Clinical trials: Palliative Care, Patient Care
ICU, Comfort
Comfort Care Bundle
Intensive care units (ICUs) are specialized units where numerous complex treatment and care procedures are applied. In these units, critically ill patients are exposed to stressful conditions and experience significant pain and…
- Conditions
- ICU, Comfort, Bundle Care, Nursing Care
- Trial name
- NCT07366021
- Testing
- Comfort Care Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Pediatric Neoplasm, Quality of Life
The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology
Over 50% of children dying from cancer still suffer from symptoms that could be effectively alleviated. The purpose of the Pediatric Quality of Life and Evaluation of Symptoms Technology (PediQUEST) Study was to evaluate whether…
- Conditions
- Pediatric Neoplasm, Quality of Life, Outcome Assessment, Palliative Care
- Trial name
- NCT01838564
- Testing
- Routine Data collection, Feedback of patient-reported outcomes
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Dana-Farber Cancer Institute
Cancer
Pilot Study of the SPaRK (Supportive and Palliative Care Review Kit) Model of Care for Advanced Cancer Patients Who Have an Unplanned Admission to Singapore General Hospital
Advanced cancer patients have a poor quality of life and a high rate of unplanned hospital admissions. Palliative care has been shown to improve patient outcomes such as quality of life and symptom burden.
- Trial name
- SPaRK (NCT02559336)
- Testing
- Integrated palliative oncology care
- Where
- Singapore
- Volunteers
- 865 people
- Sponsor
- National Cancer Centre, Singapore
Pancreatic Neoplasm
Palliative Care Consultation to Improve Communication for Patients Considering Surgery for a Pancreatic Neoplasm
This clinical trial evaluates a palliative care consultation for improving communication between providers and patients considering surgery for a pancreatic neoplasm.
- Trial name
- NCT06545344
- Testing
- Best Practice, Palliative Care Consultation, Survey Administration
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Sustaining Home Heart Failure Palliative Care in Rural Appalachia
The aim of this mixed methods randomized controlled trial is to test the integrated nurse-led intervention bundle for family home care management of end-stage heart failure and palliative care in rural Appalachia.
- Trial name
- NCT06791850
- Testing
- HF-FamPALhomeCARE
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- West Virginia University
Cachexia, Cancer
Impact of Nutritional Intervention in Indian Female Cancer Cachexia Patients
The main aim of the study is to assess the effectiveness of tailored nutritional intervention in delaying the progression of cachexia to refractory cachexia in adult female cancer patients.
- Trial name
- NCT02350855
- Testing
- Improved Atta, Nutritional counseling, Physical activity counseling
- Where
- 2 sites in India, United Kingdom
- Volunteers
- 62 people
- Sponsor
- University of Westminster
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Metastatic Solid Tumor Cancers, Locally Advanced Solid Tumor Cancers
Investigating the Impact of Proactive Palliative Care
This study will test whether adding personalized supportive care to medical treatment on a clinical trial affects the study participants' ability and desire to discuss their symptoms, their concerns about the future, and their…
- Trial name
- NCT03667378
- Testing
- Expectations Survey (CanCORS), Values Survey (Serious Illness Care Program), Functional Assessment of Cancer Therapy-General (FACT-G)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
Assessment of the Reasons for Accepting or Refusing Early Palliative Care
This is a prospective, multicentre study, considered as " non-RIPH ("Recherche n'Impliquant pas la Personne Humaine - Research that does not involve humans ".
- Trial name
- PALPHA-1 (NCT04717440)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Leon Berard
Caregiver Burden
ACT-CSP for Family Caregivers of Palliative Care Patients
The goal of the study is to test the feasibility, acceptability and preliminary efficacy of an acceptance and commitment therapy for supporting caregiver programme (ACT-CSP) on reduction of caregiver burden, anxiety and…
- Trial name
- NCT06221189
- Testing
- ACT-CSP
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cancer
Evaluation of the Therapeutic Approach of Aromatherapy by Olfaction of Essential Oils in Association With Hypnosis in the Management of Patients Followed for Cancer
Patients having the following gestures (blood test, change of dressing for cancerous lesion and complete toilet in bed) will be identified by the team of the medical oncology department.
- Trial name
- HYPNO-AROMA (NCT05714995)
- Testing
- hypnosis, Hypnosis with aromatherapy
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Cancer
Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients
RATIONALE: Palliative care may help patients with advanced cancer live more comfortably. PURPOSE: This randomized clinical trial is studying an early intervention palliative care program to see how well it works compared to a…
- Trial name
- NCT00253383
- Testing
- counseling intervention, educational intervention, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Constipation, Opioid-Induced
Prevention of Opioid-induced Constipation in Patients With Advanced Cancer
More than 70% of patients with cancer in the palliative phase have pain that often requires treatment with opioids (morphine-like agents). Constipation occurs in 59% of patients treated with opioids.
- Trial name
- OMAMA (NCT05216328)
- Testing
- Macrogol Only Product in Oral Dose Form, Magnesium hydroxide 724mg
- Where
- 13 sites in Netherlands
- Volunteers
- 258 people
- Sponsor
- Amsterdam UMC, location VUmc
Palliative Care
Improvement of Support to Caregivers of Cancer Patients in Basic Palliative Care at Home
The aim of the project is to evaluate the use of the caregiver-led 'CSNAT intervention' to identify, prioritize and address support needs among caregivers of cancer patients who are starting in basic palliative care at home in…
- Trial name
- PiH (NCT03548012)
- Testing
- The Carer Support Needs Assessment Tool (CSNAT) intervention
- Where
- 10 sites in Denmark
- Volunteers
- 135 people
- Sponsor
- Bispebjerg Hospital
Pediatric Cancer
Evaluating Supportive Care for Children With Cancer: A Multi-Institutional Survey Study of Pediatric Oncology Patients and Parents
Background: Palliative care, also known as comfort care, is intended to keep a patient comfortable by focusing on pain and symptom management to improve quality of life.
- Trial name
- NCT01273194
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Advanced Cancer
Adjunctive Effect of Acupuncture for Advanced Cancer Patients With Palliative Care: a Three-arm Randomized Trial
The proposed study aims to evaluate the adjunctive effect of MA with standard care (ASC) for relieving cancer-related symptoms in a collaborative model of palliative care compared to sham MA plus standard care (SSC) or standard…
- Trial name
- NCT04398875
- Testing
- Acupuncture and standard care (ASC), Standard care (SC)
- Volunteers
- 120 people
- Sponsor
- The University of Hong Kong
Dyspnea, Palliative Care
"Turkish Validation of the Respiratory Distress Observation Scale in Palliative Care"
Dyspnea is a subjective experience influenced by physiological, cognitive, behavioral, and sociocultural factors. While self-reported scales are commonly used to assess dyspnea severity, they are unsuitable for patients unable to…
- Conditions
- Dyspnea, Palliative Care, Reliability and Validity
- Trial name
- NCT06922292
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istinye University
Advanced Cancers
Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer
This randomized phase II trial studies how well haloperidol with or without lorazepam works in reducing confusion, disorientation, and inability to think or remember clearly (delirium) in patients with cancer that has spread to…
- Trial name
- NCT01949662
- Testing
- Lorazepam, Haloperidol decanoate, Questionnaires
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- M.D. Anderson Cancer Center
Illness Terminal
Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy
The Conscious Dying/Conscious Living study will investigate the effect of KAP (ketamine-assisted psychotherapy) on individuals with terminal illness at five separate geographic locations.
- Trial name
- KRF-EOL (NCT05214417)
- Testing
- Ketamine Injectable Solution, Naturalistic Control
- Volunteers
- 120 people
- Sponsor
- The Ketamine Research Foundation
Depressive Symptoms, Depression, Anxiety
Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness
Psychological and existential distress are a common cause of suffering among patients nearing the end of life, and a major reason for requesting medical aid in dying.
- Conditions
- Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness
- Trial name
- NCT04257227
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Hospital Research Institute