Clinical trials: Pancreatitis, Acute
Recurrent Acute Pancreatitis
Recurrence of Acute Alcoholic Pancreatitis
Previously our retrospective study showed that almost half of the patients with acute alcoholic pancreatitis had a recurrent attack in the long-term, mild pancreatitis and young age being risk factors for recurrence.
- Trial name
- NCT00523874
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Tampere University
Severe Acute Pancreatitis
Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis
The purpose of this study is to comparatively assess the potential antiinflammatory effects of intravenous lipid emulsions rich in omega 3 polyunsaturated fatty acids and olive oil versus intravenous lipid emulsions made…
- Trial name
- NCT01376817
- Testing
- Fat emulsion with MCT, LCT, olive oil and omega 3 fatty acids, Fat emulsion with MCT and LCT
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Pancreatitis
"NSAIDs vs. Opiates: Which is More Effective in Managing Pain in Mild to Moderate Acute Pancreatitis?
Acute pancreatitis is a painful and potentially life-threatening condition that affects the pancreas, a glandular organ responsible for producing digestive enzymes and hormones.
- Trial name
- NCT05756504
- Testing
- Ketorolac, Tramadol
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Hayatabad Medical Complex
Acute Pancreatitis, Telemedicine
Remote Home Monitoring Acute Pancreatitis
Acute pancreatitis is an inflammation of the pancreas which causes abdominal pain and is the most common gastro-intestinal reason for acute hospitalization in Western countries.
- Conditions
- Acute Pancreatitis, Telemedicine, Healthdot, Patient Discharge
- Trial name
- REMAP (NCT05501314)
- Testing
- Early discharge with remote home monitoring.
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Rijnstate Hospital
Post-ERCP Acute Pancreatitis
Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis
This study will explore the efficacies of several practical short-term (peri-procedural) intravenous fluid regimens in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).
- Trial name
- STRIPE (NCT06260878)
- Testing
- Intravenous Ringer's lactate
- Where
- Canada
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection
Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis
This clinical trial aims to learn if a combination of Dextran 40 and Ringer's lactate solution can improve fluid resuscitation in mild and moderate acute pancreatitis (AP) and prevent complications.
- Conditions
- Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection, Fluid Resuscitation
- Trial name
- NCT06835023
- Testing
- Ringer lactate (RLS), Dextran+Ringer Lactat(D+RLS)
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Satu Mare County Emergency Hospital
Post-ERCP Acute Pancreatitis, NSAIDs
Prevention of Post-ERCP Pancreatitis by Indomethacin vs Diclofenac
Post-ERCP pancreatitis (PEP) is the most common complication after ERCP, which was associated with occasional mortality, prolonged hospital days and increased health costs.
- Conditions
- Post-ERCP Acute Pancreatitis, NSAIDs, Indomethacin, Diclofenac
- Trial name
- NCT05947461
- Testing
- 100mg diclofenac, 100mg indomethacin
- Where
- 11 sites in China
- Volunteers
- 1,204 people
- Sponsor
- Air Force Military Medical University, China
Acute Necrotizing Pancreatitis, Pancreatic Exocrine Insufficiency
Pancreatic Enzyme Replacement in Acute Necrotizing Pancreatitis
In this multicenter, double blinded, placebo-controlled, 1:1 parallel group RCT, the investigators propose to evaluate the impact of pancreatic exocrine replacement therapy on patients with acute necrotizing pancreatitis (ANP).
- Trial name
- PERiANP (NCT07441824)
- Testing
- Pancreatic enzyme capsules
- Where
- 4 sites in India
- Volunteers
- 140 people
- Sponsor
- Asian Institute of Gastroenterology, India
Acute Pancreatitis
The Effect of Dietary Fat Content on the Recurrence of Pancreatitis
This trial aims to test the effects of two different diets on the recurrence of acute pancreatitis, and acute pancreatitis associated mortality.
- Trial name
- EFFORT (NCT04761523)
- Testing
- Dietary intervention: reduced fat diet, Dietary intervention: standard healthy diet
- Where
- Hungary
- Volunteers
- 384 people
- Sponsor
- University of Pecs
Pancreatitis, Acute, Bleeding
Quick Large Balloon Dilatation for Removal of Large Bile Duct Stones (SHODBADI)
ESGE guidelines suggests 30-60 seconds endoscopic large balloon papillary dilation from the disappearance of the waist of the papilla.
- Conditions
- Pancreatitis, Acute, Bleeding, Cholangitis
- Trial name
- SHODBADI (NCT05061680)
- Testing
- endoscopic short duration papillary large balloon dilation
- Where
- 2 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Helsinki University Central Hospital
Patients With Acute Pancreatitis
Early Treatment With Dexamethasone in Mild Acute Pancreatitis
This pilot trial will evaluate the following in patients with acute pancreatitis: 1. Safety profile of early treatment with intravenous dexamethasone 2.
- Trial name
- NCT01247961
- Testing
- Dexamethasone acetate
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Acute Pancreatitis
Early Oral Carbohydrate Solution vs Clear Liquid Diet in Acute Pancreatitis
Background: Acute pancreatitis (AP) is an inflammatory condition associated with increased metabolic demands and negative nitrogen balance, making early nutritional support a critical component of management.
- Trial name
- NCT07375186
- Testing
- Oral Carbohydrate Solution, Clear Liquid diet
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Jinnah Hospital
Pancreatitis, Pancreatitis, Acute Necrotizing
Dual-scopic Pancreatic Necrosectomy (DPN)
The LPN procedure is performed under general anesthesia. The transperitoneal access to peripancreatic space is via the gastro-colic ligament and greater omentum, effusion and pus is removed by laparoscopic forceps and suction.
- Conditions
- Pancreatitis, Pancreatitis, Acute Necrotizing, Pancreatic Diseases
- Trial name
- NCT04443595
- Testing
- Dual-scopic pancreatic necrosectomy（DPN）
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First People's Hospital of Hangzhou
Severe Acute Pancreatitis, Intra-abdominal Hypertension
Efficacy and Safety of Da-Cheng-Qi Decoction in Severe Acute Pancreatitis
This single-center prospective randomized controlled trial evaluated Da-Cheng-Qi Decoction (DCQD) as the acute-stage intervention of an integrated traditional Chinese and Western medicine whole-stage treatment protocol for severe…
- Trial name
- NCT07816900
- Testing
- Da-Cheng-Qi Decoction Plus Standard Western Treatment, Standard Western Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Necrotizing Pancreatitis
Endoscopic Large Caliber Drainage vs. Complete Necrosectomy for Treatment of Walled-off Pancreatic Necrosis
The purpose of this study is to determine optimal treatment strategies for symptomatic walled-off pancreatic necrosis( WON).
- Trial name
- NCT02564965
- Testing
- Double Pigtail Plastic Stent, AXIOS Metal Stent
- Sponsor
- Mayo Clinic
Severe Hypertriglyceridemia (sHTG)
Safety and Efficacy Following Repeat-Dose of Evinacumab (Anti-ANGPTL3) in Patients With Severe Hypertriglyceridemia (sHTG) at Risk for Acute Pancreatitis
The primary objective is to determine the change in Triglyceride (TG) levels following 12 weeks of repeated Intravenous (IV) doses of evinacumab.
- Trial name
- NCT03452228
- Testing
- evinacumab
- Where
- 17 sites in United States, Canada and 2 more
- Volunteers
- 52 people
- Sponsor
- Regeneron Pharmaceuticals
Acute Pancreatitis
Early High-volume Continuous Veno-venous Hemofiltration for Patients With Severe Acute Pancreatitis
The purpose of this study is to determine the effect and safety of early high-volume continuous veno-venous hemofiltration for patients with severe acute pancreatitis.
- Trial name
- EHVCVVHSAP (NCT01595672)
- Testing
- AN69 hemofilter, conventional treatments
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Air Force Military Medical University, China
Pancreatic Cancer, Diagnose Disease
AI-Powered Precision Decision-Making for Pancreatic Diseases
This multicenter clinical trial evaluates an artificial intelligence (AI) system designed to assist in the diagnosis and management of pancreatic diseases.
- Conditions
- Pancreatic Cancer, Diagnose Disease, IPMN, Pancreatic, Pancreatic Cystic Lesions
- Trial name
- NCT07439757
- Testing
- Diagnosis by Artificial Intelligence model
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis (AP), Diabetes Mellitus
Hyperglycemia and Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2.
- Trial name
- NCT06590233
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Changzheng Hospital
Acute Biliary Pancreatitis
Early EUS in Acute Biliary Pancreatitis
Acute biliary pancreatitis (ABP) is a potentially life-threatening condition caused by common bile duct (CBD) stones or sludge, which requires prompt diagnosis and treatment by endoscopic removal of the material.
- Trial name
- NCT02430285
- Testing
- Endoscopic Ultrasound, Olympus 180 series echoendoscope
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- Istituto Clinico Humanitas