Clinical trials: Pancreatic Mass
Lung Cancer, Pancreatic Cancer
Nutritional Problems in Pallative Cancer
The aim of this study is to investigate those nutritional problems contributing to loss of lean body mass in lung and pancreas cancer patients in chemotherapy.
- Trial name
- NCT04846985
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Jens Rikardt Andersen
Cystic Fibrosis
Breath Analysis in in Adults With Cystic Fibrosis (CF)
Exploratory comparative evaluation of exhaled breath composition in cystic fibrosis patients with age and gender-matched healthy adults in order to identify a disease-specific exhaled breath pattern as well as to gain insight…
- Trial name
- NCT02209571
- Testing
- Venous blood markers
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pancreatic Neoplasm
Comparison of Two Fine Needle Biopsy Needles for Solid Pancreatic Masses
This is a randomized prospective clinical study comparing the Acquire Biopsy Device to SharkCore Biopsy Device.
- Trial name
- Expect (NCT02910960)
- Testing
- Acquire EUS Biopsy Device, SharkCore Biopsy System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AdventHealth
Pancreatic Mass
Comparing the Diagnostic Efficacy of Different Suction Techniques for EUS-FNB of Pancreatic Solid Lesions
There are many factors that can affect the diagnostic yield of EUS-FNA, including lesion factors, the endoscoist experience, the needle size, the number of needle passes, and the suction technique.
- Trial name
- NCT04100941
- Testing
- standard suction, slow pull, wet suction
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Chronic Respiratory Diseases, Cystic Fibrosis
Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases
Assessment of cardiovascular disorders using echocardiography and arterial stiffness; comparative noninvasive assessment of volatile organic compound (eVOC) exhale breath patterns in patients with different chronic respiratory…
- Conditions
- Chronic Respiratory Diseases, Cystic Fibrosis, Lymphangioleiomyomatosis, Hypersensitivity Pneumonitis
- Trial name
- NCT05727852
- Testing
- Breath test using the Compact PTR-TOF-MS, Portable cardiac monitor "CardioQvark", Assessment of arterial stiffness using the VaSera VS-1500N
- Where
- Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Stage III Breast Cancer, Stage IV Breast Cancer
Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs
The primary objective of this study, sponsored by Travera in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using…
- Conditions
- Stage III Breast Cancer, Stage IV Breast Cancer, Stage III Lung Cancer, Stage IV Lung Cancer
- Trial name
- NCT04985357
- Sponsor
- Travera Inc
Pancreatic Cancer, Lymphadenopathy
Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle
The primary objective of this proposed prospective randomized, multi-center study is to evaluate the capability of the new 22G SharkCore™ needle to obtain tissue specimens and to compare its performance against the standard 22G…
- Conditions
- Pancreatic Cancer, Lymphadenopathy, Cholangiocarcinoma
- Trial name
- NCT02872831
- Testing
- 22G SharkCore™ needle, 22G BNX EUS-FNA Needle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cancer, Cancer of Pancreas
Muscle Dysfunction in Gastrointestinal or Hepatobiliary Cancer
PURPOSE: To determine the prognostic properties of a comprehensive evaluation of body composition and physical function in patients with GI-HEP cancer from point of diagnosis and throughout the treatment trajectory.
- Conditions
- Cancer, Cancer of Pancreas, Cancer of Liver, Cancer of Esophagus
- Trial name
- NCT03347162
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pancreatic Cancer, Metastatic Breast Cancer
Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced Cancers
Among patients with advanced (metastatic) cancers, detailed characterizations of the tumor utilizing genomic and proteonomic techniques may help guide treatment.
- Conditions
- Pancreatic Cancer, Metastatic Breast Cancer, Metastatic Lung Cancer, Metastatic Colon Cancer
- Trial name
- NCT03073473
- Testing
- NantHealth GPS Cancer Test
- Where
- 10 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cota Inc.
Type I Diabetes
Assessment of Beta Cell Mass in Type 1 Diabetes With 11C-Dihydrotetrabenazine and PET Scan
This study will test dihydrotetrabenazine, or 11C-DTBZ, a radioactive tracer, as an imaging agent in positron emission tomography (PET).
- Trial name
- NCT00351650
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Autoimmune Pancreatitis, Pancreatic Ductal Adenocarcinoma (PDAC)
AI-Assisted Differentiation of Autoimmune Pancreatitis and Pancreatic Cancer Using EUS: A Multicenter Ambispective Study
Focal autoimmune pancreatitis (f-AIP) and pancreatic ductal adenocarcinoma (PDAC) exhibit substantial overlap in clinical manifestations and imaging features, posing a major diagnostic challenge in pancreatic diseases.
- Trial name
- NCT07900776
- Volunteers
- 690 people
- Sponsor
- Ruijin Hospital
Pancreatic Neoplasm, Magnetic Resonance Imaging
MRE for Diagnosis of Pancreatic Masses
Pancreatic ductal adenocarcinoma (PDAC) accounts for 85-95% of pancreatic cancer and is one of the deadliest tumors in the world, with a survival rate of less than 8%, and identifying key prognostic or predictive factors…
- Trial name
- MREDPCM (NCT06526442)
- Testing
- magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yu Shi
Type 1 Diabetes, Pregnancy
Pancreatic Islet Mass in Pregnancy in Type 1 Diabetes
Type 1 diabetic women have a decrease in insulin requirements during early pregnancy. Preliminary evidence suggests this decrease may be secondary to the regeneration of pancreatic B-cells during pregnancy During the second and…
- Trial name
- NCT00548522
- Where
- 2 sites in Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Pancreas Cancer, Pancreatic Adenocarcinoma
Study Comparing Pancreatic EUS-FNB With the 20-gauge Procore® and the 22-gauge Acquire® Needles
Multicenter randomized prospective study Criteria for inclusion: Patients admitted for EUS-FNB of a pancreatic mass Goals of the study: To compare the results of blinded punctures for suspicion of pancreatic tumor performed under…
- Trial name
- HISTOPAN (NCT03567863)
- Testing
- 20-GAUGE PROCORE® first, then 22-GAUGE ACQUIRE®, 22-GAUGE ACQUIRE® first, then 20-GAUGE PROCORE®
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Société Française d'Endoscopie Digestive
Pancreatic Neoplasm
Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses
This is a randomized prospective clinical study comparing a fine needle biopsy device and an aspiration needle.
- Trial name
- Expect (NCT02911974)
- Testing
- Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- AdventHealth
Pancreatectomy, Diabetes Mellitus Type 2
Clinical, Oncologic, and Metabolic Effects of Pancreatic Mass Loss After Pancreatectomy in Non-Diabetic Patients
This study will examine how removal of part or all of the pancreas affects blood sugar control, metabolism, and clinical outcomes over time.
- Conditions
- Pancreatectomy, Diabetes Mellitus Type 2, Pancreatic Neoplasms
- Trial name
- DCP-NDM (NCT07608055)
- Where
- Italy
- Volunteers
- 579 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pancreatic Ductal Adenocarcinoma (PDAC)
A Study Looking at Whether a Nutritional Composition Can Help People With Pancreatic Cancer Stay Stronger and Better Tolerate Chemotherapy
The HEXCARE-PDAC study is a Phase III, randomized, double-blind, controlled, multicenter trial evaluating the effectiveness of a cancer-specific oral nutritional supplement in preserving skeletal muscle mass and improving…
- Trial name
- HEXCARE-PDAC (NCT07870421)
- Testing
- A novel cancer-specific high energy high protein medical nutrition solution, A commercially available isocaloric isonitrogenous medical nutritional solution.
- Volunteers
- 216 people
- Sponsor
- Nutricia Research
Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength
Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life
The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are: Is it feasible to measure hand grip strength as part of a clinic…
- Trial name
- PanFit (NCT07255001)
- Testing
- Hand grip strength assessments using a dynamometer
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Clear Cell Renal Cell Cancer (ccRCC), Pancreatic Ductal Adenocarcinoma (PDAC)
A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors
The main purpose of Part A of the study is to evaluate safety, tolerability and tracer uptake after a single intravenous (IV) administration of [68Ga]Ga-DPI-4452 for each tumor type such as clear cell renal cell cancer (ccRCC)…
- Conditions
- Clear Cell Renal Cell Cancer (ccRCC), Pancreatic Ductal Adenocarcinoma (PDAC), Colorectal Cancer (CRC), Urothelial Carcinoma (UC)
- Trial name
- NCT05706129
- Testing
- [68Ga]Ga-DPI-4452, [177Lu]Lu-DPI-4452
- Where
- 10 sites in Australia, France
- Volunteers
- 270 people
- Sponsor
- Lumara Bio Oncologics GmbH
Pancreatic Cancer, Bile Duct Cancer
A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers
This registry will collect data from patients routinely undergoing an ERCP and Cellvizio endomicroscopy procedure (and optionally an additional cholangiopancreatoscopy procedure) due to suspected pancreatic or bile duct cancer.
- Trial name
- NCT00779688
- Testing
- Probe-based confocal laser endomicroscopy
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 130 people
- Sponsor
- Mauna Kea Technologies