Clinical trials: Pancreatoduodenectomy
Pancreatic Cancer, Pancreatic Fistula
Anastomotic Techniques in Pancreaticoduodenectomy
There are two principal ways of draining the remnant of the pancreas back into the intestine after removal of the head of the pancreas for cancer. This can be performed either to the jejunum or to the stomach.
- Trial name
- PG/PJ (NCT00855985)
- Testing
- type of anastomosis after pancreaticoduodenectomy
- Where
- India
- Volunteers
- 312 people
- Sponsor
- Lakeshore Hospital
Pancreatic Neoplasms, Pancreatic Fistula
Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD
This prospective study evaluates whether preoperative endoscopic ultrasound elastography (EUS-E) can predict pancreatic texture during surgery and risk of postoperative pancreatic fistula (POPF) in 100 patients undergoing…
- Trial name
- EUS-E (NCT07139236)
- Testing
- Preoperative Endoscopic Ultrasound Elastography (EUS Elastography)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Pancreatic Fistula
One-layer Versus Two-layer Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
The aim of this study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "One-layer duct-to-mucosa pancreaticojejunostomy" in pancreatoduodenectomy, which could provide a feasible option to pancreatic…
- Trial name
- NCT02511951
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 114 people
- Sponsor
- The Second Hospital of Anhui Medical University
Pancreatic Cancer
Standardization of Surgery on the Pancreatic Cancer
This study was designed to test the hypothesis that more extensive nodal and soft-tissue clearance in patients with adenocarcinoma of the head of the pancreas would improve survival without an increase in morbidity and mortality.
- Trial name
- NCT00679913
- Testing
- Standard pancreatoduodenectomy, Extended pancreatoduodenectomy
- Where
- South Korea
- Volunteers
- 244 people
- Sponsor
- Seoul National University Hospital
Pancreatoduodenectomy, Pain Management
Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy
The goal of this clinical trial is to determine whether continuous nefopam administration, as part of a multimodal analgesia strategy, reduces opioid consumption and improves patient satisfaction after pancreatoduodenectomy.
- Conditions
- Pancreatoduodenectomy, Pain Management, Opioid Analgesia, Multimodal Analgesia
- Trial name
- NCT07423650
- Testing
- Nefopam 120mg/day infusion, Lidocaine Infusion, Peridural
- Where
- Romania
- Volunteers
- 93 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Omental Patch, Laparoscopic Pancreaticoduodenectomy
A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd
Pancreaticoduodenecotmy(PD) is considered as the standard procedure for peri-amplullary or pancreatic head tumors. Laparoscopic pancreaticoduodenctomy(LPD) has been reported with minimal invasive advantages, such as small…
- Conditions
- Omental Patch, Laparoscopic Pancreaticoduodenectomy, Pancreatic Fistula
- Trial name
- NCT04704882
- Testing
- omental patchwork
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhejiang Provincial People's Hospital
Surgery-Complications
Textbook and Survival Outcomes of MIPD in South Korea
The aim of this study was to investigate the current status of minimally invasive pancreatoduodenectomy (MIPD) in South Korea with regard to demographics, perioperative outcomes, risk factors for textbook outcome of pancreatic…
- Trial name
- NCT05975710
- Where
- South Korea
- Volunteers
- 1,552 people
- Sponsor
- Asan Medical Center
Reflux Esophagitis
Incidence of Reflux Esophagitis After Pancreaticoduodenectomy
Reflux esophagitis is a common complication following distal gastrectomy. According to the investigators preliminary data, an Roux-en--Y gastrointestinal reconstruction in pancreaticoduodenectomy is associated with higher rates…
- Trial name
- NCT01311908
- Testing
- Methods of gastrojejunostomy reconstruction
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Whipple Operation
Dachengqi Decoction for Enhancing Early Gastrointestinal Recovery After Whipple Surgery
To investigate the clinical efficacy of the traditional Chinese medicine formula Dachengqi Decoction in promoting early gastrointestinal function recovery after Whipple surgery, and to evaluate its impact on postoperative…
- Trial name
- NCT06948474
- Testing
- Dachengqi decoction, modified gastrointestinal dual-lumen feeding tube, Normal Saline (0.9% NaCl)
- Where
- China
- Volunteers
- 45 people
- Sponsor
- China-Japan Friendship Hospital
Pancreatic Cancer, Bile Duct Cancer
Effects of Preoperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
The purpose of this study is to determine whether preoperative immunonutrition is effective on infectious complication and Th1/Th2 differentiation in patients with pancreaticoduodenectomy.
- Trial name
- EPIPD (NCT01256034)
- Testing
- Oral IMPACT
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Chiba University
Periampullar Disease
Efficacy of Hemi-double-stapling Technique
Surgical stapler is used in all areas of surgical operation. Surgical stapler has been used in various surgical fields for a long time, so its stability has already been proven.
- Trial name
- NCT05088564
- Testing
- Hand-sewn, Hemi-double stapling
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Gangnam Severance Hospital
Closure of POPF After Pancreaticoduodenectomy
Route of Nutritional Support for Pancreatic Fistula
The aim of this study is to compare the closure rate of pancreatic fistula (PF) after pancreaticoduodenectomy (PD) under various types of nutrition.
- Trial name
- NCT01755260
- Testing
- Jejunostomy tube feeding
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Periampullary Tumors
Impact of Prophylactic Octreotide to Pancreatic Exocrine Secretion
This study aims to examine whether octreotide has an effect on inhibition of the exocrine secretion fo the pancreas, which might lower the rate of postoperative pancreatic fistula after pancreatoduodenectomy.
- Trial name
- NCT02920567
- Testing
- Octreotide
- Where
- South Korea
- Volunteers
- 282 people
- Sponsor
- Saint Vincent's Hospital, Korea
Pancreatic Cancer, Pancreatic Neoplasms
Monitoring of patIents With Microdialysis Following Pancreaticoduodenectomy
A pancreaticoduodenectomy is performed in patient with pancreatic cancer. The most common and serious complication is leakage between the intestine and the remnant pancreas after this procedure. It occurs in 20-30%.
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Biliary Tract Cancer, Duodenal Cancer
- Trial name
- MINIMUM (NCT03631173)
- Testing
- Surgical og radiological intervention, antibiotics
- Where
- Norway
- Volunteers
- 201 people
- Sponsor
- Oslo University Hospital
Pancreaticoduodenectomy
Isolated Pancreatic Loop With Modified Pancreaticojejunostomy
The aim of the present study was to observe whether the modified pancreatico- jejunostomy (PJ ) technique with an isolated pancreatic loop would effectively reduce the POPF rate and overall morbidity after PD
- Trial name
- NCT04843670
- Testing
- duodenopancreatectomy
- Volunteers
- 201 people
- Sponsor
- Université de Sousse
Pancreatic Cancer, Pancreaticoduodenal; Fistula
Early Detection of Anastomotic Leakage by Microdialysis Catheters
Anastomotic leakage of the pancreatojejunostomy is often discovered with considerable delay, causing severe peritonitis, hemorrhage due to erosion of vessels, sepsis, and death.
- Conditions
- Pancreatic Cancer, Pancreaticoduodenal; Fistula, Pancreas; Fistula, Pancreatic Fistula
- Trial name
- NCT03627559
- Testing
- Pancreaticoduodenectomy microdialysis catheter analyses
- Volunteers
- 35 people
- Sponsor
- Oslo University Hospital
Esophageal Neoplasms, Stomach Neoplasms
The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery
Improvements to treatment strategies for patients with cancers of the upper gastrointestinal tract have produced a large population of people who remain free from cancer recurrence in the long term following treatment.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02381249
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Pancreaticoduodenectomy
Three-Dimensional Vascular Reconstruction of the Pancreas on Multidetector Computed Tomography Images and Its Impact on Patients Undergoing Pancreaticoduodenectomy
Three-Dimensional Vascular Reconstruction of the Pancreas on Multi detector Computed Tomography images and its impact on patients undergoing Pancreatoduodenectomy - A Prospective Observational Study IPDA is difficult to identify…
- Trial name
- NCT05389917
- Testing
- Pancreaticoduodenectomy
- Volunteers
- 25 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Pancreatic Fistula
Risk Factors for Clinically Relevant Postoperative Pancreatic Fistula
For periampullary and pancreatic head disorders, pancreaticoduodenectomy (PD) is the standard treatment. However, PD is technically demanding and has high morbidity and mortality rates.
- Trial name
- NCT05687825
- Testing
- pancreaticoduodenectomy procedure
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- South Valley University
Intraoperative Care, Fluid Responsiveness
Short Time Low PEEP Challenge and Mini Fluid Challenge
Optimizing fluid therapy is one of the main concerns for anesthesiologists during the intraoperative period. It becomes even more important in high-risk long lasting surgeries as pancreaticoduodenectomy.
- Trial name
- NCT05419570
- Testing
- Fluid Loading
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul Saglik Bilimleri University