Clinical trials: Pancreas Neoplasm, Benign
Pancreas Cancer
DNA Microarray Study of Pancreas Cancer
Pancreas cancer and precancerous cysts can be difficult to diagnose. Sometimes biopsies do not show cancer when cancer is actually present.
- Trial name
- NCT00680420
- Testing
- fine needle aspiration biopsy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Oregon Health and Science University
Minimally Invasive Distal Pancreatectomy
Registrar Performances in MIDP
This study aimed to determine whether registrar involvement in minimally invasive distal pancreatectomy (MIDP) was associated with adverse outcomes.
- Trial name
- NCT04429074
- Testing
- Minimally invasive distal pancreatectomy
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Cancer, Breast Neoplasm
Development of Assist Tool for Breast Examination Using the Principle of Ultrasonic Sensor
The accuracy of breast examinations and ultrasonography performed clinically to detect breast mass varies greatly depending on the physician\'s skill level, and the accuracy of breast examinations by non-experts is…
- Conditions
- Breast Cancer, Breast Neoplasm, Artificial Intelligence, Ultrasonography
- Trial name
- NCT06255808
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Benign Pancreatic Neoplasm, Chronic Pancreatitis
A Surgical Procedure (Total Pancreatectomy) With a Transplant Procedure (Islet Cell Autotransplantation) for the Treatment of Chronic Pancreatitis and Benign Pancreatic Tumors
This phase I/II trial assesses the safety and effectiveness of total pancreatectomy with islet cell autotransplantation for the treatment of patients with long-term pancreatic inflammation (chronic pancreatitis) and non-cancerous…
- Conditions
- Benign Pancreatic Neoplasm, Chronic Pancreatitis, Recurrent Acute Pancreatitis
- Trial name
- NCT05453851
- Testing
- Pancreatectomy, Quality-of-Life Assessment, Treatment Planning
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- OHSU Knight Cancer Institute
Microbiome, Pancreatic Neoplasms
Fecal and Oral Microbiota Between Pancreatic Cancer and Benign/Low-grade Malignant Tumor Patients
Significant gaps exist in understanding the gastrointestinal microbiota in patients with pancreatic cancer (PCA) versus benign or low-grade malignant pancreatic tumors (NPCA).
- Conditions
- Microbiome, Pancreatic Neoplasms, 16s RRNA
- Trial name
- NCT06659237
- Testing
- 16s rRNA or shotgun metagenomics
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Women At Risk: The High Risk Breast Cancer Program
The purpose of this study is to increase understanding of women who are at high risk for developing breast cancer. Data from this group will be collected and entered into a registry.
- Trial name
- WAR (NCT01034891)
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- New York Presbyterian Hospital
Benign Breast Disease, Breast Cancer
Prolactin Receptor and Breast Diseases
Prolactin is known to play an important role in breast development and differentiation. Thus proliferative breast diseases are good models to unravel PRl / PRLR function in proliferative processes.
- Trial name
- Prolacsein (NCT00842465)
- Testing
- blood collection for hormonal status analysis, breast Biopsy or surgery, blood collection
- Where
- France
- Volunteers
- 735 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fibroadenoma, Breast Fibroadenoma
Management of Breast Fibroadenoma: Comparing Observation, Microwave Ablation, and Surgical Excision
The purpose of this study is to evaluate and compare three different management strategies for benign breast fibroadenoma: conservative management with clinical and radiological follow-up (observation), ultrasound-guided…
- Conditions
- Fibroadenoma, Breast Fibroadenoma, Benign Breast Disease
- Trial name
- NCT07890766
- Testing
- Ultrasound-guided percutaneous microwave ablation, Conventional open surgical excision
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Cholecystitis, Perforated Duodenal Ulcer
Incentive Spirometry and Upper Abdominal Laparoscopic Surgery
To compare the effects of volume-oriented versus flow-oriented incentive spirometry on pulmonary function tests and functional capacity in patients of upper abdominal laparoscopic surgery.
- Conditions
- Cholecystitis, Perforated Duodenal Ulcer, Diaphragmatic Hernia, Benign Pancreas Tumor
- Trial name
- NCT04716166
- Testing
- Volume-oriented incentive spirometry, Flow-oriented incentive spirometry
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Breast Cancer
Comparison of MRI and Molecular Breast Imaging in Breast Diagnostic Evaluation
The purpose of this study is to determine the sensitivity of Molecular Breast Imaging (MBI) relative to MRI of the breast in patients undergoing MRI for a clinical concern, or abnormal diagnostic mammogram and/or ultrasound study.
- Trial name
- MBI (NCT00591864)
- Testing
- Molecular Breast Imaging
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Mayo Clinic
Pancreatic Tumor, Benign, Pancreatic Cancer, Adult
Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer
This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer.
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Cancer, Adult, Pancreatic Cancer Resectable
- Trial name
- MIND-PANC (NCT07529626)
- Where
- 3 sites in China
- Volunteers
- 320 people
- Sponsor
- Shanghai Zhongshan Hospital
Pancreas Cancer, Pancreas Neoplasm, Benign
Endoscopic Ultrasound Guided Tissue Sampling (The SharkBITE Study)
This study compares the diagnostic performance of Endoscopic ultrasound (EUS) guided fine needle aspiration and EUS guided core biopsy (SharkCore) in patients with a solid pancreatic mass.
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Benign, Chronic Pancreatitis, Pancreas Adenocarcinoma
- Trial name
- SharkBITE (NCT03532347)
- Testing
- EUS-FNA needle (Beacon)
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Esophageal Cancer, Bile Duct Neoplasms
Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract
Doctors at Memorial Sloan Kettering Cancer Center and at other institutions study normal and cancer cells. To study these cells we need to have human tissue, body fluids, and blood.
- Conditions
- Esophageal Cancer, Bile Duct Neoplasms, Gastric Cancer, Liver Cancer
- Trial name
- NCT00582647
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Shwachman-Diamond Syndrome, SDS
Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform
The Shwachman-Diamond Syndrome Global Patient Survey and Collaboration Program (SDS-GPS) is an opportunity for patients and their families - from anywhere in the world - to share their experience living with SDS via a safe…
- Conditions
- Shwachman-Diamond Syndrome, SDS, IBMF, Congenital Neutropenia
- Trial name
- SDS-GPS (NCT06999954)
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- Shwachman-Diamond Syndrome Alliance Inc
Pancreas Neoplasm, Pancreas Cancer
Incidence of POPF in the Resection of the Left Pancreas With RFAT
This study evaluates the impact of the Radiofrequency assisted transection on the rate of postoperative pancreatic fistula (POPF) after performing distal pancreatectomies, central pancreatectomies and pancreatic enucleation
- Conditions
- Pancreas Neoplasm, Pancreas Cancer, Pancreatic Adenocarcinoma, Benign Pancreas Tumor
- Trial name
- RFATPancreas (NCT03570502)
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Hospital del Mar
Benign Neoplasm of Liver and/or Biliary Ducts, Neoplasm of Uncertain Behavior of Biliary System
Endoscopic Evaluation of Premalignant Lesions in the Biliary Tract and Pancreatic Ducts
Single operater pancreatico-cholangioscopy is performed through the working channel of conventional duodenoscopes. A visual evaluation of the biliary and pancreatic ductal systems is completed and obvious or suspicious…
- Conditions
- Benign Neoplasm of Liver and/or Biliary Ducts, Neoplasm of Uncertain Behavior of Biliary System, Benign Neoplasms of the Pancreas, Neoplasms of the Pancreas
- Trial name
- NCT02057146
- Testing
- Duodenoscopy, pancreatoscopy, cholangioscopy, confocal microscopy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska University Hospital
Partial Pancreatectomy Due to Benign Pancreatic Neoplasm
Effect of Islet Autotransplantation Compared to Oral Antidiabetic Drug.
Effects of autologous islet transplantation were compared to those of oral anti-diabetic drugs after distal pancreatectomy. The primary interest is a insulin-secretory function after the surgery in two intervention groups.
- Trial name
- NCT01922492
- Testing
- Autologous islet transplantation, Oral anti-diabetic drugs
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Seoul National University Hospital
Pancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor
Pancreatic Fistula After Minimally Invasive Enucleation
Patients suffering from postoperative pancreatic fistula (POPF) after minimally invasive enucleation (MIEN) show a characteristic pattern of longer duration and milder symptoms, which is different from pancreatic fistula after…
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor, Solid Pseudopapillary Tumor of the Pancreas
- Trial name
- NCT06557408
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Fudan University
Pancreatic Tumor, Benign, Solid Pseudopapillary Tumor of the Pancreas
Oncologic Safety and Lymphadenectomy in Parenchyma-Sparing Resection for SPN
Solid pseudopapillary neoplasm (SPN) of the pancreas is a low-grade malignant tumor primarily treated with surgical resection. However, the oncologic safety of parenchyma-sparing resection (PSR) and the necessity of…
- Trial name
- PSR for SPN (NCT07592663)
- Testing
- Parenchyma-sparing resection
- Where
- China
- Volunteers
- 708 people
- Sponsor
- Fudan University