Clinical trials: Pandemic, COVID-19
COVID-19 Pandemic
A Phase 1, Randomised, Double-blinded, Placebo-controlled, Dose-escalation Study to Evaluate the Safety and Immunogenicity of RH109 as Booster
This is a randomized, double-blinded, placebo-controlled, dose-escalation study to valuate the safety and immunogenicity of RH109 as booster at 2 dose levels for ealthy adults who have received homologous or heterologous…
- Trial name
- NCT05609045
- Testing
- Lyophilized COVID-19 mRNA Vaccine, Sodium chloride
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wuhan Rhegen Biotechnology Co., Ltd.
Covid-19
Experimental Use of Convalescent Plasma for Passive Immunization in Current COVID-19 Pandemic in Pakistan in 2020
Experimental Use of Convalescent Plasma of Passive Immunisation In Current COVID-19 Pandemic in Pakistan in 2020 Rationale \& Objective: This study would help to gather real-life setting clinical data in local population…
- Trial name
- NCT04352751
- Testing
- convalescent plasma
- Where
- Pakistan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hilton Pharma
Adenomatous Polyps
Managing Colorectal Cancer Prevention Procedure Wait Lists During the COVID-19 Pandemic
The main objective of this study is to offer and evaluate an interim triage approach for patients waiting for surveillance colonoscopies.
- Trial name
- NCT04964596
- Testing
- colonoscopy, FIT test, CT colonography
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pregnancy Complications, Birth Injuries
SMS Maama Project COVID-19
The study's purpose is to demonstrate the ability of an mHealth platform as a feasible way of sharing information in a time of restricted movement in order to inform future studies.
- Trial name
- NCT04739462
- Testing
- mHealth Platform
- Where
- 2 sites in United States, Uganda
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
SARS-CoV-2 Infection
COVID MED Trial - Comparison Of Therapeutics for Hospitalized Patients Infected With COVID-19
In a randomized, double-blind, placebo-controlled, multi-center, Phase 2-like, investigator-directed trial, hospitalized adult patients with laboratory confirmed SARS-CoV-2 infection meeting inclusion and exclusion criteria, will…
- Trial name
- COVIDMED (NCT04328012)
- Testing
- Losartan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Bassett Healthcare
2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection
LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)
This master protocol serves as a common reference for the inpatient and outpatient clinical studies that share common elements.
- Conditions
- 2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection, 2019-nCoV Disease, 2019-nCoV Infection
- Trial name
- NCT05077332
- Testing
- Famotidine, Celecoxib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Leidos Life Sciences
Mental Health Wellness 1, Coaching
PanDirect: Self-care Tools and Telephone Coaching for Depression and Anxiety During Pandemics
During pandemics older adults with chronic physical conditions are a particularly vulnerable population for unmet mental health needs.
- Conditions
- Mental Health Wellness 1, Coaching, Pandemic, Depression, Anxiety
- Trial name
- NCT04609371
- Testing
- self-care tools, lay telephone coaching
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- St. Mary's Research Center, Canada
Stress, COVID-19
Social Workers of Elderly Care in Hungary
In our Research the goal is to examine the level of stress and burnout among social care workers and their causes and effects after COVID-19 pandemic.
- Conditions
- Stress, COVID-19, Burnout, Professional
- Trial name
- NCT05487157
- Where
- Hungary
- Volunteers
- 600 people
- Sponsor
- University of Pecs
COVID-19 Pneumonia
Covid-19 Pandemic and Use of Video Laryngoscopy
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a highly contagious infection with the highest viral load in the upper respiratory secretions.
- Trial name
- NCT05121701
- Testing
- Videolaryngoscope, Macintosh Laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Van Bölge Eğitim ve Araştırma Hastanesi
COVID-19 Infection, Melanoma
Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
The primary purpose of this study is to gain an understanding of how experiences during the COVID-19 pandemic, regardless of COVID-19 status, may have impacted multiple domains of health-related quality of life and other areas…
- Trial name
- NCT04474301
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 1,152 people
- Sponsor
- M.D. Anderson Cancer Center
In-hospital Mortality, Non-COVID Deaths
Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals
This study aims to perform a retrospective cohort study of administrative health data to understand how care delivery performance varies across US hospitals post-COVID-19 pandemic compared to the pre-pandemic performance.
- Conditions
- In-hospital Mortality, Non-COVID Deaths, Surge
- Trial name
- NCT06651645
- Testing
- COVID-19 Surge
- Where
- United States
- Volunteers
- 30,000,000 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Critical Illness, Family
Psychosocial Outcomes in Families of COVID-19 ICU Patients
During the first part of the SRAS-COV2 pandemic, families were not allowed to visit the patients in ICU. We know that families can develop "Family-PICS" after their relatives' ICU stay.
- Conditions
- Critical Illness, Family, Psychological Stress, Covid19
- Trial name
- NCT04498507
- Testing
- HADS questionnaire
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Liege
Psychological Distress
RESPOND: Improving the Preparedness of Health Systems to Reduce Mental Health and Psychosocial Concerns Resulting From the COVID-19 Pandemic
This randomized controlled trial will evaluate the implementation and (cost-)effectiveness of the culturally and contextually adapted Doing What Matters in times of stress (DWM) and Problem Management Plus (PM+) stepped-care…
- Trial name
- RESPOND (NCT04993534)
- Testing
- Stepped-care DWM/PM+, Psychological First Aid + usual care (CAU)
- Where
- Italy
- Volunteers
- 212 people
- Sponsor
- Universita di Verona
COVID-19 Infection
Assessment of the Psychosocial Impact of the COVID-19 Pandemic on the MD Anderson Cancer Center Workforce
This study investigates the impact of the COVID-19 pandemic on the psychosocial health of employees of MD Anderson Cancer Center.
- Trial name
- NCT04491292
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- M.D. Anderson Cancer Center
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Comparative Effectiveness of Telemedicine in Primary Care
Leveraging a natural experiment approach, the investigators will examine rapidly changing telemedicine and in-person models of care during and after the COVID-19 crisis to determine whether certain patients could safely choose to…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, Diabetes
- Trial name
- NCT04684836
- Testing
- Exposure to telemedicine, after the onset of the pandemic
- Where
- 4 sites in United States
- Volunteers
- 33,100 people
- Sponsor
- Weill Medical College of Cornell University
Covid19
Impact of Vitamin D Level and Supplement on SLE Patients During COVID-19 Pandemic
Aim of the work Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of…
- Trial name
- NCT04709744
- Testing
- Vitamin D, ELISA
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Older Adults
The Effectiveness of Health Promotion Programs on the Pre-frail Individuals
This pilot study aimed to examine the efficacy of a home-based multicomponent exercise training program in older community- dwellers during to the Coronavirus Disease 2019.
- Trial name
- NCT05476471
- Testing
- multicomponent exercise training program
- Where
- Taiwan
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Shu-Hung Chang
Syphilis, COVID - 19
Impact of Covid-19 on Syphilis
Sexually transmitted infections (STIs) represent a significant challenge to global public health. Although many of these infections are treatable, failure to diagnose and delayed treatment can lead to serious complications…
- Conditions
- Syphilis, COVID - 19, HIV (Human Immunodeficiency Virus), Retrospective Studies
- Trial name
- SIPAND (NCT07150871)
- Testing
- Patients diagnosed with syphilis
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Wilson's Disease and COVID-19
Impact of the Lockdown Due to the COVID Pandemic in French Wilson's Disease Patients
Wilson's disease is a rare genetic disorder that causes copper to build up in the body. This overload is initially localized in the liver and the brain, but can spread throughout the body and cause systemic damage if copper…
- Trial name
- WILL-Ecco (NCT05004701)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cancer
Oncology-patient-reported Anxiety, Mood, and QoL During the COVID-19 Pandemic
ONCOVID is a prospective cohort study investigating oncology-patient-reported anxiety, mood, and quality of life during the COVID-19 pandemic.
- Trial name
- ONCOVID (NCT04340219)
- Testing
- Survey administration
- Where
- Belgium
- Volunteers
- 394 people
- Sponsor
- University Hospital, Ghent
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