Clinical trials: Paracentesis, open to volunteers
Severe Aortic Stenosis
Effect of Double-Tap Optimization on Valve Expansion and Hemodynamics in Balloon-expandable Transcatheter Aortic Valve Implantation: A Randomized Clinical Trial (DO-OPT TAVI Trial)
This study will compare two balloon inflation strategies during transcatheter aortic valve implantation (TAVI), a procedure used to replace a severely narrowed aortic valve through a catheter.
- Trial name
- NCT07912905
- Testing
- Double-Tap Balloon Post-dilatation, Conventional Single-Inflation TAVI
- Volunteers
- 250 people
- Sponsor
- Yonsei University
Obesity, Postoperative Gastrointestinal Dysfunction
Effect of TAP Block on GI Function After Sleeve Gastrectomy Using PRO-diGI Scale and Perlas Score
This prospective clinical study aims to evaluate the effect of Transversus Abdominis Plane (TAP) block on postoperative gastrointestinal function in patients undergoing laparoscopic sleeve gastrectomy.
- Trial name
- TAP (NCT07168538)
- Testing
- TAP Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Regional Anaesthesia, Transversus Abdominis Plane Block (TAP Block)
Transversus Abdominis Plane Block on Postoperative Analgesic Efficacy in Elderly Patients Undergoing Minimally Invasive Gastrointestinal Tumor Surgery
Elderly patients undergoing minimally invasive gastrointestinal tumor surgery face complex postoperative pain management due to age-related physiological decline and surgical particularities, where traditional opioids are prone…
- Conditions
- Regional Anaesthesia, Transversus Abdominis Plane Block (TAP Block), Pain, Postoperative
- Trial name
- NCT07013721
- Testing
- Transversus Abdominis Plane Block, TAPB
- Volunteers
- 102 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain, Acute
Effectiveness of Fentanyl-Added TAP Block in Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effectiveness of adding fentanyl to the TAP block in laparoscopic cholecystectomy cases.
- Trial name
- NCT06778668
- Testing
- TAP block with bupivacaine only, TAP block with bupivacaine and fentanyl
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uludag University
Pain Management, Fear
Effects of Virtual Reality and Helfer Skin Tap During Vaccination
The aim of this study was to detect and compare the effects of Virtual Reality and Helfer Skin Tap methods on pain, fear, anxiety, and satisfaction during the administration of Tetanus-Diphtheria vaccine to school-aged children.
- Conditions
- Pain Management, Fear, Anxiety, Satisfaction
- Trial name
- NCT06895330
- Testing
- Virtual Reality Group, Helfer Skin Tap Group
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Abdominal Surgery Patients, Transversus Abdominis Plane (TAP) Block
Plasma Kinetics of Levobupivacaine After Transversus Abdominis Plane (TAP) Block in Abdominal Surgery
This prospective single-center observational pharmacokinetic study will evaluate plasma levobupivacaine concentrations after ultrasound-guided transversus abdominis plane (TAP) block in adult patients undergoing elective…
- Conditions
- Abdominal Surgery Patients, Transversus Abdominis Plane (TAP) Block, Pharmacokinetic Analysis, Levobupivacaine
- Trial name
- LEVO-TAP-PK (NCT07581275)
- Testing
- Ultrasound-Guided Transversus Abdominis Plane Block with Levobupivacaine
- Volunteers
- 26 people
- Sponsor
- University of Liege
Hypertensive Disorder of Pregnancy, Pre-Eclampsia
Treatment With Aspirin After Preeclampsia: TAP Trial
The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through…
- Conditions
- Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia
- Trial name
- TAP (NCT06281665)
- Testing
- Low-dose aspirin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Malamo Countouris
Pediatric Feeding Disorder, Feeding Difficulties in Infants and Young Children
Validation of the D-TAP Parental Questionnaire for Early Screening of Pediatric Feeding Disorder in Hospitalized Children Aged 8 to 18 Months
This single-center observational study aims to evaluate the validity of the D-TAP parental questionnaire for early screening of pediatric feeding disorder (PFD) in hospitalized children aged 8 to 18 months.
- Trial name
- D-TAP (NCT07895914)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Inguinal Hernia Repair, Postoperative Pain
Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair
This prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after…
- Conditions
- Inguinal Hernia Repair, Postoperative Pain, TAP Block
- Trial name
- VIS-TAP-TAPP (NCT07264699)
- Testing
- Laparoscopic Transversus Abdominis Plane (TAP) Block with Bupivacaine
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
GRIN-related Disorders, GRIN1
TAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental Disorders
The goal of this clinical study is to find out whether L-serine dietary supplementation helps improve overall clinical functioning in children and young adults (2-30 years) with GRIN-related neurodevelopmental disorders…
- Conditions
- GRIN-related Disorders, GRIN1, GRIN2A, GRIN2B
- Trial name
- NCT07377032
- Testing
- L-serine
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 40 people
- Sponsor
- Meyer Children's Hospital IRCCS
Cesarean Section, Transversus Abdominis Plane (TAP) Block
The Effect of TAP Block on Maternal-Infant Bonding
Cesarean delivery is a common surgical procedure that is typically performed under spinal anesthesia. Postoperative pain management has a significant impact on both the mother's physical recovery and the quality of…
- Trial name
- NCT06858891
- Testing
- Transversus abdominis plane (TAP) block
- Volunteers
- 132 people
- Sponsor
- Adiyaman University Research Hospital
Laparoscopic Cholecystectomy, TAP Block
Laparoscopic-Assisted Transversus Abdominus Plane Block Versus Intraperitoneal Irrigation of Local Anesthetic for Patients Undergoing Laparoscopic Cholecystectomy
This study is being performed to investigate whether the administration of local anaesthetic into the muscles in the abdomen or onto squirting the local anaesthetic onto the liver following keyhole gallbladder surgery is more…
- Conditions
- Laparoscopic Cholecystectomy, TAP Block, Local Anesthetic
- Trial name
- NCT06714279
- Testing
- Tap Block - Bupivacaine, Intraperitoneal infiltration to liver
- Where
- Ireland
- Volunteers
- 144 people
- Sponsor
- Royal College of Surgeons, Ireland
Postoperative Pain After Cesarean Section
TAP vs. ESP Blocks for Post-Cesarean Analgesia
This study compares the effectiveness of two ultrasound-guided nerve blocks (TAP block and ESP block) versus standard pain management for relieving pain after a planned cesarean section.
- Trial name
- RCT-TAP-ESP-CS (NCT07853482)
- Testing
- Ropivacaine, Ultrasound-guided Nerve Block, Ketoprofen and Paracetamol
- Where
- Russia
- Volunteers
- 162 people
- Sponsor
- Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog
Decompensated Cirrhosis and Ascites
Low Dose Versus Standard Dose Albumin
Background: Liver cirrhosis with ascites is a major health problem, and large-volume paracentesis (LVP) is commonly performed for management of tense or refractory ascites.
- Trial name
- NCT07917819
- Testing
- Low dose Albumin, standard dose albumin
- Where
- Bangladesh
- Volunteers
- 25 people
- Sponsor
- Bangladesh Medical University
Postdural Puncture Headache, Epidural Analgesia, Obstetric
A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device
The purpose of the study is to learn more about a new device, the EpiZact Epidural Device, that may be helpful for reducing the likelihood of wet tap when a labor epidural is placed.
- Trial name
- NCT06729255
- Testing
- EpiZact-assisted epidural placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Postoperative Pain, Quality of Recovery
4-Point TAP Block vs. Combined RSB-OSTAP Block for Recovery After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a common keyhole surgery to remove the gallbladder. Although the cuts are small, patients can still have significant pain and nausea after the operation, which may delay recovery and discharge.
- Trial name
- NCT07264608
- Testing
- 4-Point TAP (4QTAP) Group, RSB + OSTAP Group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Konya City Hospital
Idiopathic Normal Pressure Hydrocephalus, Normal Pressure Hydrocephalus
Prediction of Response to Shunt Surgery in Normal Pressure Hydrocephalus Using Radscale and Lumbar Puncture
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder in older adults characterized by walking difficulties, cognitive decline, and urinary dysfunction.
- Trial name
- NCT07832877
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pain Management, Mtapa Block
M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery
Patients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room.
- Conditions
- Pain Management, Mtapa Block, TAP Block
- Trial name
- pain (NCT07311902)
- Testing
- TAP Block Group, M TAPA block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Dysmenorrhea, Pain
The Effect of Distraction Techniques Used in Intramuscular (IM) Injections on Pain in Adolescents Presenting to the Emergency Department With Dysmenorrhea: A Randomized Controlled Study
Brief Summary: This study investigates the effectiveness of non-pharmacological techniques for managing dysmenorrhea (menstrual pain) in adolescents.
- Conditions
- Dysmenorrhea, Pain, Distraction Methods
- Trial name
- "HSTT-SB Dysme (NCT06842329)
- Testing
- Halfer Skin Tape Technique, ShotBlocker Technique, Standard Intramusculer injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Duygu MEZDE