Clinical trials: Papilloma Virus, Human
Prevention of HPV Types 16- and 18-related Cervical Cancer, Cervical Intraepithelial Neoplasia (CIN) 1/2/3, and Cervical Adenocarcinoma in Situ
A Study to Evaluate the Immunogenicity, Safety and Tolerability of Quadrivalent Human Papillomavirus Vaccine (V501) in Chinese Girls Aged 9-19 Years and Young Women Aged 20-26 Years (V501-213)
This study is designed to evaluate the immunogenicity, safety, and tolerability of Gardasil® (quadrivalent human papillomavirus [qHPV] vaccine, V501) in Chinese girls aged 9-19 years and young women aged 20-26 years.
- Trial name
- NCT03493542
- Testing
- V501
- Where
- China
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Human Papilloma Virus, Male
A Pilot Study Comparing the Effectiveness of Campus Intervention to Increase HPV Vaccine Rate Among College Aged Men
This is a study testing what type of message and access influences a young male to get the HPV vaccine. The investigators are conducting a 2 X 2 design These conditions are: Condition 1: Altruistic personal with direct…
- Trial name
- NCT02508701
- Testing
- Message X Onsite/Offsite Vaccination
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Carcinoma, Squamous Cell, Head and Neck Neoplasms
Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)
The purpose of this research study is to determine whether and when patients with human papilloma virus positive squamous cell cancer of the oropharynx treated with radiation and chemotherapy clear their human papilloma virus…
- Conditions
- Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms
- Trial name
- NCT02045186
- Testing
- Assessment of Oral HPV Infection
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
HIV, HIV Infections
A Study to Examine the Human Papillomavirus Types Exposure in Women From Southern Africa and Brasil
This is a study to determine what Human Papillomavirus HIV seropositive women in Botswana, South Africa and Brasil have been exposed to during their life. The Human Papillomavirus causes cervical cancer.
- Trial name
- NCT00840905
- Where
- 3 sites in Botswana, Brazil and 1 more
- Volunteers
- 487 people
- Sponsor
- Cynthia S Firnhaber
Vulvar Intraepithelial Neoplasia, Genital Warts
SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma
This pilot clinical study is to evaluate the efficacy \& safety of SR-T100 gel (2.3% of SM in Solanum undatum plant extract) in patients with VIN(s) or EGW(s).
- Trial name
- NCT01676792
- Testing
- SR-T100 gel with 2.3% of SM in Solanum undatum plant extract
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- National Cheng-Kung University Hospital
HIV (Human Immunodeficiency Virus), HPV
Feasibility Study Comparing Use of One Or Two Probes for Thermal Ablation Among Screen Positive Women Living With HIV in C1001P-CS2 Kenya
Cervical cancer disproportionately affects women in low- and middle-income countries (LMICs), particularly women living with HIV (WLWH) who have a 6-fold increased risk of cervical cancer compared to women in the general…
- Conditions
- HIV (Human Immunodeficiency Virus), HPV, Cervical Precancer
- Trial name
- NCT07468695
- Testing
- Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes
- Where
- Kenya
- Volunteers
- 300 people
- Sponsor
- Fred Hutchinson Cancer Center
Warts
Microwave Treatment of Common and Plantar Warts
This is a multi-center, open, randomized, parallel-group, controlled, blind-assessed trial of approximately 124 subjects that require treatment for up to 5 common or plantar warts.
- Trial name
- NCT05371834
- Testing
- Microwave Treatment (Swift System), Cryotherapy
- Where
- 6 sites in United States
- Volunteers
- 119 people
- Sponsor
- Blackwell Device Consulting
HIV, Human Papillomavirus
Immune Response to Bivalent and Tetravalent Human Papillomavirus Vaccine in HIV Infected Adults
The purpose of this study is to analyze and compare the immunogenicity of Bivalent and Tetravalent vaccines against Human Papillomavirus in HIV-infected adult persons.
- Trial name
- HIPAVAC (NCT01386164)
- Testing
- Gardasil, Cervarix
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Aarhus
Head and Neck Cancer, Precancerous Condition
Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or…
- Trial name
- NCT01302834
- Testing
- cetuximab, cisplatin, IMRT
- Where
- 185 sites in United States, Canada
- Volunteers
- 987 people
- Sponsor
- Radiation Therapy Oncology Group
Human Papillomavirus
Immunogenicity and Tolerability of V503 Versus GARDASIL (V503-009)
Primary objective: To demonstrate that administration of V503 induces non-inferior Geometric Mean Titers (GMTs) (for serum anti-HPV16 and anti-HPV18) compared to GARDASIL.
- Trial name
- NCT01304498
- Testing
- V503, GARDASIL
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia
Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV)
Up to 30% of Canadian women do not participate in Pap smear screening for cervical cancer prevention despite many being members of family practices and having access to family physicians.
- Trial name
- NCT01095198
- Testing
- offer of vaginal self collection, 2nd reminder letter for Pap testing
- Where
- Canada
- Volunteers
- 1,440 people
- Sponsor
- McMaster University
Barrett Esophagus
Prevalence of Human Papillomavirus in Barrett Esophagus Compared With Controls
The aim of this study was to determine whether the prevalence of Human PapillomaVirus (HPV) was increased in patients with Barrett esophagus compared with controls in a prospective study.
- Trial name
- Barrett (NCT02549053)
- Testing
- esophagus biopsies (pathologic and healthy zones), esophagus biopsies (healthy zones)
- Where
- 2 sites in France
- Volunteers
- 219 people
- Sponsor
- University Hospital, Angers
Human Papillomavirus (HPV), Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
AMG 319 in HPV Positive and Negative HNSCC
The purpose of this study is to determine whether a drug called AMG 319 has an effect on a patient's own immune response to head and neck cancer squamous cell carcinoma (HNSCC).
- Trial name
- NCT02540928
- Testing
- AMG 319 hydrate
- Where
- 5 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Cancer Research UK
Human Papillomavirus Infection
Quality Improvement Strategies to Increase Human Papillomavirus (HPV) Vaccination in Integrated Healthcare Delivery Systems
HPV vaccination coverage is at lower levels than the national goal. This study will evaluate the effectiveness of quality improvement strategies for increasing HPV vaccination coverage among adolescent within the context of large…
- Trial name
- NCT03887793
- Testing
- VACs
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cervical Cancer, Cervical Intraepithelial Neoplasia
HPV Integration Testing for Cervical Cancer Screening
The primary objective is to determine the sensitivity and specificity of the HPV Integration-based cervical screening for detection of high-grade cervical intraepithelial neoplasia (CIN), using colposcopic inspection as the…
- Trial name
- NCT02576158
- Testing
- TCT，HPV，colposcopic inspection
- Where
- China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Cervical Cancer, Throat Cancer
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
This is a phase II clinical trial to assess the clinical activity of immunotherapy with E7 TCR-T cells for metastatic HPV-associated cancers.
- Conditions
- Cervical Cancer, Throat Cancer, Oropharynx Cancer, Anal Cancer
- Trial name
- NCT05686226
- Testing
- E7 TCR-T cells, Aldesleukin
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Christian Hinrichs
Human Papillomavirus Infection
A Phase I Trial Evaluate the Safety and Tolerability Profile of HPV Vaccine
This study is to evaluate the safety and tolerability profile of Recombinant Nonavalent (Types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia Coli) in healthy women ages 18-45
- Trial name
- NCT05680454
- Testing
- Recombinant Nonavalent (Types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia Coli), Recombinant nonavalent Human Papillomavirus (Types 6,11,16,18,31,33,45,52,58) Vaccine
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Health Guard Biotechnology, Inc
Human Papilloma Virus, Cervical Neoplasm
Comparison of Cervical Pathologies in the Presence of High Risk Hpv Positivity
The only malignancy screening test among gynecological cancers is cervical cancer. Cytology examination and Hpv typing with smear are used as screening tests. Hpv positivity is detected in more than 90% of cervical cancers.
- Trial name
- NCT03895905
- Testing
- colposcopy and colposcopic biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 409 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Human Papillomavirus Vaccines
Community Pharmacists Vaccinate Against Cancer
Latino and African American populations have a higher rate of human papillomavirus (HPV) vaccine initiation; however, they have a significantly less likelihood of completing the vaccine series.
- Trial name
- CPVAC (NCT04072159)
- Testing
- Community Pharmacists Vaccinating Against Cancer
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Arizona State University
HPV Infection
Polyhexamethylene Biguanide Increases the Regression Rate of Human Papillomavirus (HPV) Infection
Human papillomavirus (HPV) infection is a worldwide problem strictly linked to the development of cervical cancer. Persistence of the infection is one of the main factors responsible for the invasive progression and women…
- Trial name
- NCT01571141
- Testing
- Monogin
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
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