Clinical trials: Pancreatitis
Walled Off Pancreatic Necrosis
AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study
To demonstrate safety and effectiveness of lumen-apposing metal stents for resolution of walled off pancreatic necrosis (WONs) in patients with WONs with solid component >30%.
- Trial name
- NCT03525808
- Testing
- AXIOS
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Boston Scientific Corporation
Acute Pancreatitis
Clinical Usefulness of Cortisol, Antinuclear Antibodies and High-sensitivity C-reactive Protein in Acute Pancreatitis
Acute pancreatitis (AP) is a potentially life-threatening disease with varying severity of presentation. Nearly 60%-80% of all cases of AP in developed countries are attributable to either gallstone disease or alcohol abuse.
- Trial name
- NCT03830060
- Testing
- Measurement of cortisol
- Volunteers
- 50 people
- Sponsor
- Assiut University
Alcoholic Cirrhosis
EUS Based Prevalence of Chronic Pancreatitis in Alcoholic Cirrhosis
Alcohol is the common precipitating factor for both cirrhosis of liver as well as alcohol related chronic pancreatitis. However, in real life clinical setting, clinicians do not frequently see many cases of symptomatic…
- Trial name
- NCT04245189
- Testing
- Endoscopic ultrasound for detection of Chronic pancreatitis
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Asian Institute of Gastroenterology, India
Acute, Pancreatitis
Soluble Triggering Receptor Expressed on Myeloid Cells in Severe Acute Pancreatitis
Early diagnosis of secondary infection of necrotic tissue in severe acute pancreatitis is extremely important. The investigators evaluated whether the level of soluble TREM-1 (sTREM-1) in fine needle aspiration (FNA) fluid from…
- Trial name
- STREM-1 (NCT01193413)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Changhai Hospital
Pancreatitis, Acute
Changes in High Sensitive C Reactive Protien With Different Treatment Modalities in Acute Pancreatitis
changes in high sensitive C reactive protien with different treatment modalities in acute pancreatitis
- Trial name
- NCT03740685
- Testing
- High sesitive C reactive protien
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Acute Pancreatitis
Searching the Best Prognostic Factor in Out Come Evaluation in Patients With Acute Pancreatitis Admitted at Assiut University Hospitals
Acute pancreatitis (AP) is rapid-onset inflammation of the pancreas that varies in severity from a self-limiting mild illness to rapidly progressive multiple organ failure.
- Trial name
- NCT03259880
- Volunteers
- 100 people
- Sponsor
- Fady Refaat Edwar Nasrallah
Pancreatectomy, Hyperamylasemia
Incidence and Clinical Impact of Serum Hyperamylasemia (POH) After Pancreatectomy on Postoperative Outcome and Patient Safety
Recent evidence suggests that postoperative hyperamylasemia (POH) is a predictor of morbidity after pancreatectomy. This is based on the assumption that pancreatitis after pancreatectomy (PPAP) is a major trigger for the…
- Conditions
- Pancreatectomy, Hyperamylasemia, Pancreatitis, Acute
- Trial name
- HYPPO (NCT06126601)
- Testing
- Pancreatectomy
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technische Universität Dresden
Pancreatitis
PRIMARY NEEDLE KNIFE FISTULOTOMY
Evaluate the outcomes of NKF as an initial method for biliary access.
- Trial name
- NCT06452875
- Testing
- Primary Needle Knike Fistulotomy
- Where
- Portugal
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Minho
Chronic Pancreatitis
Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) Symptoms
Exocrine Pancreatic Insufficiency (EPI) is a condition where pancreatic enzyme quantity or activity is reduced below threshold needed for normal digestion. Symptoms include bloating, flatulence, diarrhea and steatorrhea.
- Trial name
- CisCP (NCT04949828)
- Testing
- CREON
- Where
- 6 sites in United States
- Volunteers
- 63 people
- Sponsor
- AbbVie
Chronic Pancreatitis
Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis
Primary objective: To describe and compare the safety and efficacy of treatment with AAT in chronic pancreatitis patients who undergo total pancreatectomy and islet autotransplantation (TP-IAT).
- Trial name
- NCT02947087
- Testing
- Prolastin-C
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina
Exocrine Pancreatic Insufficiency, Chronic Pancreatitis
Safety and Efficacy Study of Viokase® 16 for the Correction of Steatorrhea
This study assesses the efficacy and safety of Viokase® 16 for the correction of steatorrhea (malabsorption of dietary fats) in patients with a history of exocrine pancreatic insufficiency (EPI) due to chronic pancreatitis (CP)…
- Conditions
- Exocrine Pancreatic Insufficiency, Chronic Pancreatitis, Pancreatectomy
- Trial name
- NCT00559364
- Testing
- Viokase® 16, Proton pump inhibitor (PPI), Omeprazole
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 50 people
- Sponsor
- Forest Laboratories
Acute Pancreatitis
Post Acute Pancreatitis Pancreatic Exocrine Insufficiency
This study is a proposed a comprehensive prospective assessment of exocrine pancreatic insufficiency (EPI), nutritional status, and quality of life (QOL) during the early re-feeding phase, at 3 months, and 12 months following an…
- Trial name
- PAPPEI (NCT03063398)
- Testing
- No intervention, this is an observational study
- Where
- 3 sites in United States
- Volunteers
- 196 people
- Sponsor
- Ohio State University
Acute Necrotizing Pancreatitis
Tracking ENcapsulation of Pancreatic Collections in Acute Necrotizing Pancreatitis
The goal of this study is to investigate the encapsulation of fluid collections in patients with ANP using serial MRI. The main questions it aims to answer are: Evaluating the timing of encapsulation of necrotic fluid collection…
- Trial name
- NCT05716633
- Testing
- MRI
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pancreatitis
Effects of Early Stage Mini-invasive Abdominal Drainage on Complications and Prognosis of SAP
This study aims to standardized the process of mini-invasive abdominal draniage of SAP in early stage.To determine the indications and occasion.
- Trial name
- NCT02002793
- Testing
- Early stage abdominal drainage, Late stage abdominal drainage
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly used for the diagnosis and treatment of pancreatobiliary diseases.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07637721
- Testing
- The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula
- Where
- 3 sites in China
- Volunteers
- 410 people
- Sponsor
- Zhejiang University
Pancreatitis, Pancreatitis, Acute
Corticosteroids to Treat Pancreatitis
This research is being done to determine if the administration of a short course of intravenous hydrocortisone, an anti-inflammatory medication, to patients with severe acute pancreatitis will improve their clinical outcomes and…
- Conditions
- Pancreatitis, Pancreatitis, Acute, Corticosteroid, Hydrocortisone
- Trial name
- CRISP (NCT05160506)
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Beth Israel Deaconess Medical Center
Post-ERCP Acute Pancreatitis
Papillary Epinephrine Injection vs Rectal Indomethacin
Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common and one of the most undesirable major adverse events after endoscopic retrograde cholangiopancreatography (ERCP), causing significant…
- Trial name
- PEIR-PEP (NCT07173179)
- Testing
- Epinephrine injection, Indomethacin
- Where
- Turkey (Türkiye)
- Volunteers
- 504 people
- Sponsor
- Duzce University
Post-ERCP Acute Pancreatitis
Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis is a well-known and sometimes life-threatening complication of ERCP. Both LR and rectal indomethacin have shown benefit in preventing post-ERCP pancreatitis.
- Trial name
- IND+LRPEP (NCT02641561)
- Testing
- Indomethacin, Lactated Ringer's Solution, Normal Saline
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Cholelithiasis, Choledocholithiasis
Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy
This study aims to evaluate post-operative pain in single-incision laparoscopic cholecystectomy (SILC) versus the conventional four port technique (LC).
- Conditions
- Cholelithiasis, Choledocholithiasis, Cholecystolithiasis, Pancreatitis
- Trial name
- NCT01824186
- Testing
- SILC, LC
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Sphincter of Oddi Dysfunction
Evaluating Predictors & Interventions in Sphincter of Oddi Dysfunction
The Evaluating Predictors \& Interventions in Sphincter of Oddi Dysfunction(SOD) study (EPISOD) is a randomized sham-controlled study of biliary and pancreatic sphincterotomy as treatment for patients with pain after…
- Trial name
- EPISOD (NCT00688662)
- Testing
- ERCP with sphincterotomy, ERCP without sphincterotomy
- Where
- 7 sites in United States
- Volunteers
- 214 people
- Sponsor
- Medical University of South Carolina