Clinical trials: Pandemic, COVID-19
Intrusive Memories of Traumatic Event(s)
A Brief GAmeplay Intervention for NHS ICU Staff Affected by COVID-19 Trauma (GAINS Study)
Intensive care unit (ICU) staff are frequently exposed to traumatic events at work (e.g., witnessing patients die), amplified by the COVID-19 pandemic.
- Trial name
- GAINS (NCT04992390)
- Testing
- Brief digital imagery-competing task intervention
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- P1vital Products Limited
COVID-19 Pandemic
Safety, Reactogenicity, and Immunogenicity Study of a Lyophilized COVID-19 mRNA Vaccine
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen that causes a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19), which is spreading all over the world.
- Trial name
- NCT05366296
- Testing
- A Lyophilized COVID-19 mRNA Vaccine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wuhan Recogen Biotechnology Co., Ltd.
Childhood Obesity, Sleep Problems
Evaluation of Innovative School-based Interventions on Health Outcomes Among Primary School Students During Post COVID-19 Pandemic
Objectives: (1) to evaluate the feasibility of innovative school-based interventions on health outcomes (psychological well-being, depressive symptoms, anxiety symptoms, physical activity, sleep duration, and sleep quality) among…
- Conditions
- Childhood Obesity, Sleep Problems, Physical Activity
- Trial name
- WeJoy+WeHop (NCT06766890)
- Testing
- WeJoy+WeHop
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Burnout
Burn-out Among Chinese Anaesthesiologist After COVID-19 Pandemic Peak and Its Protective Factor： a National Survey
The investigators proposed a national representative survey to collect data of socio-demographic characteristics, level of exposure to COVID-19, depression，anxiety， ptsd， burnout and resilience of working anaesthesiologists…
- Trial name
- NCT04967820
- Testing
- resilience and institutional support
- Where
- China
- Volunteers
- 6,631 people, healthy volunteers welcome
- Sponsor
- Huang YuGuang
Covid-19
Evaluation of the Evolution of Pregnancies in the First Trimester Following MAR Management During a COVD-19 Pandemic Period
Because of the physiological changes inherent in pregnancy, pregnant women with lower respiratory tract infections often have more worrisome outcomes compared to non-pregnant individuals, including a higher rate of hospital and…
- Trial name
- AMPCOVID-19 (NCT04415359)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiac Surgery
Prophylactic Effect of Nirmatrelvir/Ritonavir and Ursodeoxycholic Acid on Reducing Complications After Cardiac Surgery
Prophylactic effect of nirmatrelvir/ritonavir and ursodeoxycholic acid on reducing complications after cardiac surgery during covid-19 pandemics (the pep trial) is a multicenter, randomized controlled trial.
- Trial name
- PEP (NCT05690646)
- Testing
- Nirmatrelvir/ritonavir, Ursodeoxycholic acid
- Where
- China
- Volunteers
- 491 people
- Sponsor
- China National Center for Cardiovascular Diseases
Quality of Life
QUALITATIVE SURVEY ABOUT NURSES FIRST WORK EXPERIENCE DURING COVID-19 PANDEMIC
During covid-19 pandemic an huge reorganization of all PiacenzaHospital was done to manage the increasing requests for hosptitalization. New nurses had to face first work experience in full pandemic Emergency.
- Trial name
- NCT05110859
- Testing
- in-depth individual interviews
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
COVID-19, Non-specific Effects of Vaccines
Using BCG Vaccine to Protect Health Care Workers in the COVID-19 Pandemic
Background: The COVID-19 pandemic challenges the available hospital capacity, and this will be augmented by absenteeism of healthcare workers (HCW).
- Conditions
- COVID-19, Non-specific Effects of Vaccines, Morbidity, Absenteeism
- Trial name
- NCT04373291
- Testing
- BCG-Denmark, Saline
- Where
- Denmark
- Volunteers
- 1,293 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
COVID-19 Infections, Respiratory Infections, Acute
Volatile Organic Compounds Analysis by PTR-TOF-MS for Screening Respiratory Infections Using Exhaled Breath.
Emerging respiratory diseases are a global health threat. Viruses such as influenza and coronaviruses have been the main cause of pandemics over the last century.
- Trial name
- VORTEX 1 (NCT07348380)
- Testing
- Volatile Organic compounds (VOC) analysis in Exhaled breath using PTR-TOF-MS
- Where
- 3 sites in France
- Volunteers
- 1,665 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Parkinson Disease, Covid19
Parkinson's Disease and Experiences Throughout the COVID-19 Pandemic
The purpose of this research study is to examine the relationship between personal characteristics and satisfaction with care in those diagnosed with Parkinson's disease during the COVID-19 pandemic.
- Conditions
- Parkinson Disease, Covid19, Satisfaction, Patient, Quality of Life
- Trial name
- NCT04720118
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Towson University
Anxiety, COVID-19 Pandemic
SMILE: Clinical Trial to Evaluate Mindfulness as Intervention for Racial and Ethnic Populations During COVID-19
The goal of this clinical trial is to evaluate the SMILE app, a Digital Health Platform (DHP), that will deliver a mindfulness intervention, designed to mitigate COVID-19 related stress.
- Trial name
- SMILE (NCT06242080)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of North Carolina, Chapel Hill
Mental Health Disorder
CoCo-20: a Longitudinal Follow-up Study of the French Paediatric Population During and After the Coronavirus Pandemic COVID-19
In the context of a viral outbreak and of widespread quarantine measures, a significant increase in psychological disorders, such as stress or fear behaviours, had previously been observed.
- Trial name
- CoCo-20 (NCT04498416)
- Testing
- Quantitative and qualitative assessments of mental health
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Fondation Lenval
COVID-19 Pandemic
Elevated Liver Enzymes as a Predictor of Acute Kidney Injury in Hospitalized Patients With COVID-19
In critically ill patients, AKI is a common complication of COVID-19 infection, occurring in 23% to 43% of cases, and was correlated with poor clinical outcomes.
- Trial name
- COVID-19 (NCT05157152)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Coping Skills, Anxiety
The Effect of the Emotional Freedom Technique on Students
Introduction: The interruption of education within the scope of quarantine and isolation methods during the pandemic process has caused nursing students studying in clinical practice areas to be away from the clinic for a long…
- Conditions
- Coping Skills, Anxiety, Complementary Therapies, Stress
- Trial name
- NCT05227560
- Testing
- Complementary Therapies
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
COVID-19
Educational Interventions for Surgeons During COVID-19 Pandemic: Cross-sectional, E-survey
The coronavirus disease 2019 (COVID-19) pandemic required a rapid surge of healthcare capacity to face a growing number of critically ill patients.
- Trial name
- EDUCOVID (NCT04732858)
- Testing
- Cross sectional e-Survey on surgeons exposed to any educational intervention
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Invasive Group A Beta-Haemolytic Streptococcal Disease
Severe Group A Streptococcus Infections in Paris, France, 2018-2023
Streptococcus pyogenes, commonly referred to as Group A Streptococcus (GAS), has the ability to induce a diverse range of illnesses.
- Trial name
- IGASI (NCT06297122)
- Testing
- Collection of data from the patient's medical file
- Where
- France
- Volunteers
- 269 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression Symptoms, Anxiety Symptoms
ICBT for Psychological Symptoms Related to the COVID-19 Pandemic Remaining After Societal Opening
This study aim to investigate the effects of internet-based cognitive behavioral therapy (ICBT) addressing psychological symptoms related to the COVID-19 pandemic and its consequences that remain after societal opening.
- Trial name
- PCC (NCT05656430)
- Testing
- Internet-based Cognitive Behavioral Therapy
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Linkoeping University
No-Show Patients, Therapeutic Adherence and Compliance
Evaluation of the Relationship Between Missed Appointments and Adherence to Medical Indications
We will conduct a cross-sectional study involving adults with type 2 diabetes mellitus. Our primary objective is to evaluate the association between nonattendance and participants' adherence to both pharmacological and…
- Conditions
- No-Show Patients, Therapeutic Adherence and Compliance, Type 2 Diabetes Mellitus, COVID-19
- Trial name
- NCT06501456
- Where
- Argentina
- Volunteers
- 46 people
- Sponsor
- Hospital Italiano de Buenos Aires
Conjunctivitis, SARS-CoV-2
Prevalence of SARS-CoV-2 in Conjunctival Swab Samples Among Patients With Conjunctivitis During the COVID-19 Pandemic
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly identified, highly contagious RNA virus causing respiratory infectious disease, Coronavirus Disease 2019 (COVID-19).
- Conditions
- Conjunctivitis, SARS-CoV-2, COVID-19, Ocular Infection, Viral
- Trial name
- NCT04374656
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
TB - Tuberculosis, Patient Satisfaction
To Assess the Efficiency and Satisfaction of Pharmacist Giving Patient-centred Advice on Telephone Consultation in TB Patients: Experience of the COVID-19 Pandemic
The COVID-19 pandemic might be an opportunity to review and refine our practices in anti TB treatment. For the follow-up of selected patients, telephone consultations may be efficient and cost-effective.
- Trial name
- Coronavirus19 (NCT04412239)
- Testing
- Patient-centred advice on Telephone Consultation in TB Patients:
- Where
- 2 sites in Pakistan
- Volunteers
- 200 people
- Sponsor
- Xi'an Jiaotong University
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