Clinical trials: Palliative Patients
Heart Defects, Congenital
Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation
This study is the extension of the CLARINET study [NCT00396877 -EFC5314] in neonates or infants with cyanotic congenital heart disease palliated with a systemic-to-pulmonary artery shunt.
- Trial name
- CLARINET LT (NCT00833703)
- Testing
- Clopidogrel
- Where
- 15 sites in United States, Brazil and 13 more
- Volunteers
- 49 people
- Sponsor
- Sanofi
Non-Small Cell Lung Cancer (NSCLC)
Vorinostat in Combination With Palliative Radiotherapy for Patients With Non-Small Cell Lung Cancer
This is a dose escalation study that will assess the safety of Vorinostat, a Histone Deacetylase (HDAC) inhibitor, in combination with palliative radiotherapy in patients with advanced or metastatic Non-Small Cell Lung Cancer…
- Trial name
- NCT00821951
- Testing
- Vorinostat, Radiotherapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Yale University
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma
Registry Platform Gastric/Esophageal Cancer (SAPHIR)
The registry aims to collect and analyse information on the antineoplastic treatment of patients with metastatic esophageal, gastric or gastroesophageal junction cancer, treated in palliative intention in daily routine practice…
- Conditions
- Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Esophageal Adenocarcinoma
- Trial name
- SAPHIR (NCT04290806)
- Testing
- Routine care as per site standard
- Where
- Germany
- Volunteers
- 1,900 people
- Sponsor
- iOMEDICO AG
Carcinoma, Renal Cell
Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma Patients
The purpose of this study is to evaluate efficacy and safety of Radiofrequency ablation in metastatic renal cell carcinoma patients with primary tumor less than 5 cm before medical treatment.
- Trial name
- NCT00891475
- Testing
- Radiofrequency ablation; Interferon-alpha, Radiofrequency ablation; Sunitinib maleate, Sunitinib maleate
- Where
- Russia
- Volunteers
- 114 people
- Sponsor
- Kidney Cancer Research Bureau
Hope, Spirituality
Effects of Nursing Care Provided to Relatives of Palliative Care Patients on Caregivers' Spiritual Well-being and Hope
The aim of this study is to determine the effects of nursing care provided based on the Watson's Theory of Human Caring to the relatives of palliative care patients on caregivers' spiritual well-being and hope.
- Conditions
- Hope, Spirituality, Palliative Care
- Trial name
- NCT04415411
- Testing
- Nursing care based on the Theory of Human Caring
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Advanced Cancer
Psychosocial Intervention in Latino Patients with Advanced Cancer
Palliative Care focuses on symptom management and quality of life and helps patients with life-limiting illness match goals and preferences for care.
- Trial name
- NCT03763032
- Testing
- Counseling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Colorado, Denver
Colorectal Cancer, Metastatic Cancer
Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug or giving the drugs in different ways may kill more tumor cells.
- Trial name
- NCT00002793
- Testing
- fluorouracil, leucovorin calcium
- Where
- Germany
- Volunteers
- 336 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
This phase I/II trial studies the side effects of durvalumab, tremelimumab and hypofractionated radiation therapy in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or that has spread…
- Trial name
- NCT03522584
- Testing
- Durvalumab, Laboratory Biomarker Analysis, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Washington
Soft Tissue Sarcoma
Patient Directed Intervention to Improve the Quality of Life for Patients With Soft Tissue Sarcoma
The primary objective of the study is to compare quality of life (QoL) between patients suffering from soft tissue sarcoma, receiving a multidimensional intervention with those receiving standard treatment.
- Trial name
- YonLife (NCT02204111)
- Testing
- Intervention
- Where
- 7 sites in Germany
- Volunteers
- 77 people
- Sponsor
- GWT-TUD GmbH
Cancer
Evaluating the CAREchart@Home™ Program for Enhancing After-hours Cancer Care
The objective of the current project is to pilot the evaluation of the health and economic benefits of having online access to health information in the context of providing telemedicine support for oncology patients receiving…
- Trial name
- NCT04232709
- Testing
- Shared electronic patient record
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Women's College Hospital
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Pancreas Cancer
Tumor Registry Pancreatic Cancer
The registry aims to collect and analyse information on the antineoplastic treatment of patients with unresectable locally advanced or metastatic pancreatic cancer, treated in palliative intention (cohort 1) and patients with…
- Trial name
- AMETHYST (NCT02089269)
- Where
- Germany
- Volunteers
- 2,325 people
- Sponsor
- iOMEDICO AG
Gastroparesis
Vagus Nerve Response in Gastroparesis Patients
This study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).
- Trial name
- NCT04207996
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Demoralization
Demoralization Among Palliative Care Patients and Their Family Caregivers in Hong Kong: A Pilot Study
This study aims to explore the prevalence of demoralization among palliative care patients and family caregivers in Hong Kong and examines psychosocial factors associated with demoralization.
- Trial name
- NCT04006327
- Testing
- No intervention will be provided as this study is a cross-sectional observational study.
- Where
- Hong Kong
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pecha Kuka, Palliative Care
Pecha Kuka Method About Percutaneous Endoscopic Gastrostomy for Caregivers Who Care for Palliative Care Patients
Palliative care; It was started by Dame Cicely Saunders in the 1960s as a hospice for community-based provision. Today, palliative care is defined as care that begins with the patient's diagnosis, symptom management is carried…
- Trial name
- NCT06339723
- Testing
- Pecha Kucha
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Cancer
Caregivers' Strengths-Skills: Managing Older Cancer Patients' Symptoms
Caregiver education and training programs that specifically target caregiver informational and training needs during the survivorship period have been limited.
- Trial name
- FamCare (NCT03532061)
- Testing
- FamCare Program, Caregiver Support Group
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- New York University
Multimorbidity
Living With Multimorbidity: Care Coordination and Symptom Management Program (COORDINATE)
The goal of this clinical trial is to learn if a new care program, called the COORDINATE Program, can help older adults with two or more chronic health conditions.
- Trial name
- NCT07157982
- Testing
- COORDINATE Program, Enhanced Usual Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
COVID-19, Palliative Care
Palliative Care in Patients With COVID-19: Analysis of Costs of Hospitalization in Wards and Intensive Care Units
The confrontation of COVID-19 foreshadowed a serious crisis of scarce health resources worldwide. To assist in this confrontation, the Palliative Care Scientific Technical Core of the Clinical Hospital, School of Medicine, Sao…
- Trial name
- NCT05897229
- Testing
- Analysis of costs with patient care during hospitalization
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Palliative Care
Pilot Study Evaluating the Therapeutic Effects of Passive Exposure Virtual Reality on Pain, Anxiety, Fatigue, and Well-being in Patients With Complex Palliative Care Needs.
The EPURAVAS "Pilot Study Using Augmented and Virtual Reality to Ease Suffering in Palliative Care" study is designed to investigate a non-medication treatment for complex symptoms in palliative care.
- Trial name
- EPURAVAS (NCT07214090)
- Testing
- Transparent Augmented Reality with Real-World Video Feed Overlay (RVAT), Passive Multisensory Virtual Reality Immersion via Head-Mounted Display (RVEP)
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Cancer
Prognosis and Survival Estimates in Palliative Therapy
The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.
- Trial name
- NCT00871520
- Testing
- no specific interventions
- Where
- 3 sites in Germany
- Volunteers
- 612 people
- Sponsor
- Heinrich-Heine University, Duesseldorf