Clinical trials: Pancreatitis, Autoimmune
Pancreatic Cancer, Pancreatitis
Validation of Joint-AI in Diagnosing Pancreatic Solid Lesions
This clinical trial aims to learn if a multimodal artificial intelligence (AI) model can enhance the diagnosis of pancreatic solid lesions. The main questions it aims to answer are: 1.
- Conditions
- Pancreatic Cancer, Pancreatitis, Pancreatic Neuroendocine Neoplasms (pNETs), Autoimmune Pancreatitis
- Trial name
- NCT06753318
- Testing
- The assistance of the Joint-AI model, The assistance of the interpretable Joint-AI model
- Where
- China
- Volunteers
- 716 people
- Sponsor
- Huazhong University of Science and Technology
Retroperitoneal Fibrosis, Autoimmune Pancreatitis
Rituximab in IgG4-RD: A Phase 1-2 Trial
The primary objective of this study is to evaluate the safety and effectiveness of rituximab in IgG4-RD.
- Conditions
- Retroperitoneal Fibrosis, Autoimmune Pancreatitis, Sialadenitis, Pseudotumor
- Trial name
- NCT01584388
- Testing
- Rituximab
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic
Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions
We aim to develop an EUS-AI model which can facilitate clinical diagnosis by analyzing EUS pictures and clinical parameters of patients.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis
- Trial name
- NCT05476978
- Testing
- EUS-AI model
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Acute Pancreatitis
Assessment of the Different Etiological and Susceptibility Markers in Patients With Pancreatitis: Investigating IG4, Cytomegalovirus, Coxsackie- Virus, Genetic Polymorphism of Vitamin D Receptor Gene
Acute pancreatitis (AP) is a multifactorial disease. AP represents a significant number of hospital admissions. Most of the patients are admitted in an acute setting.
- Trial name
- NCT03830073
- Testing
- Measurement of VDR genetic polymorphism
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type 1 Diabetes (T1D), Latent Autoimmune Diabetes in Adult (LADA)
Building and Sustaining Exercise Habits for Adults With Type 1 Diabetes
The challenges of living with type 1 diabetes often stand in the way of getting enough exercise. Continuous blood sugar monitoring has revolutionized type 1 diabetes care but remains underutilized to sustainably support exercise…
- Conditions
- Type 1 Diabetes (T1D), Latent Autoimmune Diabetes in Adult (LADA), Pancreatitis
- Trial name
- NCT06967701
- Testing
- Exercise program, Self-monitoring
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Pancreas Neoplasm, Pancreatitis
EUS Shear Wave for Solid Pancreatic Lesions.
The diagnosis of pancreas diseases is based on a combination of clinical signs, symptoms, and laboratory tests, but mainly on imaging techniques such as computed tomography (CT) and magnetic resonance (MR).
- Conditions
- Pancreas Neoplasm, Pancreatitis, Pancreatitis, Acute, Pancreatitis, Chronic
- Trial name
- NCT05095831
- Testing
- Pancreas EUS shear wave, Pancreas EUS-elastography and EUS-guided biopsy
- Where
- Ecuador
- Volunteers
- 25 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Autoimmune Pancreatitis
CT Findings in Surgically Treated Focal Pancreatic Disease- A Retrospective Study
To retrospectively investigate CT imaging features of autoimmune and chronic pancreatitis (AIP and CP) mimicking pancreatic ductal adenocarcinoma in surgically resected patients.
- Trial name
- NCT06699667
- Testing
- Computed tomography
- Volunteers
- 41 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type 1 Diabetes (T1D), Diabetes Secondary to Pancreatitis
Digital Mindfulness for Young Adults With Type 1 Diabetes
The purpose of this research study is to test a mindfulness app called Calm Health among young adults with type 1 diabetes or other absolute insulin deficiency diabetes.
- Trial name
- NCT07062887
- Testing
- Mindfulness app
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Type 1 AIP
Inebilizumab for the Treatment of Patients With Type 1 Autoimmune Pancreatitis
Autoimmune pancreatitis (AIP) is an immune-related inflammatory disease of the pancreas. Relapse can occur after treatment, and long-term treatment with glucocorticoids and conventional immunosuppressants can cause significant…
- Trial name
- NCT07862075
- Testing
- Inebilizumab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruijin Hospital
Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease
Treatment of IgG4-Related Disease With Revlimid and Rituximab
Among persons with Immunoglobulin G subclass 4 Related Disease (IgG4)-related disease who have persistent or recurrent disease despite standard therapies, does combination therapy with rituximab and revlimid cause a sustained…
- Conditions
- Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease, Autoimmune Pancreatitis, IgG4-related Sclerosing Cholangitis
- Trial name
- TIGR2 (NCT02705638)
- Testing
- Rituximab, Lenalidomide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Type 1 AIP
A Trial on the Remission Rates of Type I Autoimmune Pancreatits With High-risk of Recurrence
Autoimmune pancreatitis (AIP) is an autoimmune disease with low incidence rate and involving the pancreas. In China, type I AIP is predominant. Glucocorticoids (GC) have a significant therapeutic effect.
- Trial name
- AIP；MMF (NCT06468709)
- Testing
- Glucocorticoids, Glucocorticoids+MMF
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Ruijin Hospital
Autoimmune Pancreatitis
EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis
The goal of this prospective study is to evaluate the feasibility of the Core Biopsy Needle with reverse bevel (Procore TM) in diagnosing autoimmune pancretitis
- Trial name
- NCT01774513
- Testing
- Procore-Needle
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Autoimmune Pancreatitis Type 1, Autoimmune Pancreatitis Type 2
Autoimmune Pancreatitis, Pancreatic and Extrapancreatic cAnceR (AiPPEAR)
The goal of this observational, retrospective study is to learn about cancer risk in autoimmune pancreatitis (AIP) patients. The main questions it aims to answer are: Do patients with AIP have higher incidence of cancer in…
- Trial name
- AiPPEAR (NCT06328101)
- Volunteers
- 1,000 people
- Sponsor
- University Medical Center Goettingen
Oral Microbiota, Pancreatitis
The Characteristics of Oral Microbiota in Chronic Pancreatitis and Autoimmune Pancreatitis
There are more than 700 different bacteria colonized in human oral cavity, which are collectively referred to as oral microbiota.
- Conditions
- Oral Microbiota, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT07015580
- Testing
- 16S rRNA sequencing
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Type 1 Diabetes, Latent Autoimmune Diabetes in Adults
Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes
The challenges of living with type 1 diabetes often stand in the way of getting enough exercise. Continuous blood sugar monitoring has revolutionized type 1 diabetes care but remains underutilized to sustainably support exercise…
- Conditions
- Type 1 Diabetes, Latent Autoimmune Diabetes in Adults, Pancreatitis
- Trial name
- NCT06098729
- Testing
- Digital Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Pancreatitis, Chronic, Autoimmune Disease
Pancreatic Duct Evaluation in Autoimmune Pancreatitis: MR Pancreatography
A prospective intra-individual study to compare the image quality of magnetic resonance (MR) pancreatography at 3.0 T and 1.5 T in patients with autoimmune pancreatitis.
- Trial name
- NCT01773031
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Jae Ho Byun
Adenocarcinoma, Neuroendocrine Tumors
EchoTip AcuCore Post-Market Clinical Study
The purpose of collecting this data is to continue to learn more about the EchoTip AcuCore and the device's ability to produce the desired favorable effect and if there are any undesired outcomes that may be related to the…
- Conditions
- Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma
- Trial name
- NCT06358001
- Testing
- EchoTip AcuCore
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- Cook Research Incorporated
Autoimmune Pancreatitis
Diagnostic Yield of FNA Needle and FNB Needle for Autoimmune Pancreatitis
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 19G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device for…
- Trial name
- NCT03753815
- Testing
- 19G FNA needle, 20G FNB needle
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Peking Union Medical College Hospital