Clinical trials: Pandemics, open to volunteers
COVID-19 Pneumonia, COVID-19 Pandemic
Corona Virus Disease 2019 Cohort Study
The goal of this observational study is to learn about the influence of Corona Virus Disease 2019 on obstetric outcome and offspring development.
- Conditions
- COVID-19 Pneumonia, COVID-19 Pandemic, COVID-19
- Trial name
- NCT06927622
- Where
- 5 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shandong University
COVID-19 Infections, Respiratory Infections, Acute
Volatile Organic Compounds Analysis by PTR-TOF-MS for Screening Respiratory Infections Using Exhaled Breath.
Emerging respiratory diseases are a global health threat. Viruses such as influenza and coronaviruses have been the main cause of pandemics over the last century.
- Trial name
- VORTEX 1 (NCT07348380)
- Testing
- Volatile Organic compounds (VOC) analysis in Exhaled breath using PTR-TOF-MS
- Where
- 3 sites in France
- Volunteers
- 1,665 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
DENV Without Warning Signs, DENV with Warning Signs
Innovative Multidisciplinary Strategies for Combating Severe Dengue
The goal of this observational study is to identify biomarkers and host factors associated with dengue severity in patients from dengue-endemic regions.
- Conditions
- DENV Without Warning Signs, DENV with Warning Signs, Severe Dengue, Healthy Controls Group - Age and Sex-matched
- Trial name
- COMBAT (NCT06751836)
- Testing
- Infection and no infection
- Where
- 2 sites in Guatemala, India
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Covid-19 Pandemics, Tuberculosis
Immunogenicity of COVID-19 Vaccines in Tuberculosis Patients
This study is a non-randomized observation and comparison of immune response between bacteriologically confirmed TB patients under treatment cohort who received COVID-19 vaccine (n=54) vs healthy individuals (n=54).
- Trial name
- CVTB (NCT05571735)
- Testing
- Pfizer-BioNTech COVID-19 vaccine, AstraZeneca vaccine, Janssen Ad26.COV2.S COVID-19 vaccine
- Where
- Thailand
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Oxford
COVID-19 Infection
Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The global outbreak of COVID-19 is a major public health problem. COVID-19 causes a wide range of symptoms.
- Trial name
- NCT04582903
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Patient Violence
Pain Clinic Staff Harassed by Patients Pre/Post COVID
Chronic pain may cause psychological or behavioral problems. Chronic pain patients occasionally harass the pain care providers. The COVID-19 pandemic caused major stress for the general population.
- Trial name
- NCT05938101
- Testing
- Behavioral therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Depressive Symptoms, Depression
Efficacy and Safety of Auricular Acupuncture in Depression During the Covid 19 Pandemic
Participants with moderate depressive symptoms measured by PHQ-9 will be randomized to receive auricular acupuncture. The triple blinded procedure will be conducted in 12 sessions (6 weeks).
- Conditions
- Depressive Symptoms, Depression, Anxiety, Insomnia
- Trial name
- NCT05855421
- Testing
- Auricular Acupuncture
- Where
- Brazil
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidade do Sul de Santa Catarina
Health Disparities, Food Security
The Effect of Work Requirements in SNAP in Virginia
More than a dozen states have proposed or plan to implement work requirements in Medicaid, and similar requirements already exist nationally in the Supplemental Nutritional Assistance Program (SNAP), yet evidence on the effects…
- Trial name
- NCT04888832
- Testing
- Work requirement exemption months
- Where
- United States
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Influenza (Healthy Volunteers)
Establishing a Controlled Human Infection Model for Influenza H3N2 as a Foundation for Pandemic Preparedness
The overall objective is to establish an influenza Controlled Human Infection Model (CHIM) in Canada that can be used to assess the safety and efficacy of candidate vaccines, biologics, and therapeutics targeting influenza…
- Trial name
- NCT07305207
- Testing
- Intranasal inoculation of RG-A/Texas/71/2017 (H3N2) influenza in each naris on Day 1 of the study.
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Teamwork
Teamwork for Resilient Staff and Safe Care in ICU
The goal of this ethnographic study is to observe how healthcare professionals work together in an intensive care unit (ICU). The main questions it aims to answer are How do healthcare staff work together in everyday ICU…
- Trial name
- FEARLESS_ICU (NCT06389773)
- Where
- 3 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King's College London
Alcohol Drinking, Alcohol-Related Disorders
COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study
Background: The SARS-CoV-2 virus has caused a pandemic infection called COVID-19. It is a global threat to people, communities, and health systems. Researchers are concerned about the mental health effects of the pandemic.
- Conditions
- Alcohol Drinking, Alcohol-Related Disorders, Pandemic, Psychological Stress
- Trial name
- NCT04391816
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Pneumococcal Carriage
Post Pandemic Pneumococcal Carriage Among Children and Adults
The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city.
- Trial name
- NCT06373328
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Respiratory Viruses
Surveillance of Respiratory Viruses in Healthcare and Animal Workers
Outbreaks with viruses occur continuously, and novel viruses or new variants of existing viruses can surface after a zoonotic event or human-to-human transmission.
- Trial name
- SENTINEL (NCT07156890)
- Where
- Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Physical Activity, Cardiorespiratory Fitness
Combating Physical Inactivity Pandemic in Kindergartens
The aim of this study is to examine the effects of a kindergarten-based, parent-involved intervention during the upper kindergarten year (K3) on physical activity and physical fitness in preschool children.
- Trial name
- NCT05521490
- Testing
- Usual Care Control, Physical Activity Enhanced Curriculum
- Where
- Hong Kong
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Social Support (Formal and Informal)
The Supporting Her In Navigating Exercise Program: Examining Peer Support to Promote Exercise Among Undergraduate Women
The purpose of this randomized controlled pilot trial is to test the effectiveness of a six-week tailored physical activity program with and without peer mentoring on the psychological constructs and exercise behaviour of…
- Trial name
- SHINE (NCT06823336)
- Testing
- Intervention, Control
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Influenza Prevention, Pandemic Influenza Prevention
Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy Adults
Background: Influenza (flu) is a contagious respiratory illness caused by viruses. Flu symptoms can range from mild to severe, and the illness can be fatal. Vaccines help the body learn to prevent or fight infections such as flu.
- Trial name
- NCT07111078
- Testing
- VRC-FLUMOS0122-00-VP, ALFQ
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19 Pandemic, Professional Stress
Mental Health of Professionals of the Silver Economy of New Aquitaine : Online Survey of Accommodation Establishments for Old People and Home Assistance Establishments
The purpose of this study is identify the psychological impact of the coronavirus-19 pandemic on professionals in residential care facilities for old people and home help professionals in New-Aquitaine by : 1.
- Trial name
- SILVER NA (NCT05381883)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Mental Health
Cocreation and Evaluation of an Escape Game on Students' Mental Health
The Covid-19 pandemic and the protracted lockdowns have heavily impacted university students' mental health. Digital Escape Games represent a good means to reach students and propose them solutions for their psychological…
- Trial name
- EscapeCovid (NCT06720792)
- Testing
- EscapeCovid
- Where
- France
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Motivational Factors for Nurse Retention, Nurse Well-being
Health System Methods to Improve Nursing Retention Amidst Ongoing COVID-19 Pandemic: a Mixed Method Study
This study is a mixed-method exploratory study with the aim to determine an objective compensation or mechanism of support from a healthcare system standpoint to aid in retention of nursing staff amidst the ongoing COVID-19…
- Trial name
- NCT05269277
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poudre Valley Health System