Clinical trials: Pancreatitis
Pancreatitis,Acute Necrotizing
Open Surgery for Necrotizing Pancreatitis
Retrospective analysis of the cases of traditional open surgery for acute necrotizing pancreatitis, with evaluation of indications for surgery, intraoperative findings, mortality rate and risk factors of mortality.
- Trial name
- NCT04673552
- Testing
- laparotomy
- Where
- Russia
- Volunteers
- 146 people
- Sponsor
- Northern State Medical University
Deep Biliary Cannulation
The Use of Guide Wire in Biliary Cannulation: Angled or Straight Tipped Guide Wire?
The purpose of the study is to prospectively evaluate the deep biliary cannulation in ERCP with the angled tipped guide wire or the straight tipped guide wire.
- Trial name
- NCT01002404
- Testing
- angled and straight tipped guide wire
- Where
- Finland
- Volunteers
- 164 people
- Sponsor
- Turku University Hospital
Pancreatitis, ERCP Surgery
Cold Water Irrigation Therapy as an Adjunct to Indomethacin for Post-Endoscopic Retrograde Cholangiopancreatography(ERCP) Pancreatitis
This study is designed to learn whether rinsing the papilla with cold water at the end of an ERCP procedure, in addition to standard medicine, can help lower the chance of developing pancreatitis, which is the most common major…
- Trial name
- NCT07330284
- Testing
- Cold water, Warm water
- Where
- United States
- Volunteers
- 950 people
- Sponsor
- University of Kansas Medical Center
Bacterial Infections and Mycoses, Appendicitis
Doripenem in the Treatment of Complicated Intra-Abdominal Infections
The purpose of this study is to compare the clinical response rates of doripenem versus a comparator antibiotic in treatment of hospitalized patients with complicated intra-abdominal infections.
- Conditions
- Bacterial Infections and Mycoses, Appendicitis, Cholecystitis, Pancreatitis
- Trial name
- NCT00210938
- Testing
- Doripenem
- Volunteers
- 478 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pancreatic Diseases, Pancreatic Neoplasms
DNA Promoter Hypermethylation as a Blood Based Maker for Pancreatic Cancer
The objectives of this project are to test whether alteration in DNA hypermethylation in plasma is: a diagnostic marker for pancreatic cancer a prognostic marker for pancreatic cancer a marker for recurrence of pancreatic cancer…
- Conditions
- Pancreatic Diseases, Pancreatic Neoplasms, Pancreatitis
- Trial name
- NCT02079363
- Testing
- No interventions, this is an observational study
- Where
- Denmark
- Volunteers
- 330 people
- Sponsor
- Aalborg University Hospital
Chronic Pancreatitis, Complication
The Natural History of Chronic Pancreatitis
Chronic pancreatitis (CP) is a disease characterized by inflammation and their replacement by fibrotic tissue. The destruction of pancreatic function and structure are the main complications.
- Conditions
- Chronic Pancreatitis, Complication, Risk Factors
- Trial name
- NCT03324698
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Changhai Hospital
Pancreatitis, Cholangitis
The Patency Period of the New Plastic Anti-reflux Biliary Stent
The aim of this study is to determine the average patency period of the new anti-reflux biliary stent on patients with malignant bile duct strictures and to determine if this stent remains patent for a longer period of time…
- Trial name
- NCT01142921
- Testing
- Anti-reflux Tannenbaum biliary stent, Ordinary Tannenbaum biliary stent
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Surgery, Pancreatitis
Active Versus Non Active Drainage for the Treatment of Infected Intra-abdominal Collection
The Percutaneous drainage of symptomatic intra-abdominal collection (primary or secondary to surgery)is the treatment of choice in the absence of peritonitis signs.
- Conditions
- Surgery, Pancreatitis, Diverticulitis, Appendicitis
- Trial name
- NCT01513421
- Testing
- Percutaneous drainage of intra-abdominal collection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Exocrine Pancreatic Insufficiency
Phase III ALTU-135 CP Safety Trial
This is an open-label, single-arm clinical study investigating the long-term safety of ALTU-135 treatment in Chronic Pancreatitis (CP) patients with exocrine Pancreatic Insufficiency (PI).
- Trial name
- DIGEST CP (NCT00500084)
- Testing
- Liprotamase
- Where
- 11 sites in United States
- Volunteers
- 39 people
- Sponsor
- Anthera Pharmaceuticals
Pancreatic Neoplasms, Biliary Tract Neoplasms
Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
Pancreaticojejunostomy is the key procedure of pancreaticoduodenectomy. The aim of our study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "nonstented stump-closed pancreaticojejunostomy" in…
- Conditions
- Pancreatic Neoplasms, Biliary Tract Neoplasms, Pancreatitis, Chronic, Duodenal Neoplasms
- Trial name
- NCT01731821
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Fudan University
Pancreatic Ductal Adenocarcinoma (mPDAC), Pancreatic Head Tumour
Immunoparalysis After Pancreaticoduodenectomy
By 2030, pancreatic adenocarcinoma could become the second leading cause of cancer-related death in France. To date, Pancreaticoduodenectomy (PD) is the standard treatment for resectable adenocarcinoma of the pancreatic head.
- Conditions
- Pancreatic Ductal Adenocarcinoma (mPDAC), Pancreatic Head Tumour, Pancreatic Fistula
- Trial name
- ImPaHLA (NCT07144917)
- Testing
- mHLA-DR analysis
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Endoscopic Retrograde Cholangiopancreatography
Does Pancreatic Stent Decrease the Risk of Pancreatitis After Pancreatic Sphincterotomy for Difficult Cannulation?
The purpose of the study is to compare the risk of PEP after pancreatic sphincterotomy performed for difficult cannulation in a group of patients with and in a group of patients without placement of a prophylactic pancreatic…
- Trial name
- NCT04408482
- Testing
- Biliary cannulation
- Where
- Finland
- Volunteers
- 268 people
- Sponsor
- Helsinki University Central Hospital
Autoimmune Pancreatitis
EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis
The goal of this prospective study is to evaluate the feasibility of the Core Biopsy Needle with reverse bevel (Procore TM) in diagnosing autoimmune pancretitis
- Trial name
- NCT01774513
- Testing
- Procore-Needle
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Choledocholithiasis, Gallstone Migration
Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration
Initial cholecystectomy with intraoperative cholangiogram, followed if required by ERCP, has been implemented at the investigators institution as the standard management strategy for patients at intermediate risk of common bile…
- Conditions
- Choledocholithiasis, Gallstone Migration, Cholecystitis, Gallstone Pancreatitis
- Trial name
- NCT02461147
- Testing
- Cholecystectomy with intraoperative cholangiogram
- Where
- Switzerland
- Volunteers
- 161 people
- Sponsor
- University Hospital, Geneva
Acute Pancreatitis
Home Monitoring Vs. Hospitalization for Mild Acute Pancreatitis
Acute pancreatitis accounts for a large number of hospital admissions every year. Some studies have shown that early oral feeding protocols are safe, and one previous study suggests the possibility of home care for mild acute…
- Trial name
- RHINO (NCT05473260)
- Testing
- Control, Experimental
- Where
- Spain
- Volunteers
- 308 people
- Sponsor
- Hospital Universitari de Bellvitge
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Pancreatitis, Pancreatic Exocrine Insufficiency
Investigation on the Current Situation and Risk Factors Analysis of Exocrine Insufficiency in Chronic Pancreatitis
Pancreatic exocrine insufficiency (PEI) is one of the common complications of chronic pancreatitis (CP). Mild to moderate PEI may present with atypical digestive tract symptoms such as abdominal distension and abdominal pain…
- Trial name
- CP-ESRF (NCT06946108)
- Testing
- Detection of Pancreatic Exocrine Function in Patients with Chronic Pancreatitis (CP)
- Where
- China
- Volunteers
- 1,101 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations
Pancreatitis remains the most common complication of ERCP, with the reported incidence ranging from 2% to 9%. Although 80% of cases are mild, a significant number of patients may develop severe pancreatitis, that means additional…
- Trial name
- NCT02928718
- Testing
- ERCP
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Hospital
Pancreas Cancer, Pancreatic Ductal Adenocarcinoma
Clinical Performance of Medical Device Software "Lipidica 1.0" for Processing Data Generated by Lipidomic Analysis in Pancreatic Cancer Screening
Software "Lipidica" is intended to be used for processing data generated by the in-house in vitro diagnostic medical device for lipidomic testing for the purpose of screening Pancreatic cancer (PaC) in the population at high risk…
- Conditions
- Pancreas Cancer, Pancreatic Ductal Adenocarcinoma, Hereditary Diseases, Pancreatitis, Chronic
- Trial name
- NCT06549725
- Testing
- software Lipidica, endoscopic ultrasonography, magnetic resonance
- Where
- 16 sites in Czechia
- Volunteers
- 419 people, healthy volunteers welcome
- Sponsor
- Lipidica, a.s.
Acute Pancreatic Necrosis, Acute Pancreatitis
EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial
A prospective, single arm, open label, multi-center, trial to evaluate the safety and effectiveness of the Interscope EndoRotor® Resection System in subjects requiring direct endoscopic necrosectomy (DEN) with walled off…
- Conditions
- Acute Pancreatic Necrosis, Acute Pancreatitis, Necrotizing Pancreatitis
- Trial name
- NCT03694210
- Testing
- EndoRotor Therapy
- Where
- 10 sites in United States, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- Interscope, Inc.