Clinical trials: Panic Disorder
Nicotine Addiction, Panic Attack
Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine
The purpose of the current study is to evaluate the efficacy of d-cycloserine in augmenting treatment of smoking cessation for individuals with panic attacks.
- Trial name
- DCS/PSRT (NCT01944423)
- Testing
- d-cycloserine, Nicotine replacement therapy, Panic and Smoking Reduction Treatment
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Panic Disorder
A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients
The primary objective of this study is to test the hypothesis that a SSRI plus quetiapine SR (Seroquel SR) will result in superior early (first 1-3 weeks of treatment) stabilization of panic symptoms in SSRI-resistant, comorbid…
- Trial name
- NCT00619892
- Testing
- quetiapine XR
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Indiana University
Panic Disorder, Insomnia
Ramelteon for Sleep Initiation Insomnia in Individuals With Panic Disorder Who Are Also on Escitalopram for Anxiety
Almost 80% of panic disorder patients report difficulty sleeping. Sleep disturbances in turn may exacerbate underlying anxiety/panic attacks.
- Trial name
- NCT00746239
- Testing
- Ramelteon and Escitalopram
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Milton S. Hershey Medical Center
Major Depressive Disorder, Persistent Depressive Disorder
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and anxiety disorders.
- Conditions
- Major Depressive Disorder, Persistent Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder
- Trial name
- TBT-RCT (NCT01947647)
- Testing
- Transdiagnostic Behavior Therapy, Behavioral Activation Therapy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Bipolar Disorder, Panic Disorder
Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of ziprasidone monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with co-morbid lifetime panic disorder or…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- PfizerAnxty (NCT01172652)
- Testing
- Ziprasidone
- Where
- 3 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Anxiety
A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care
This 4-year study will examine the value of a type of a brief cognitive behavioral therapy treatment for Veterans with anxiety and worry.
- Trial name
- NCT04523779
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Anxiety Disorder
Adjunctive Family CBT for Veterans With Anxiety
Despite the prevalence of posttraumatic stress disorder and anxiety disorders among Veterans, there has been limited focus on the development of interventions that include family members in treatments provided to Veterans.
- Trial name
- AF-CBT (NCT05340478)
- Testing
- Adjunctive Family - Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Panic Disorder
A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder
The purpose of this trial is to measure the efficacy, safety, and tolerability of darigabat (25 milligrams [mg] twice daily [BID]) compared with placebo in participants with panic disorder.
- Trial name
- NCT05941442
- Testing
- Darigabat
- Where
- 31 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie
Panic Disorder
Exposure, D-Cycloserine Enhancement, and Genetic Modulators in Panic Disorder
This is a 5-year double blind, randomized, controlled, trial conducted at three treatment sites, aimed at showing the acute and longer-term effects of DCS augmentation of exposure-based CBT for panic disorder relative to placebo…
- Trial name
- DCSPanic (NCT00790868)
- Testing
- d-cycloserine
- Where
- 4 sites in United States
- Volunteers
- 180 people
- Sponsor
- Boston University Charles River Campus
Panic Disorder
Efficacy of Aerobic Exercise Added to Alprazolam in Panic Disorder Treatment
The purpose of this study is to determine whether the combination of aerobic physical exercise and alprazolam in patients with panic disorder has a better therapeutic response than the treatment with alprazolam alone.
- Trial name
- AEIPDT (NCT00803400)
- Testing
- Alprazolam, Alprazolam + Aerobic exercise
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- University of Buenos Aires
Bipolar Disorder, Panic Disorder
Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of quetiapine SR monotherapy and divalproex sodium ER monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT00579280
- Testing
- quetiapine SR, divalproex sodium ER
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of South Florida
PTSD, Panic Attacks
Exposure Therapy for Veterans With PTSD and Panic Attacks (Phase 1)
To evaluate the feasibility, acceptability and effectiveness of Multiple Channel Exposure Therapy-Veterans (MCET-V) as a treatment for returning service members with comorbid posttraumatic stress disorder (PTSD) and panic…
- Trial name
- NCT01551199
- Testing
- Multiple Channel Exposure Therapy- Veterans
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Asthma, Panic Disorder
LUCHAR - Latinos Using Counseling for Help With Asthma and Anxiety Reduction
The research plan involves two aims: 1) Cultural adaptation of the Panic-Asthma Treatment and 2) a randomized, placebo-controlled pilot study.
- Trial name
- LUCHAR (NCT01583296)
- Testing
- Music Relaxation Therapy (MRT), CBT and HRVB
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Albert Einstein College of Medicine
Anxiety Disorders, Panic Disorder
Comparison of Psychotherapy Programs to Treat Panic Disorder
This study will determine the relative effectiveness of three psychotherapies in treating people with a panic disorder.
- Conditions
- Anxiety Disorders, Panic Disorder, Agoraphobia
- Trial name
- NCT00353470
- Testing
- Cognitive behavioral therapy, Applied relaxation training (ART), Panic focused psychodynamic psychotherapy (PFPP)
- Where
- 2 sites in United States
- Volunteers
- 201 people
- Sponsor
- Weill Medical College of Cornell University
Panic Disorder
The Role of Orexin in Human Panic Disorder
The purpose of this study is to provide some information (pilot data) about whether the study drug, suvorexant, (1) affects levels of orexin in people with panic disorder, and (2) is associated with decreased panic symptoms in…
- Trial name
- NCT02593682
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, San Francisco
Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions…
- Conditions
- Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety
- Trial name
- NCT04922502
- Testing
- Standard SPACE, Bibliotherapy, low therapist contact SPACE
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Major Depressive Disorder, Posttraumatic Stress Disorder
Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective treatment for individuals with depressive/anxiety disorders.
- Conditions
- Major Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder and Agoraphobia
- Trial name
- NCT04293341
- Testing
- Transdiagnostic Behavior Therapy, Cognitive Processing Therapy for PTSD, Cognitive Behavioral Therapy for MDD
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- VA Office of Research and Development
Depression, Generalized Anxiety Disorder
A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients
For this trial, the investigators propose a prospective trial of a collaborative care program to identify and treat depression, generalized anxiety disorder, and panic disorder among patients admitted to the hospital for an acute…
- Conditions
- Depression, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- MOSAIC (NCT01201967)
- Testing
- Collaborative care, Usual care
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Massachusetts General Hospital
Generalized Anxiety Disorder, Panic Disorder
Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSRI or SNRI to Treatment With an SSRI or SNRI Alone in Subjects With Generalized Anxiety Disorder or Panic Disorder
An 8-week, open-label trial in 848 subjects at 212 sites to compare time to response in symptoms of anxiety in subjects treated with Niravam™ and a newly prescribed Selective Serotonin Reuptake Inhibitor (SSRI)or Serotonin and…
- Trial name
- NCT00266409
- Testing
- Niravam, SSRI/SNRI
- Where
- United States
- Volunteers
- 418 people
- Sponsor
- UCB Pharma