice daily in cancer…
- Trial name
- NCT00676936
- Testing
- Methylprednisolone
- Where
- 6 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Norwegian University of Science and Technology
Palliative Care, Cancer
Mobile Health Application for Family Caregivers in Home Palliative Care
Family caregivers play a central role in providing daily care for patients receiving home palliative care. However, caregiving responsibilities may lead to increased burden, stress, and difficulties in symptom management and care…
- Conditions
- Palliative Care, Cancer, Caregiver
- Trial name
- CARE-Mobile (NCT07654998)
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kutahya Health Sciences University
Advanced Cancer
Study of Palliative Care Intervention for Advanced Cancer Patients and Their Caregivers -Educate Nurture Advise Before Life Ends (ENABLE III)
ENABLE III is a randomized clinical trial that evaluates a phone-based palliative care intervention designed to improve quality of life, mood, and symptom management for patients with an advanced stage cancer and their…
- Trial name
- ENABLE III (NCT01245621)
- Testing
- Later entry group, Early palliative care intervention
- Where
- 7 sites in United States
- Volunteers
- 360 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
Depression
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations.
- Trial name
- KETAPAL (NCT02783430)
- Testing
- Ketamine, Milnacipran
- Where
- 9 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Constipation, Opioid-Induced
Prevention of Opioid-induced Constipation in Patients With Advanced Cancer
More than 70% of patients with cancer in the palliative phase have pain that often requires treatment with opioids (morphine-like agents). Constipation occurs in 59% of patients treated with opioids.
- Trial name
- OMAMA (NCT05216328)
- Testing
- Macrogol Only Product in Oral Dose Form, Magnesium hydroxide 724mg
- Where
- 13 sites in Netherlands
- Volunteers
- 258 people
- Sponsor
- Amsterdam UMC, location VUmc
Hematopoietic Cell Transplant, Hematologic Malignancy
Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation
Primary PC - or training HCT clinicians to deliver PC domains as part of routine practice - is an alternative model of supportive care. We have developed Sentinel, a primary PC intervention for HCT clinicians and patients.
- Trial name
- Primary PC HCT (NCT06676852)
- Testing
- Primary palliative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Palliative Care, Micronutrients
Micronutrient Status in Pediatric Palliative Care
The goal of this observational study is to determine the micronutrient levels in patients in the Pediatric Palliative Care Clinic.
- Conditions
- Palliative Care, Micronutrients, Pediatric
- Trial name
- NCT06146452
- Testing
- Not
- Where
- Turkey (Türkiye)
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Acute Coronary Syndrome, Congestive Cardiac Failure
Palliative Care for Patients With Advanced Heart Disease
Patients admitted as an unscheduled hospital admission with either a acute heart failure syndrome (ACF) or acute coronary syndrome (ACS) will be eligible if their 6-12 month mortality risk is estimated to be 20% or greater at the…
- Conditions
- Acute Coronary Syndrome, Congestive Cardiac Failure, Palliative Care
- Trial name
- FLAME (NCT02302014)
- Testing
- Palliative Care Intervention
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Stage IV Non-small Cell Lung Cancer, Targeted Therapy
Patient-centered, Optimal Integration of Survivorship and Palliative Care
The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC).
- Conditions
- Stage IV Non-small Cell Lung Cancer, Targeted Therapy, Nonsmall Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT04900935
- Testing
- POISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Cancer, Self Efficacy
The Effect of Telephone Symptom Triage Protocols in Patients With Cancer Therapy (TeleTRIAGE)
The purpose of this study was to evaluate the effect of telephone symptom triage protocols on symptom management, quality of life and self-maintenance in patients with cancer who applied systemic treatment.
- Trial name
- NCT04162717
- Testing
- The Effect of Telephone Symptom Triage Protocols on Symptom Management, Quality of Life and Self-Care Maintenance in Patients with Cancer Who Applied Systemic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Heart Failure, Nursing Care
Effect of Mindful Breathing in Patient With Heart Failure:
The aim of this study was to investigate the effect of mindful breathing on symptom status and clinical parameters in patients with heart failure.
- Conditions
- Heart Failure, Nursing Care, Symptom Management, Mindful Breathing Meditation
- Trial name
- NCT07824687
- Testing
- Mindful Breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ankara Medipol University
Severe COPD
Advance Care Planning Individualised Approach and Research Projec
The study will investigate the effect of a palliative approach in the out-patient management of patients with COPD.
- Trial name
- AIR (NCT03915743)
- Testing
- palliative care
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Herlev and Gentofte Hospital