Clinical trials: Pancreas Tumor
Carcinoma, Pancreatic Ductal
Efficacy Study of Gemcitabine, Paclitaxel, and Irradiation in the Treatment of Pancreatic Cancer
The purpose of this study is to find out what effects, good and bad, the chemotherapy drugs gemcitabine (Gemzar) and paclitaxel (Taxol) have in combination with twice daily radiation treatment on locally advanced pancreatic…
- Trial name
- NCT00226746
- Testing
- Paclitaxel and gemcitabine
- Where
- United States
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Pancreatic Adenocarcinoma
Trial of Gemcitabine With or Without MSC1936369B in Pancreatic Cancer
The research trial is testing the experimental treatment MSC1936369B in combination with Gemcitabine, in subjects with metastatic pancreatic adenocarcinoma.
- Trial name
- NCT01016483
- Testing
- Pimasertib, Gemcitabine
- Where
- 2 sites in United States, Germany
- Volunteers
- 141 people
- Sponsor
- EMD Serono
Minimal Residual Disease, KRAS G12D
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors
This is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide [Amph-CpG-7909] plus a mixture of lipid-conjugated peptide-based antigens [Amph-Peptides])…
- Conditions
- Minimal Residual Disease, KRAS G12D, KRAS G12R, NRAS G12D
- Trial name
- AMPLIFY-201 (NCT04853017)
- Testing
- ELI-002 2P
- Where
- 10 sites in United States
- Volunteers
- 25 people
- Sponsor
- Elicio Therapeutics
Pancreatic Neoplasms
Comparation Between Needles for EUS-guided Sampling of Solid Pancreatic Lesions
This is a randomized study in order to compare the diagnostic yield (primary outcome) of EUS-guided sampling of pancreatic solid lesions obtained with the 25-gauge Franseen and the 25-gauge standard needle in patients undergoing…
- Trial name
- NCT04877340
- Testing
- needle punction
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Metastatic Pancreatic Cancer
A Multi-center, Single-arm, Prospective Non-interventional Study to Investigate the Safety Profiles and Effectiveness of Liposomal Irinotecan (ONIVYDE®) in Combination with 5-fluorouracil (5-FU) and Leucovorin (LV) in Chinese Patients with Metastatic Pancreatic Cancer As Approval Condition (SEOPAC)
The aim of this phase 4 study is to evaluate the safety profile of ONIVYDE in China mainland. Primary objective To characterize the safety of ONIVYDE when used under standard clinical practice in China mainland on the following…
- Trial name
- SEOPAC (NCT06688240)
- Volunteers
- 120 people
- Sponsor
- Servier (Tianjin) Pharmaceutical Co. LTD.
Endoscopic Ultrasonography, EUS-FNA
Heparin-based Wet Suction Method in EUS Fine Needle Biopsy of Solid Pancreatic Mass
The objective of this randomized cross-over trial is to evaluate whether Heparin based wet suction technique, compared with dry suction technique, shall present a higher quality tissue core by using quantitative macroscopic and…
- Conditions
- Endoscopic Ultrasonography, EUS-FNA, Pancreatic Neoplasms
- Trial name
- NCT04707560
- Testing
- EUS fine needle biopsy with heparin wet suction
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng-Kung University Hospital
Intraductal Papillary Mucinous Neoplasm of Pancreas
Feasibility Trial of EUS-PCA in IPMN Pancreatic Cysts
The goal of this single-arm intervention trial is to determine the feasibility of implementing endoscopic ultrasound-guided pancreatic cyst chemoablation (EUS-PCA) using gemcitabine and paclitaxel for intraductal papillary…
- Trial name
- NCT06162468
- Testing
- Endoscopic ultrasound-guided pancreatic cyst chemoablation (EUS-PCA) using gemcitabine and paclitaxel
- Where
- 2 sites in New Zealand
- Volunteers
- 20 people
- Sponsor
- University of Auckland, New Zealand
Pancreatic Neoplasms, Rectal Neoplasms
Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer
This study will evaluate light therapy used in combination with standard therapies for pancreatic and rectal cancer. Participants will receive chemotherapy, radiation, and surgical treatments identical to that they had not been…
- Trial name
- NCT06164691
- Testing
- Blue light, Amber light, Ambient White Light
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Matthew Neal MD
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Oxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metastatic Pancreatic Cancer or Biliary Tract Cancer
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Pancreatic Cancer
- Trial name
- NCT00266097
- Testing
- erlotinib hydrochloride, gemcitabine hydrochloride, oxaliplatin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
HER2 Positive Gastric Cancer, Colorectal Cancer
FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors
This is a Phase 1, single-dose, open-label, dose-escalation study. The study will be conducted in three parts (i.e. regimens) in an outpatient setting as follows: Regimen A: FATE-NK100 as a monotherapy in subjects with advanced…
- Conditions
- HER2 Positive Gastric Cancer, Colorectal Cancer, Head and Neck Squamous Cell Carcinoma, EGFR Positive Solid Tumor
- Trial name
- NCT03319459
- Testing
- FATE-NK100, Cetuximab, Trastuzumab
- Where
- 4 sites in United States
- Volunteers
- 44 people
- Sponsor
- Fate Therapeutics
Colon Neoplasm, Colon Adenocarcinoma
Peptide-based Immunization for Colon- and and Pancreas-carcinoma
An international, multicenter study to identify tumor molecular particularities and neoepitopes among participants with colorectal and pancreatic tumors undergoing surgery.
- Conditions
- Colon Neoplasm, Colon Adenocarcinoma, Colon Cancer, Colo-rectal Cancer
- Trial name
- PICOP-GLOBAL (NCT03871790)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- CENTOGENE GmbH Rostock
Pancreatic Neuroendocrine Neoplasm
Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
This is a prospective observational multi-center pilot study of germline testing for participants receiving care at University of California participating locations with a new or existing diagnosis of Pancreatic Neuroendocrine…
- Trial name
- PanNEN (NCT05746182)
- Testing
- Hereditary Cancer Panel
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco
Pancreatic Cancer
Nab-paclitaxel Plus S-1(AS) Versus Nab-paclitaxel Plus Gemcitabine(AG) in Patients With Advanced Pancreatic Cancer
This is a randomized phase II trial comparing the first-line treatment with nab-paclitaxel plus S-1(AS) and nab-paclitaxel plus gemcitabine(AG) in advanced pancreatic ductal adenocarcinoma (PDA) with primary tumor nonexcision in…
- Trial name
- ASAGPAC (NCT03636308)
- Testing
- nanoparticle albumin-bound paclitaxel, S1, Gemcitabine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University
Pancreatic Neoplasm
Delayed Gastric Emptying After Pancreatic Surgery
Delayed gastric emptying (DGE) is a common complication of pancreatic surgery. Once it occurs, it often affects the patient's postoperative quality of life and may even delay subsequent necessary treatments, such as adjuvant…
- Trial name
- NCT07382791
- Testing
- pancreatectomy
- Where
- Taiwan
- Volunteers
- 3,500 people
- Sponsor
- National Taiwan University Hospital
Pancreatic Cancer, Neoadjuvant Therapy
Robotic Versus Open Surgery Following Neoadjuvant Therapy in Pancreatic Cancer: Evaluation of Safety and Oncologic Outcomes
The feasibility and safety of minimally invasive surgery in cases after neoadjuvant therapy were unclear. It is worth exploring the safety of robotic resection for pancreatic cancer following neoadjuvant therapy.
- Conditions
- Pancreatic Cancer, Neoadjuvant Therapy, Robotic Surgery
- Trial name
- NCT07147374
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Neoplasms
Tamoxifen for Advanced Solid Pseudopapillary Tumor of the Pancreas
Tamoxifen for Solid Pseudopapillary Tumor of the Pancreas
- Trial name
- SPTP (NCT06914674)
- Testing
- Tamoxifen 20 mg
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fudan University
Exocrine Pancreatic Cancer
PATAKESS Protocol : Clinical and Biological Analysis of Exocrine Pancreatic Tumors
PATAKESS is a monocentric non interventional cohort study (prospective (alive patients) and retrospective (dead patients with biological material from surgery and/or biopsies already collected)).
- Trial name
- PATAKESS (NCT04011982)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Leon Berard
Abdominal Cancer
Tidal Volume Challenge and Reliability of Plethysmography Variability Index
The aim of this study is to investigate whether a temporary increase in tidal volume can predict fluid responsiveness in patients receiving a low tidal volume ventilation in hepatobiliary and pancreatic surgeries.
- Trial name
- NCT03546179
- Testing
- tidal volume challenge test, Volume loading
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Fayoum University Hospital
Pancreatic Neoplasms, Inflammation
Dynamic Changes of Sera Immunoglobulin G4 and Interleukin-10 in the Patients of Pancreatic Cancer After Chemotherapy
Investigators have previously found that the infiltration of immunoglobulin G4(IgG4) positive plasma cells in tumor tissue predicts a poor prognosis of pancreatic cancer after curative resection.
- Trial name
- NCT02654288
- Testing
- gemcitabine-based chemotherapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Pseudocyst Pancreas, Pancreatic Duct Disorder
The Economic Impact of the Pancreatography in the Endoscopic Treatment of Pancreatic Pseudocysts
Pancreatic pseudocysts (PP) present as a complication that occurs in 5-15% of acute pancreatitis and 26-40% of chronic pancreatitis (1-3).
- Trial name
- NCT04494282
- Testing
- Endoscopic retrograde pancreatography
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.