Clinical trials: Palliative Care
Primary Caregiver Readiness for Care and Psychological Resilience in Palliative Care
Nurse-Led AI-Supported Psychosocial Support for Palliative Caregivers
Primary caregivers of palliative care patients assume responsibility for meeting the patient's needs, monitoring symptoms, maintaining care practices, and managing changing needs.
- Trial name
- NCT07799389
- Testing
- Nurse-Led, Generative AI-Supported Individualized Psychosocial Support Program, Routine Care and Information
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Carers, Palliative Care
A Pilot Effectiveness and Implementation Trial of CSNAT-I in Hong Kong
In this hybrid Type 1 effectiveness-implementation pilot randomized controlled trial, 60 caregivers will be randomized into either the CSNAT-I group or usual care.
- Conditions
- Carers, Palliative Care, Needs Assessment, Supportive Care
- Trial name
- NCT07193433
- Testing
- CSNAT-I
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Metastasis, Locally Advanced Solid Tumor
Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients
XRD-0394 is a novel, potent, oral, small molecule dual inhibitor of ataxia telangiectasia mutated kinase (ATM) and deoxyribonucleic acid (DNA)-dependent protein kinase (DNA-PK) that has selectivity compared with other…
- Conditions
- Metastasis, Locally Advanced Solid Tumor, Recurrent Cancer
- Trial name
- NCT05002140
- Testing
- XRD-0394, Palliative radiotherapy
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- XRad Therapeutics Inc
Cancer
Integral Attention Program With or Without Palliative Chemotherapy in Advanced Cancer Patients
The purpose of this clinical trial is to compare a non-pharmaceutical intervention (Integral Attention Program or PAI) versus standard palliative chemotherapy treatment plus PAI in patients with advanced cancer who have already…
- Trial name
- PAI (NCT01949974)
- Testing
- Standard Palliative Chemotherapy, Integral Attention Program (PAI)
- Where
- 3 sites in Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Dyspnea, Respiratory Insufficiency
Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced Disease
Episodic breathlessness is a common and distressing symptom in patients with advanced disease such as cancer, chronic obstructive pulmonary disease (COPD) and chronic heart failure.
- Conditions
- Dyspnea, Respiratory Insufficiency, Neoplasms, Pulmonary Disease, Chronic Obstructive
- Trial name
- CoBeMEB (NCT04630743)
- Testing
- Cognitive and Behavioral intervention for the Management of Episodic Breathlessness
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Cologne
Severe COPD
Advance Care Planning Individualised Approach and Research Projec
The study will investigate the effect of a palliative approach in the out-patient management of patients with COPD.
- Trial name
- AIR (NCT03915743)
- Testing
- palliative care
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Herlev and Gentofte Hospital
Palliative Care
Prediction of Hospital Readmissions in SAPV (Specialised Home Palliative Care) Patients
Specialised outpatient palliative care (German: Spezialisierte ambulante Palliativversorgung, abbreviation: SAPV) aims to support incurably ill or dying people spending their last lifetime at home.
- Trial name
- PRePP (NCT05082389)
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Advanced Incurable Cancer
Romanian-Swiss Research Programme IZERZO
Palliative Care procedures should be integrated early in the course of disease of patients with advanced incurable cancer. With this study, where the investigators follow adult patients with incurable cancer over 6 months or…
- Trial name
- IZERZO (NCT03237884)
- Where
- 2 sites in Romania, Switzerland
- Volunteers
- 308 people
- Sponsor
- Cantonal Hospital of St. Gallen
Hemorrhage
Predictive Factors for Major Bleeding Risk in Patients Admitted in a Palliative Care Unit
Even if most patients in palliative care units presented with well-recognized risks factors of venous thromboembolism (VTE) (eg: active cancer, bed rest, previous history of venous thrombosis), the incidence of VTE in palliative…
- Trial name
- RHESO (NCT01056978)
- Where
- 20 sites in France
- Volunteers
- 1,230 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Advanced Cancer, Terminal Malignant Tumors
Nurses' Competence and Role in Survival Prediction and Prognostic Communication
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms.
- Conditions
- Advanced Cancer, Terminal Malignant Tumors, Hospices
- Trial name
- NCT06962553
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nurse-Patient Relations, Psychology, Social
Meaning-Centered Psychotherapy at Home
The purpose of this study is to train nurses from the VNS Health Visiting Nurse Service to deliver Meaning-Centered Psychotherapy for Palliative Care Patients (MCP-PC) to homebound people, and to evaluate how effective MCP-PC is…
- Trial name
- NCT05495737
- Testing
- Meaning-Centered Psychotherapy/MCP-PC Training, Meaning-Centered Psychotherapy/MCP-PC, Treatment As Usual/TAU
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Leukaemia in Relapse
Early Palliative Care in Patient With Acute Leukaemia
Several studies have shown that patients with acute leukemia have many symptoms during disease These symptoms decrease the quality of life and may even appear or worsen other symptoms such as depression Several studies point to…
- Trial name
- Pablo Hemato (NCT02631811)
- Testing
- Supportive /palliative care intervention
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Hospices Civils de Lyon
Bone Cancer Metastatic
A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy
The objective of this study is to evaluate real-world outcomes (e.g., pain, patient reported outcomes, skeletal related events, healthcare utilization, etc.) in patients treated with both percutaneous ablation and palliative…
- Trial name
- TRIBUTE (NCT06859801)
- Testing
- Percutaneous Ablation, Radiation Therapy
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Society of Interventional Oncology
Liver Cancer
Sorafenib Tosylate With or Without Pravastatin in Treating Patients With Liver Cancer and Cirrhosis
RATIONALE: Sorafenib tosylate and pravastatin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT01075555
- Testing
- pravastatin sodium, sorafenib tosylate
- Where
- France
- Volunteers
- 323 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Hormone Receptor Positive Breast Cancer
Telehealth Intervention for Symptom Management and Adherence to Adjuvant Endocrine Therapy
The goal of this study is to demonstrate the efficacy of an evidence-based, small-group, telehealth intervention ('STRIDE') for improving patients' ability to cope with side effects from adjuvant endocrine therapy (AET) and…
- Trial name
- STRIDE (NCT07759947)
- Testing
- STRIDE, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Chronically Ill
Hope Promotion Program: Effectiveness in Palliative Patients
This study aims to: I. Develop and pilot test the effectiveness of a Hope Promotion Program compared with the standard treatment protocol, in hope, comfort and quality of life, based on a population of palliative patients…
- Trial name
- HPP (NCT02723799)
- Testing
- Hope Promotion Program (HPP), Standard Treatment Protocol
- Volunteers
- 26 people
- Sponsor
- Instituto Politécnico de Leiria
Lung Cancer
Study of Stepped Palliative Care in Patients With Advanced Lung Cancer DF/HCC SOCIAL-BEHAVIORAL RESERACH PROTOCOL
This research study is evaluating a new way to provide palliative care to patients who have recently been diagnosed with lung cancer. .
- Trial name
- NCT03220100
- Testing
- Stepped Palliative Care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Palliative Care, Primary Palliative Care
Primary Palliative Care - a Feasibility Cluster Trial
This feasibility cluster-controlled randomized trial (RCT) evaluates a complex intervention for the delivery of primary palliative care in Family Health Units (FHUs).
- Conditions
- Palliative Care, Primary Palliative Care, Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- PrimPal (NCT07737899)
- Testing
- Primary Palliative Care Complex Intervention (PrimPal)
- Where
- 2 sites in Portugal
- Volunteers
- 30 people
- Sponsor
- University of Coimbra
Hope, Spirituality
Effects of Nursing Care Provided to Relatives of Palliative Care Patients on Caregivers' Spiritual Well-being and Hope
The aim of this study is to determine the effects of nursing care provided based on the Watson's Theory of Human Caring to the relatives of palliative care patients on caregivers' spiritual well-being and hope.
- Conditions
- Hope, Spirituality, Palliative Care
- Trial name
- NCT04415411
- Testing
- Nursing care based on the Theory of Human Caring
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Dyspnea
Interdisciplinary Approach for Refractory Dyspnoea
Dyspnoea is a very common symptom in many diseases, not only cardiorespiratory, but also renal or neurological diseases. It can be defined as " difficult, laboured and uncomfortable breathing […]. It is a subjective symptom.
- Trial name
- NCT04015817
- Testing
- paramedical and non-pharmacological services
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Ligue Pulmonaire Neuchâteloise