Clinical trials: Panic
Alcoholism, Generalized Anxiety Disorder
Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
The purpose of this study is to determine if levetiracetam is effective in treating alcohol dependence in patients with anxiety symptoms.
- Conditions
- Alcoholism, Generalized Anxiety Disorder, Panic Disorder, Social Phobia
- Trial name
- NCT00141115
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- New York State Psychiatric Institute
Panic Disorder
A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients
The primary objective of this study is to test the hypothesis that a SSRI plus quetiapine SR (Seroquel SR) will result in superior early (first 1-3 weeks of treatment) stabilization of panic symptoms in SSRI-resistant, comorbid…
- Trial name
- NCT00619892
- Testing
- quetiapine XR
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Indiana University
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training
This study seeks to understand emotion regulation in those with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06132659
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Michigan
Cancer
Relaxation and Heart Rate Variability
Primary: To characterize the physiologic changes of the autonomic nervous system, demonstrated by heart rate variability (HRV) high frequency (HF) spectral analysis, before and after a 15 minute, one-time, guided relaxation…
- Trial name
- NCT00735618
- Testing
- Guided Relaxation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Anxiety
Youth Mayo Clinic Anxiety Coach Pilot Study
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205177
- Testing
- Mayo Clinic Anxiety Coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stephen Whiteside
Panic Disorder, Major Depressive Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major Depression
This study will evaluate the efficacy of 1-Hz rTMS applied to the right Dorsolateral Prefrontal Cortex (DLPFC) in patients with Panic Disorder (PD) and comorbid Major Depressive Disorder (MDD) who have not fully responded to…
- Trial name
- rTMS (NCT00521352)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New York State Psychiatric Institute
Panic Disorder
Safety and Efficacy of HB-1 for Panic Disorder
The purpose of this study is to determine the safety and efficacy of potential new treatment called "HB-1" versus placebo in male and female adult patients aged 18 to 60 years, inclusive, with panic disorder.
- Trial name
- NCT05071430
- Testing
- HB-01
- Where
- 10 sites in United States
- Volunteers
- 86 people
- Sponsor
- HB BioTech, LLC
Depression, Anxiety
Efficacy and Feasibility of a Personalized Treatment for Depression With Co-Occurring Anxiety
This study will examine the feasibility and efficacy of a personalized psychotherapy treatment for people with depression and co-occurring anxiety.
- Trial name
- NCT00930293
- Testing
- Interpersonal Psychotherapy for Depression with Panic and Anxiety Symptoms (IPT-PS), Brief Supportive Psychotherapy (BSP), Citalopram hydrobromide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Bipolar Disorder, Panic Disorder
Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of quetiapine SR monotherapy and divalproex sodium ER monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT00579280
- Testing
- quetiapine SR, divalproex sodium ER
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Healthy
A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms
The main objective of this trial is to investigate the pharmacodynamic effects of a single dose of BI 1358894 on CCK-4- induced anxiogenic/ panic-like symptoms using the PSS in preselected CCK-4 sensitive healthy volunteers.
- Trial name
- NCT03904576
- Testing
- BI 1358894
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Panic Disorder
A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic Disorder
To evaluate the efficacy and safety of sertraline compared to paroxetine in patients with panic disorder.
- Trial name
- NCT00677352
- Testing
- sertraline, Paroxetine
- Where
- 22 sites in Japan
- Volunteers
- 321 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
PTSD, Panic Attacks
Exposure Therapy For Veterans With PTSD And Panic Attacks
To evaluate the feasibility, acceptability and effectiveness of Multiple Channel Exposure Therapy-Veterans (MCET-V) as a treatment for returning service members with comorbid PTSD and panic disorder (PD).
- Trial name
- NCT01033136
- Testing
- Multiple Channel Exposure Therapy - Veterans, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- VA Office of Research and Development
Anxiety
A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care
This 4-year study will examine the value of a type of a brief cognitive behavioral therapy treatment for Veterans with anxiety and worry.
- Trial name
- NCT04523779
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Asthma, Panic Disorder
LUCHAR - Latinos Using Counseling for Help With Asthma and Anxiety Reduction
The research plan involves two aims: 1) Cultural adaptation of the Panic-Asthma Treatment and 2) a randomized, placebo-controlled pilot study.
- Trial name
- LUCHAR (NCT01583296)
- Testing
- Music Relaxation Therapy (MRT), CBT and HRVB
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Albert Einstein College of Medicine
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorder, Panic Disorder
Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of ziprasidone monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with co-morbid lifetime panic disorder or…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- PfizerAnxty (NCT01172652)
- Testing
- Ziprasidone
- Where
- 3 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Panic Disorder
The Efficacy and Tolerability of Duloxetine for the Treatment of Panic Disorder
The purpose of this study is to determine whether duloxetine is effective in the treatment of panic disorder.
- Trial name
- NCT00438971
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Treatment of Induced Panic Attack
Staccato Alprazolam in Panic Attack
We are developing Staccato™ Alprazolam for the treatment of Panic attacks associated with panic disorder. This study will provide an initial assessment of efficacy, and to continue to describe the tolerability and…
- Trial name
- NCT00477451
- Testing
- Inhaled alprazolam 1 mg, Inhaled alprazolam 2 mg, IV doxapram
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alexza Pharmaceuticals, Inc.
Anxiety Disorder
Adjunctive Family CBT for Veterans With Anxiety
Despite the prevalence of posttraumatic stress disorder and anxiety disorders among Veterans, there has been limited focus on the development of interventions that include family members in treatments provided to Veterans.
- Trial name
- AF-CBT (NCT05340478)
- Testing
- Adjunctive Family - Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Panic Disorder
A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder
The purpose of this trial is to measure the efficacy, safety, and tolerability of darigabat (25 milligrams [mg] twice daily [BID]) compared with placebo in participants with panic disorder.
- Trial name
- NCT05941442
- Testing
- Darigabat
- Where
- 31 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie