Clinical trials: Pancreas Diseases
Emergencies, Pancreas Disease
Emergency Pancreaticoduodenectomy: a Non-trauma Center Case Series
Pancreaticoduodenectomy is a challenging procedure itself, being even more complex and demanding in emergency settings. Only a few cases of emergency pancreaticoduodenectomy (EPD) are reported in medical literature, usually…
- Trial name
- NCT05139394
- Testing
- emergency pancreaticoduodenectomy
- Volunteers
- 4 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pancreas Cancer, Pancreas Disease
Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy
Despite improvements and advances in pancreas surgery, about 30-35% of patients who have pancreas surgery develop a type of complication called a pancreatic fistula.
- Conditions
- Pancreas Cancer, Pancreas Disease, Pancreas Adenocarcinoma, Pancreas; Fistula
- Trial name
- PATCH-DP (NCT03410914)
- Testing
- Hemopatch
- Where
- 7 sites in Canada
- Volunteers
- 52 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cystic Fibrosis, Cystic Fibrosis Gastrointestinal Disease
Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEs
This is a Phase 2 study sponsored by AzurRx SAS and involves testing of a new medication for the compensation of exocrine pancreatic insufficiency (EPI) caused by cystic fibrosis (CF).
- Conditions
- Cystic Fibrosis, Cystic Fibrosis Gastrointestinal Disease, Cystic Fibrosis of Pancreas
- Trial name
- NCT04302662
- Testing
- MS1819-SD
- Where
- 10 sites in Hungary, Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- AzurRx SAS
Pancreas Disease, Fistula Pancreatic
Prevention of CR-POPF in PD With the Technique of Connexion the Pancreatic Duct to Jejunum Stented (CONDUCTJE-ST).
Objective: To assess the efficacy of the "connexion pancreatic duct to jejunum stented (CONDUCTJE-ST)" technique to prevent clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreaticoduodenectomy (PD).
- Trial name
- CONDUCTJE-ST (NCT04898517)
- Testing
- Pancreaticoduodenectomy with the CONDUCTJE-ST technique
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Surgery--Complications, Pancreas Disease
Prospective Snapshot Audit of Distal Pancreatectomy in Spain
Distal pancreatectomy is the surgical technique performed to treat many pancreatic diseases located in neck and tail of the pancreas.
- Conditions
- Surgery--Complications, Pancreas Disease, Pancreatic Fistula
- Trial name
- Spadispan (NCT04900012)
- Testing
- Distal pancreatectomy
- Volunteers
- 500 people
- Sponsor
- Hospital General Universitario de Alicante
Bile Duct Disorder, Endocrine Pancreas Disorder
Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Pancreas and Bile Duct Disorders
This trial determines the feasibility of Laryngeal Mask Airway Gastro (Laryngeal Mask Airway) when used on patients who are undergoing endoscopic retrograde cholangiopancreatography for pancreas and bile duct disorders.
- Trial name
- NCT03775681
- Testing
- Endoscopic Retrograde Cholangiopancreatography, Interview, Laryngeal Mask Airway
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Liver Diseases, Pancreas Disease
Diagnostic and Evaluation of Hepato-pancreatico-biliary Disease With MRI
This is a retrospective review of images from patient data. There is no recruitment necessary for this study. Research Question: Can advanced multiparametric MRI techniques improve the detection and characterization of focal and…
- Trial name
- NCT04701567
- Testing
- Magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University of Zurich
Pancreas Disease, Liver Diseases
Results of Surgical Treatment of the Hepatobiliopancreatic Surgical Unit
The main aims of this study are: 1. - to evaluate post-surgical morbidity and mortality outcomes, following the criteria and the definitions from Claven-Dindo and ISGPS international classifications, of the patients operated by…
- Conditions
- Pancreas Disease, Liver Diseases, Surgical Procedure, Unspecified, Bile Duct Diseases
- Trial name
- HPB (NCT04556019)
- Testing
- Hepatobiliopancreatic surgery
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacion Miguel Servet
Biliary Stricture, Pancreas Cancer
Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study
The purpose of this study is to assess the interobserver agreement (IOV) for pancreatico-biliary Volumetric Laser Endomicroscopy (VLE) de-identified clips using the new VLE criteria.
- Conditions
- Biliary Stricture, Pancreas Cancer, Cholangiocarcinoma, Bile Duct Cancer
- Trial name
- VLE-IOV (NCT03951324)
- Testing
- Interobserver agreement or Interrater agreement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Innovative Digestive Health Education and Research Inc
Adenocarcinoma of the Pancreas, Metastatic Disease
Study of AUY922 in Metastatic Pancreatic Cancer Who Are Resistant to First Line Chemotherapy
This is a phase II study to see how useful study drug AUY922 is in patients with metastatic pancreatic cancer who have received or are intolerant to first-line chemotherapy.
- Trial name
- NCT01484860
- Testing
- AUY922
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Tumors of the Pancreas, Submucosal Tumor of Gastrointestinal Tract (Disorder)
Prospective Evaluation of the Diagnostic Efficacy of a EUS Guided FNB Needle (AQUIRE®)
The present study investigates the efficacy of a new Endoultrasound guided fine needle biopsy (EUS-FNB) device (AquireTM Boston Scientific= AQUIRE®) for obtaining histological tissue cylinders in the diagnosis of solid pancreatic…
- Conditions
- Tumors of the Pancreas, Submucosal Tumor of Gastrointestinal Tract (Disorder), Lymph Node Disease
- Trial name
- NCT03621852
- Testing
- Endoultrasound guided FNB
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Philipps University Marburg
Colorectal Cancer With Hepatic Metastases, Pancreas Cancer With Hepatic Metastase
TKM 080301 for Primary or Secondary Liver Cancer
Background: Cancer in the liver can start in the liver (e.g., primary liver cancer or hepatocellular cancer) or spread to the liver from cancers in other parts of the body (e.g.
- Conditions
- Colorectal Cancer With Hepatic Metastases, Pancreas Cancer With Hepatic Metastase, Gastric Cancer With Hepatic Metastase, Breast Cancer With Hepatic Metastase
- Trial name
- NCT01437007
- Testing
- TKM-080301
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Biliary Disease, Pancreas Disease
Laparoscopy-assisted ERCP in Patients With Altered Gastric Anatome
The purpose of this research study is to collect data on the technical aspects of Lasparoscopy-assisted ERCP and patient outcomes to help guide future medical care of patients with Roux-en-Y gastric bypass surgery.
- Trial name
- NCT01620632
- Testing
- Laparoscopy assisted ERCP
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
CKD (Chronic Kidney Disease) Stage 5T, Diabetes Mellitus
Observational Study to Evaluate the Safety and Efficacy of Polyclonal Antibodies in Simultaneous Pancreas Kidney Transplant Recipients
A single-centre, prospective, observational study to evaluate the safety and efficacy of Polyclonal Antibodies in simultaneous Pancreas Kidney Transplant recipients.
- Conditions
- CKD (Chronic Kidney Disease) Stage 5T, Diabetes Mellitus, Simultaneous Pancreas Kidney Transplantation
- Trial name
- PAISPK (NCT03470961)
- Testing
- Anti-Tlymphocyte Globulins, Anti-Thymocyte Globulins
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Tianjin First Central Hospital
Non-Alcoholic Fatty Pancreas Disease, Acute Pancreatitis
The Impact of Non-Alcoholic Fatty Pancreas Disease on Outcome of Acute Pancreatitis
Obesity is a well-established risk factor for acute pancreatitis (AP). As for non-alcoholic fatty pancreas disease (NAFPD), it is evident that it is correlated with obesity.
- Trial name
- NCT03394378
- Where
- China
- Volunteers
- 1,662 people
- Sponsor
- Ningbo No. 1 Hospital
Cystic Fibrosis, Cystic Fibrosis Liver Disease
Utility of Point Shear-wave Elastography to Assess for Hepatic & Pancreatic Fibrosis in Pediatric CF Patients
Diagnosis of hepatic fibrosis is challenging as specific tests for detection of fibrosis in pediatric Cystic Fibrosis associated liver disease (CFALD) have not been developed and existing investigations do not correlate well with…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis Liver Disease, Pancreatic Insufficiency Due to Cystic Fibrosis of Pancreas
- Trial name
- CFALD (NCT03264950)
- Testing
- Elastography
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Lesion; Gastrointestinal, Liver, Biliary, Pancreas and Gastrointestinal Disease, Nos
CO2 vs. Air Insufflation for Endoscopic Ultrasound
The insufflation of air in the viscera is indispensable during endoscopy. However, the distension of the bowel that follows is often the cause of abdominal discomfort.
- Trial name
- NCT02773563
- Testing
- EUS with air insufflation, EUS with CO2 insufflation
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Bologna
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Kidney Disease, Liver Disease
Remote Ischemic Preconditioning In Abdominal Organ Transplantation
Does remote ischemic preconditioning (RIPC) induced by a brief period of occlusion of blood flow to the lower extremity prior to organ recovery in deceased donors, improve short and long term outcomes after transplantation of…
- Conditions
- Kidney Disease, Liver Disease, Pancreas Disease
- Trial name
- RIPCOT (NCT00975702)
- Testing
- RIPC by Inflation of Pneumatic Tourniquet
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Inflammatory Bowel Disease, Hepatobiliary Disease
Risk of Methicillin-resistant S.Aureus (MRSA) Infections in MRSA Carrier Under Introduction of Rapid MRSA Screening
This study was designed to evaluate the effect of a targeted preoperative Methicillin-resistant Staphylococcus aureus (MRSA) detection by polymerase chain reaction (PCR) on either endogenous or exogenous postoperative MRSA…
- Conditions
- Inflammatory Bowel Disease, Hepatobiliary Disease, Pancreas Disease
- Trial name
- NCT01918813
- Testing
- vancomycin, mupirocin ointment
- Where
- Japan
- Volunteers
- 662 people
- Sponsor
- Chikara Tashiro