Clinical trials: Pancreatic Exocrine Insufficiency
Exocrine Pancreatic Insufficiency
BÜHLMANN FPELA in the Diagnosis of Exocrine Pancreatic Insufficiency
The study shall determine the clinical performance of the BÜHLMANN fecal pancreatic elastase (fPELA) assays in the diagnosis of exocrine pancreatic insufficiency (PEI).
- Trial name
- NCT04548778
- Testing
- BÜHLMANN fPELA assay
- Where
- Germany
- Volunteers
- 201 people
- Sponsor
- Bühlmann Laboratories AG
Chronic Pancreatitis, Recurrent Acute Pancreatitis
Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis
This project uses the Malabsorption Blood Test (MBT) to identify patients with recurrent acute or chronic pancreatitis who have mild to moderate exocrine pancreatic insufficiency.
- Conditions
- Chronic Pancreatitis, Recurrent Acute Pancreatitis, Exocrine Pancreatic Insufficiency
- Trial name
- MBT (NCT07418593)
- Testing
- Pancreatic Enzyme Replacement Therapy, MBT1, MBT 2
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Anna Evans Phillips
Chronic Pancreatitis, Pancreatic Exocrine Insufficiency
Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function Tests
The goal of this observational study is to improve the epidemiological data of pancreatic exocrine insufficiency in China, determine the FE-1 cut-off value for the classification of PEI, and explore the characteristic differences…
- Conditions
- Chronic Pancreatitis, Pancreatic Exocrine Insufficiency, Diabetes Mellitus, Community Populations
- Trial name
- NCT06006312
- Testing
- fecal elastase-1 test, 72-hour fecal fat quantification, blood sample test
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Pancreatic Insufficiency
Clinical Non-Inferiority of Pancreatic Enzymes (Norzyme ® - Bergamo) Compared To Creon ® (Solvay Pharmaceutical) in Patients With Exocrine Pancreatic Insufficiency
The primary objective of this clinical trial is to demonstrate non-inferiority clinical development of pancreatic enzymes from Laboratory Bergamo (Norzyme ®) in relation to pancreatic enzymes from Solvay Pharmaceuticals (Creon…
- Trial name
- NCT01012908
- Testing
- Norzyme - Bergamo, Creon
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Azidus Brasil
Cystic Fibrosis Liver Disease, Pancreatic Insufficiency
MRI to Characterize and Predict CF Liver Disease in PUSH Cohort
Specific Aim 1. Determine if valid results of non-sedated MRI based assessments of liver stiffness and lipid content can be obtained in more than 90% of children and young adults with cystic fibrosis. Specific Aim 2.
- Trial name
- NCT02979340
- Testing
- MRI
- Where
- 8 sites in United States
- Volunteers
- 115 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pancreatic Neoplasm, Pancreas Adenocarcinoma
Pancreatic Cancer Dietary Assessment Study
This is a prospective observational study which aims to evaluate; The prevalence of pancreatic insufficiency in patients with pancreatic malignancies (adenocarcinoma and neuroendocrine tumours).
- Conditions
- Pancreatic Neoplasm, Pancreas Adenocarcinoma, Well-Differentiated Neuroendocrine Carcinoma, Malignant Neoplasm of Pancreas
- Trial name
- PanDA (NCT03616431)
- Testing
- Pancreo-KIT breath test
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- The Christie NHS Foundation Trust
Cystic Fibrosis, Pancreatic Exocrine Insufficiency
Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
This study will assess the safety and tolerability of pancrelipase delayed release capsules in subjects up to 6 years of age with Pancreatic Exocrine Insufficiency (PEI) due to Cystic Fibrosis.
- Trial name
- NCT00775528
- Testing
- Pancrelipase Delayed Release
- Where
- 12 sites in United States
- Volunteers
- 19 people
- Sponsor
- Solvay Pharmaceuticals
Chronic Pancreatitis
Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) Symptoms
Exocrine Pancreatic Insufficiency (EPI) is a condition where pancreatic enzyme quantity or activity is reduced below threshold needed for normal digestion. Symptoms include bloating, flatulence, diarrhea and steatorrhea.
- Trial name
- CisCP (NCT04949828)
- Testing
- CREON
- Where
- 6 sites in United States
- Volunteers
- 63 people
- Sponsor
- AbbVie
Pancreatic Insufficiency
Pancreatic Insufficiency Secondary to Tobacco Exposure
Pancreatic insufficiency is a condition in which there is a decrease in the production and release of enzymes made in the pancreas, which causes nutrient malabsorption.
- Trial name
- NCT01988350
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Emory University