Clinical trials: Pancreatic Disorders
Bupivacaine, Ultrasound-Guided
Bupivacaine Liposomes or Bupivacaine for CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery
Numerous studies have confirmed that regional analgesia using peripheral nerve block has great potential for perioperative analgesia in abdominal surgery.
- Conditions
- Bupivacaine, Ultrasound-Guided, Analgesia, Postoperative, Opioids
- Trial name
- NCT06737341
- Testing
- Bupivacaine Liposomes(BL), Bupivacaine(B)
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Pancreatic Cancer Stage III, Pancreatic Cancer Stage IV
The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
Aberrant miRNA production has been linked to a wide range of human cancers and shown to play important roles in their genesis and growth. These miRNA can be detected in the blood and tumors of patients with cancer.
- Conditions
- Pancreatic Cancer Stage III, Pancreatic Cancer Stage IV, Pancreatic Ductal Adenocarcinoma, Pancreatic Neoplasms
- Trial name
- NCT04406831
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nuvance Health
Pancreatic Cancer
Celecoxib, Irinotecan and Concurrent Radiotherapy in Preoperative Pancreatic Cancer
The purposes of this study are to examine the effects of a new combination of drugs, celecoxib (Celebrex®) and irinotecan (CPT-11), with standard radiation therapy on people before they undergo surgery; to determine what effects…
- Trial name
- NCT00177853
- Testing
- celecoxib, irinotecan, concurrent radiotherapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pittsburgh
Carcinoma, Pancreatic Ductal, Colorectal Neoplasms
A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.
The purpose of this study is to learn about the safety and effects of the study medicine alone or when given together with other anti-cancer therapies. This study also aims to find the best dose.
- Conditions
- Carcinoma, Pancreatic Ductal, Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT06447662
- Testing
- PF-07934040, Gemcitabine, Nab-paclitaxel
- Where
- 27 sites in United States, Puerto Rico
- Volunteers
- 64 people
- Sponsor
- Pfizer
Diabetes
Nitrite Infusion in Islet Cell Transplantation
This study seeks to investigate the effects of administering nitrite to pancreatic islet cells that have been removed from a patient for autotransplantation.
- Trial name
- NCT03544242
- Testing
- Control, Pre-Isolation Infusion, Post-Isolation Infusion
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Alabama at Birmingham
Pancreatic Neoplasm
A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients
Radiation therapy improves cancer cure rates by killing cancer cells but it also contributes to long-term side effects in cancer survivors by unintentionally damaging normal organs such as the intestine.
- Trial name
- XACT-PANC-2 (NCT03541486)
- Testing
- Ascorbate, Gemcitabine, radiation therapy
- Where
- United States
- Sponsor
- Joseph J. Cullen, MD, FACS
Lung Cancers, Liver Cancer
AI-Assisted Non-Contrast CT for Multi-Cancer Screening
Cancer poses a major public health challenge in China. Early detection can improve treatment outcomes and survival rates. In this study, we will conduct a large-scale, prospective, multi-center cohort study to evaluate the…
- Conditions
- Lung Cancers, Liver Cancer, Gastric Cancers, Colorectal, Cancer
- Trial name
- NCT06632886
- Testing
- AI-Assisted Non-Contrast CT for Multi-Cancer Screening
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Guo ShiWei
Pancreatitis, Chronic Pancreatitis
Varenicline for Smoking Cessation in Pancreatitis
This study will look at how safe and how effective varenicline, a commonly used medication for smoking cessation, is in helping patients with pancreatitis stop smoking cigarettes.
- Conditions
- Pancreatitis, Chronic Pancreatitis, Acute Pancreatitis (AP), Recurrent Acute Pancreatitis
- Trial name
- NCT07874841
- Testing
- Varenicline (VAR)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Breast Cancer, Colon Cancer
Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer
This pilot clinical trial studies copper Cu 64 anti-carcinoembryonic antigen (CEA) monoclonal antibody M5A positron emission tomography (PET) in diagnosing patients with CEA positive cancer.
- Conditions
- Breast Cancer, Colon Cancer, Extrahepatic Bile Duct Cancer, Gallbladder Cancer
- Trial name
- NCT02293954
- Testing
- radionuclide imaging, positron emission tomography, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Pancreatic Adenocarcinoma, Colorectal Cancer
Micrometastasis in Gastrointestinal Cancer
Prognostic and predictive value of assessing the patients micrometastasis status in blood and bone marrow when diagnosed GI cancer.
- Trial name
- NCT01919151
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Metastatic Pancreatic Cancer, Metastatic Biliary Tract Cancer
Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patients
This is a prospective, randomized, open-label phase 2 study in patients with metastatic PC or BTC refractory or intolerant to at least one line of prior systemic chemotherapy with gemcitabine or platinum-containing regimens to…
- Trial name
- CheckPAC (NCT02866383)
- Testing
- Nivolumab, Ipilimumab, Radiotherapy
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Herlev Hospital
Pancreatic Neoplasms
EUS Fiducial for Pancreas Surgery
RATIONALE: Pancreas tumor localization makes minimally invasive surgical resection of pancreas tumors very challenging. Recently, an endoscopic ultrasound needle system has been developed which enables fiducial coils to be placed…
- Trial name
- NCT02863783
- Testing
- EUS with Fiducial
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Pancreatic Neoplasms
Clinical Efficacy of QYHJ and Standard Chemotherapy in the Treatment of Advanced Pancreatic Cancer
This prospective, multicenter, randomized, double-blind, placebo-controlled phase 3 trial included adults with histologically or cytologically confirmed stage IV pancreatic ductal adenocarcinoma who were eligible for…
- Trial name
- NCT05840341
- Testing
- QingyiHuaji optimized formula
- Where
- 4 sites in China
- Volunteers
- 305 people
- Sponsor
- Fudan University
Cystic Fibrosis
ENHANCE- Establishing Natural History in an Advanced New CF Care Era
Measured outcomes for people with CF have improved dramatically over the last 20 years, even prior to the widespread introduction of cystic fibrosis transmembrane conductance regulator (CTFR) modulator treatments.
- Trial name
- NCT05986045
- Testing
- Quality of Life
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Cystic Fibrosis, Pseudomonas Aeruginosa
Nasal Inhalation of Tobramycin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization
The purpose of this study is to determine whether the nasal inhalation of Gernebcin® is effective to decrease the Pseudomonas aeruginosa bacterial count in the nasal lavage fluid.
- Trial name
- NCT00774072
- Testing
- Tobramycin (Gernebcin®)
- Where
- 2 sites in Germany
- Volunteers
- 9 people
- Sponsor
- University of Jena
Type 1 Diabetes
Closing the Loop in Adults With Type 1 Diabetes Under Free Living Conditions
The main objective of this study is to determine whether home use of day and night closed loop insulin delivery under free living conditions applying faster insulin aspart (FiAsp) is non-inferior to home use of closed-loop…
- Trial name
- AP@Home04_P3 (NCT04055480)
- Testing
- Closed-loop using standard rapid-acting insulin, Closed-loop using faster insulin aspart
- Where
- 4 sites in Austria, Switzerland and 1 more
- Volunteers
- 25 people
- Sponsor
- University of Cambridge
Pancreatic Cancer
Biomarkers in Plasma Specimens From Patients Treated on Study CALGB-80303
RATIONALE: Studying plasma samples from patients with pancreatic cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT01664169
- Testing
- laboratory biomarker analysis
- Volunteers
- 307 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pancreatic Cancer, Pancreatic Adenocarcinoma
MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic Cancer
Objectives: Primary Objectives: Phase I: Determine the maximal tolerated dose (MTD) of MK-0646 in combination with gemcitabine or gemcitabine plus erlotinib and recommended phase II dose.
- Trial name
- NCT00769483
- Testing
- MK-0646, Gemcitabine, Erlotinib
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Cancer, Pancreatic Adenocarcinoma
EUS BD vs ERCP TP for Pancreatic Cancer
This Endoscopic Ultrasound guided Biliary Drainage (EUS-BD) vs. Endoscopic Retrograde Cholangiopancreatography (ERCP-TP) trial (BILPAL) is a randomized controlled multicenter trial that will provide evidence whether or not…
- Conditions
- Pancreatic Cancer, Pancreatic Adenocarcinoma, Biliary Tract Neoplasms, Biliary Duct Obstruction
- Trial name
- BILPAL (NCT03063554)
- Testing
- Endoscopic Ultrasound Guided Biliary Drainage, ERCP
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Weill Medical College of Cornell University
Pancreatic Neoplasms, Pancreatic Cancer
Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer
Background: Stereotactic body radiation therapy (SBRT) is used to treat cancer. It is a way of giving very focused beams of radiation to tumors.
- Conditions
- Pancreatic Neoplasms, Pancreatic Cancer, Cancer of Pancreas, Cancer of the Pancreas
- Trial name
- NCT02311361
- Testing
- Durvalumab, Tremelimumab, Sterostatic body radiation therapy (SBRT)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Cancer Institute (NCI)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.