Clinical trials: Pancreas Diseases
Acute Pancreatitis, Necrosis; Pancreas, Acute (Infectious)
Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis
In acute pancreatitis, approximately 20% of the cases result in severe necrotizing pancreatitis which is associated with significant morbidity and mortality.
- Trial name
- RESOlVE (NCT04814693)
- Testing
- EndoRotor® System (Interscope, Inc., Northbridge, MA USA),, Conventional endoscopic devices (according to standards of care)
- Where
- 12 sites in United States, Denmark and 4 more
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center
Pancreatic Neoplasm, Pancreas Cancer
MSCAN: ctDNA Methylation as Prognostic and Theranostic Tool for Pancreatic Cancer
Developing a characteristic ctDNA methylation panel for pancreatic ductal adenocarcinoma and establishing an intelligent diagnostic and dynamic monitoring model based on ctDNA methylation.
- Trial name
- NCT07045571
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Yingbin Liu, MD, PhD, FACS
Pancreatic Cancer, Pancreas Disease
Artificial Intelligence in Endoscopic Ultrasound
The objective of the study is to determine if this artificial intelligence system is capable of detecting abnormalities in the pancreas that are identified by an endoscopist at endoscopic ultrasound procedures.
- Conditions
- Pancreatic Cancer, Pancreas Disease, Pancreatic Cyst
- Trial name
- NCT06564571
- Testing
- Patients undergoing endoscopic ultrasound procedures
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Orlando Health, Inc.
Pancreas Cancer, Prostate Cancer
Evaluating an Alternative Clinical Genetics Cancer Care Deliver Model
To evaluate an alternative clinical genetics cancer care delivery model, using non-genetic providers to introduce and order genetic testing. 250 prostate and 250 pancreatic patients will be recruiting.
- Conditions
- Pancreas Cancer, Prostate Cancer, Hereditary Cancer, Genetic Predisposition to Disease
- Trial name
- NCT03934606
- Testing
- Genetic testing for hereditary predisposition
- Where
- United States
- Volunteers
- 1,488 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Pancreatic Cyst, Pancreas Disease
Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer
Bio-repository to collect bio-specimens from patients with 1) pancreatic cysts and 2) patients at high risk, defined by family history and/or genetic mutations, for pancreatic cancer.
- Trial name
- NCT03260842
- Testing
- Bio-Specimen Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Stanford University
Pancreatic Diseases, Pancreas Cancer
Improvement of Care of Patients Undergoing Pancreaticoduodenectomy
The study is a randomised controlled trial comparing the effectivity and impact of epidural analgesia and wound catheter analgesia in patients undergoing pancreaticoduodenectomy.
- Trial name
- NCT04668781
- Testing
- Analgesia via epidural catheter, Analgesia via wound catheter
- Where
- Finland
- Volunteers
- 92 people
- Sponsor
- Helsinki University Central Hospital
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
Cardiac Structure and Function in Patients with Cystic Fibrosis
In a prospective observational cohort study (n = 100), the investigators aim to assess the correlation between cardiac biomarkers, advanced echocardiography and cystic fibrosis genotype and severity and determine whether these…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis, Pulmonary, Cystic Fibrosis of Pancreas
- Trial name
- NCT06084468
- Where
- 2 sites in Denmark
- Volunteers
- 104 people
- Sponsor
- Herlev and Gentofte Hospital
Kidney Transplant; Complications, Pancreas Disease
Study of OmniGraft in Simultaneous Pancreas Kidney Recipients
The purpose of this research is learn about how OmniGraf works in kidney pancreas transplant patients. Also, to analyze the performance characteristics of OmniGrafTM (TruGraf Gene Expression Profiling (GEP) and T Cell Receptor…
- Trial name
- NCT06463873
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Cancer, Cancer Metastatic
The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
The purpose of this prospective, interventional, single-arm pilot study is to evaluate whether virtually delivered group-based physical activity is feasible for adolescent and young adult (AYA) cancer survivors.
- Conditions
- Cancer, Cancer Metastatic, Neoplasms, Breast Cancer
- Trial name
- NCT05131815
- Testing
- Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pancreas; Fistula, Pancreas Cancer
Assessing Pancreatic Fistula Rates After Distal Pancreatectomy Using AEON Endostapler
This prospective, observational study evaluates the rate of postoperative pancreatic fistula (POPF) following distal pancreatectomy (DP) using the AEON™ Endostapler.
- Conditions
- Pancreas; Fistula, Pancreas Cancer, Pancreatic Disease, Surgery-Complications
- Trial name
- AEON-DP (NCT06764134)
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- University Hospital Heidelberg
Adenocarcinoma, Adenocystic Carcinoma
The Registry of Oncology Outcomes Associated With Testing and Treatment
This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation.
- Conditions
- Adenocarcinoma, Adenocystic Carcinoma, Anal Cancer, Appendix Cancer
- Trial name
- ROOT (NCT04028479)
- Testing
- Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Taproot Health
Pancreas Disease
Virtual Mind-Body Exercises for People Having Pancreatic Surgery
The purpose of this study is to find out if it is practical to provide 2 interventions, VMB exercise classes and EUC (pre-recorded self-care videos), during the perioperative period (before and after surgery) to improve…
- Trial name
- NCT05431556
- Testing
- Virtual mind-body group exercise classes, Enhanced usual care
- Where
- 7 sites in United States
- Volunteers
- 29 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neuroendocrine Neoplasm, Neuroendocrine Neoplasm of Gastrointestinal Tract
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
Neuroendocrine neoplasms (NENs) are a heterogeneous group of lesions derived from cells with the ability to produce hormones that may arise from multiple different organs.
- Conditions
- Neuroendocrine Neoplasm, Neuroendocrine Neoplasm of Gastrointestinal Tract, Neuroendocrine Neoplasm of Lung, Thymic Neuroendocrine Neoplasm
- Trial name
- NCT06523582
- Where
- 3 sites in Mexico
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Ultrasound, Thyroid
Clinical Trial to Evaluate the Effectiveness and Safety of a Remote Automated Ultrasound Diagnostic System for Automated Ultrasound Examinations: a Prospective, Multicenter Study
The purpose of this clinical trial is to verify the safety and effectiveness of the remote automatic ultrasound diagnosis system produced by Wuhan Cooper Technology Co., Ltd. for automatic ultrasound examination.
- Conditions
- Ultrasound, Thyroid, Carotid Artery, Liver
- Trial name
- NCT06487312
- Testing
- Test equipment: Name: Remote automatic ultrasound diagnostic system (Wuhan Cooper Technology Co., Ltd.) Model: CORUS-A30
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Neuroendocrine Tumors, Progression
Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors
Everolimus is approved in many countries to treat patients with advanced/metastatic well-differentiated neuroendocrine tumors (NET), providing median progression-free survival times of approximately 12 months across different…
- Conditions
- Neuroendocrine Tumors, Progression, Neuroendocrine Tumor Grade 1, Neuroendocrine Tumor Grade 2
- Trial name
- EVENET (NCT06472388)
- Testing
- Everolimus 5 MG
- Where
- 2 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- AC Camargo Cancer Center
Pancreas Disease
Total Pancreatectomies in Germany - Epidemiology, Trends,
The purpose of this study was to evaluate the real-world mortality rates of total pancreatectomy across Germany and to understand the impact of hospital caseload on surgical outcomes.
- Trial name
- ToPaGe (NCT06466928)
- Testing
- Total pancreatectomy
- Volunteers
- 12,938 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Liver Diseases, Pancreas Disease
Enhanced Recovery After Surgery for Hepatobiliary-Pancreatic Surgery
ERAS protocols have been utilized extensively in abdominal and non abdominal surgery over the past 20 years. These protocols incorporate evidence based, multi-disciplinary peri-operative care components.
- Trial name
- NCT03772392
- Testing
- HPB resection
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Edinburgh
Pancreas Disease
Role of Patient Selection for Pancreatic Resections
Pancreatic surgery is complicated and risky, especially for pancreatic cancer. It's been noticed that having these surgeries done at specialized centers can lead to better outcomes and survival rates.
- Trial name
- PatSelPanc (NCT06390891)
- Testing
- Persons with pancreatic resection in a hospital with at least 50 pancreatic resections annually (observational),, Persons with pancreatic resection in a hospital not performing at least 50 pancreatic resections annually (observational),
- Volunteers
- 86,073 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Pancreas Disease, Liver Diseases
Motorized Fine Needle Biopsy vs Standard Needles
Recent improvements in punctures techniques and needles now allow for the collection of high-quality specimens comparable to core needle biopsy.
- Trial name
- NCT06298604
- Testing
- EUS-guided standard fine needle biopsy, EUS-guided motorized fine needle biopsy
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreas Cancer, Diagnosis
Diagnosis of Pancreatic Cancer by Purine Metabolite (Hypoxanthine, Xanthine) in Urine
This study aim to develope a diagnostic method of pancreatic cancer by using a reagent for analyzing purine metabolite (Hypoxanthine, Xanthine) in urine. It is safe and cost effective compare to radiologic or blood test.
- Trial name
- NCT06291779
- Testing
- Purine metabolite (Hypoxanthine, Xanthine) in urine by CubeBio
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ho-Seong Han