Clinical trials: Pandemic, COVID-19
Gallstone
Impact of COVID-19 Pandemic on Single-stage Laparoscopic Cholecystectomy and Laparoscopic Common Bile Duct Exploration Service
Choledocholithiasis is reported to be present in 15-20% of patients with symptomatic gallstones. The single-stage management consists of performing either laparoscopic common bile duct exploration (LCBDE) or intraoperative…
- Trial name
- NCT06974045
- Testing
- Single-stage LC + LCBDE
- Volunteers
- 237 people
- Sponsor
- Imperial College London
Long COVID, COVID-19 Pandemic
Long COVID and Its Associations With Health Outcomes in Older Adults
The Peking University Health Cohort in Anning, Yunnan (PKUHC-AN) is a prospective cohort study carried out in Anning, Yunnan. The primary aim of this study is to investigate the impact of COVID-19 on older adults' health, and to…
- Conditions
- Long COVID, COVID-19 Pandemic, Elderly Infection, Vaccine Reaction
- Trial name
- NCT05825651
- Testing
- no interventions
- Where
- China
- Volunteers
- 11,527 people, healthy volunteers welcome
- Sponsor
- Peking University
Stress, Anxiety
Emotional Freedom Technique (EFT) Effect on Nurses
Background: Infectious disease outbreaks have a psychological effect on the general population, and especially on health workers.
- Conditions
- Stress, Anxiety, Burnout, Caregiver
- Trial name
- NCT04393077
- Testing
- Emotional Freedom Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Child Mental Health
Child and Adolescent Mental Health Literacy for Primary Schools Teachers. A Multicomponent Intervention
Child mental health (CMH) is crucial for lifelong well-being. Early prevention and intervention are vital for public health, yet Chile faces a high prevalence of CMH issues, particularly in children aged 4 to 11.
- Trial name
- NCT06121739
- Testing
- Child Mental Health Literacy Program
- Where
- Chile
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Critically Illness, Sedation
Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19)
The authors hypothesized that inhaled sedation, either with isoflurane or sevoflurane, might be associated with improved clinical outcomes in patients with COVID-19-related ARDS, compared to intravenous sedation.
- Conditions
- Critically Illness, Sedation, Invasive Mechanical Ventilation, Acute Respiratory Distress Syndrome
- Trial name
- ISCA (NCT04383730)
- Testing
- Intravenous sedation, Inhaled sedation
- Where
- 12 sites in United States, France and 3 more
- Volunteers
- 203 people
- Sponsor
- University Hospital, Clermont-Ferrand
COVID-19 Pandemic, COVID-19 Vaccines
UNAIR Inactivated COVID-19 Vaccine as Heterologue Booster (Immunobridging Study)
This is an observer blind randomized controlled trial study to evaluate the humoral immunogenicity profile - neutralizing antibody - after 28 days following vaccination with Vaksin Merah Putih - UA SARS-CoV-2 (Vero Cell…
- Trial name
- NCT05918939
- Testing
- Vaksin Merah Putih - UA SARS-CoV-2 (Vero Cell Inactivated) 5 µg, CoronaVac Biofarma COVID-1 9 Vaccine 3 µg
- Where
- Indonesia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Acute Appendicitis
MANAGEMENT OF APPENDICITIS DURING THE COVID-19 PANDEMIC
During the Covid-19 pandemic, non-operative management for acute appendicitis (AA) was implemented in the UK. The aim of this study was to determine the efficacy and outcomes of conservative versus surgical management of AA…
- Trial name
- observational (NCT04615728)
- Testing
- laparoscopic or open appendicectomy
- Where
- United Kingdom
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Corneal Wavefront Aberration, SARS-CoV-2
Changes of Optical Quality During the Peak of the Covid-19 Pandemic
To explore whether cornea structure, and optical quality are affected by the covid-19 infection.
- Trial name
- NCT05882383
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Covid19
Sex-Informed Data in the COVID-19 Pandemic.
Sex and gender matter to health equity, especially in a pandemic. Sex (a biological attribute) and gender (a social construct) may influence an individual's susceptibility, vulnerability and exposure to infectious disease.
- Trial name
- G-COV (NCT04497402)
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Anxiety, Depression
Difficulties in Emotion-regulation and Interpersonal Problems During and After the COVID-19 Pandemic
Central indicators of psychological functioning such as difficulties in emotion regulation and habitual problems in one's relating to others are likely to have been substantially impacted by the COVID-19 amelioration measures of…
- Conditions
- Anxiety, Depression, Interpersonal Problem, Emotion Regulation
- Trial name
- NCT04442282
- Volunteers
- 5,041 people
- Sponsor
- University of Oslo
HIV Infections
Vaccines in a Time of Dual Pandemic: COVID-19 Vaccine in People With HIV
This is a prospective, non-randomized observational study to examine SARS-CoV-2 vaccine immunogenicity, immune activation and HIV reservoirs in people with HIV infection in comparison with HIV-negative individuals, in those aged…
- Trial name
- NCT06731127
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Burnout, Stress, Emotional
Effect of Positive Attitudes on Behavior and Wellness
The COVID-19 pandemic has undoubtedly elevated levels of stress to people all over the globe, but none more than to the providers on the front-line.
- Trial name
- TEAM-ICU (NCT04441632)
- Testing
- Positive feedback
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
HIV Infections, Syphilis
Impact of COVID-19 on Provision and Uptake of Prevention of Mother-to-child Transmission of HIV Services in Zimbabwe
The COVID-19 pandemic and response are likely to lead to severe unintended consequences for the prevention of mother-to-child transmission (PMTCT) of HIV and syphilis.
- Trial name
- NCT04782739
- Testing
- None - Descriptive study
- Where
- 2 sites in Zimbabwe
- Volunteers
- 30 people
- Sponsor
- University of Zimbabwe
Covid19, Rheumatic Fever
Impact of COVID-19 Pandemic and Social Distancing on Mental Health of Chronic Inflammatory Rheumatism Affected Patients
Recent studies have highlighted the consequences of COVID-19 pandemic and social distancing on mental health of individuals. The aim of this study is to evaluate those consequences within a sample of inflammatory chronic…
- Conditions
- Covid19, Rheumatic Fever, Mental Disorder
- Trial name
- EMOPTION (NCT04798053)
- Testing
- Questionnaire, blood sample and salivary sample
- Where
- 7 sites in France
- Volunteers
- 259 people
- Sponsor
- University Hospital, Bordeaux
Mental Disorder, Child
Impact of the COVID-19 Pandemic on Mental Health Service Utilization in Children and Adolescents
Mental health consequences of the COVID-19 pandemic may be vast and may potentially overwhelm the mental health system in a long-lasting manner.
- Trial name
- MENTALPED (NCT05260866)
- Testing
- national population-based study
- Where
- France
- Volunteers
- 500,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Irritation/Irritant, ICD - Irritant Contact Dermatitis
The Effects of Repeated Exposure to Antiseptics During COVID-19 Pandemic on Skin Parameters
The global coronavirus disease pandemic (COVID-19) has led to an increased need to wear protective equipment such as wearing face masks and practicing hygiene measures such as more frequent use of antiseptics.
- Conditions
- Irritation/Irritant, ICD - Irritant Contact Dermatitis, Antiseptic
- Trial name
- NCT05276102
- Testing
- Emollient cream
- Where
- Croatia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
COVID-19, SARS-CoV-2 Infection
COVID-19 on Placental Gene Expression and Pathology
Little is known regarding the effect of antenatal COVID-19 on pregnancy outcomes. The purpose of this study is to determine of COVID-19 alters histopathology and gene expression of the placenta, as evidenced by analysis at time…
- Trial name
- PROSPER (NCT04585945)
- Testing
- Positive for SARS-CoV-2 infection
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Prisma Health-Upstate
Anosmia, Covid19
COVID-19 in Patients With Anosmia in Egypt
The study aims to test the frequency of severe acute respiratory syndrome new corona virus SARS-CoV-2 or other respiratory viruses in patients presenting with anosmia or dysgeusia to Ain Shams University Hospitals, Cairo, Egypt.
- Conditions
- Anosmia, Covid19, Dysgeusia
- Trial name
- NCT04473157
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Ain Shams University
Covid19
COVID-19 and Sports - an Online Survey on the Impact of the Pandemic and Possible Preventive Measures
Aim of the study was to investigate the effects of the COVID-19 pandemic on individual and general sport activities in an effort to provide information for safe return to community sports.
- Trial name
- NCT04649333
- Where
- Austria
- Volunteers
- 1,336 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Covid-19, Maternal Psychological Distress
Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anaesthetic Management.
The aim of this study is to assess the maternal psychological implication of the novel coronavirus COvid-19 pandemic. At the same time it will be evaluated whether there is an impact of these implications on the anaesthetic…
- Conditions
- Covid-19, Maternal Psychological Distress, Anesthesia
- Trial name
- NCT04432948
- Testing
- PHQ-9 Depression Scale, GAD-7 General anxiety disorder scale, 38-questions questionnaire
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- General and Maternity Hospital of Athens Elena Venizelou
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