Clinical trials: Paraparesis
HTLV-1, Tropical Spastic Paraparesis
Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases
In this study the investigators are going to evaluate the efficacy pentoxifyline in HTLV-1 patients with neurological diseases: HAM/TSP or neurogenic bladder.
- Conditions
- HTLV-1, Tropical Spastic Paraparesis, Immune System Diseases, Physical Disability
- Trial name
- Pentox (NCT01472263)
- Testing
- Pentoxifylline
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Tropical Spastic Paraparesis, HTLV-1
Urological Physical Therapy in HTLV-1 With Urinary Symptoms
Urological physical therapy is described to improve urinary symptoms in patients with myelopathy or neurological dysfunction and to increase the quality of life.
- Trial name
- UROHTLV (NCT01651819)
- Testing
- Urological physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
HTLV-1-associated Myelopathy
Rituximab for HTLV-1-associated Myelopathy
Neuroprotective or anti-inflammatory strategies are invaluable in HTLV-1-associated myelopathy due to its rapid progression. We evaluated the efficacy of rituximab in patients with HTLV-1-associated myelopathy.
- Trial name
- NCT04004819
- Testing
- Rituximab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
HTLV-I Infections, HTLV-II Infections
MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study
This post-market study is intended to assess the performance of the HTLV Blot 2.4 in repository serum/plasma specimens with neurological disorders (n=100) or an HTLV known positive infection (n=50).
- Conditions
- HTLV-I Infections, HTLV-II Infections, Human T-lymphotropic Virus 1, Human T-lymphotropic Virus 2
- Trial name
- NCT03226119
- Testing
- MP Diagnostics HTLV Blot 2.4
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- MP Biomedicals, LLC
Human T-Lymphotropic Virus Type 1 Associated Myelopathy
Rehabilitation in Patients With Human Lymphotropic Virus Type I
In our times, it is known that approximately 5% of patients seropositive for HTLV-1 may desengage a frame with several neurological disorders, which is called myelopathy associated with HTLV-1, characterized for gait, decreased…
- Trial name
- NCT04875403
- Testing
- Inspiratory muscle trainning, Exercise
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Metodista de Piracicaba
HTLV-I Infection
Raltegravir for HAM/TSP
Background: Human T-cell lymphotropic virus type 1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an infection of the spinal cord.
- Trial name
- NCT01867320
- Testing
- Raltegravir
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
HTLV-I-Associated Myelopathy
Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)
An open-label, non-randomised, uncontrolled, proof-of-concept study of patients with HTLV-I-associated myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
- Trial name
- NCT01343355
- Testing
- Tamibarotene
- Where
- Japan
- Volunteers
- 15 people
- Sponsor
- St. Marianna University School of Medicine
Spastic Parapareses
Transcutaneous Direct Current Stimulation of the Spinal Cord for Treatment of Spasticity in Multiple Sclerosis
The current research is aimed at using Transcutaneous Spinal Direct Current Stimulation (tSDCS) as complementary therapeutic tool in the treatment of spasticity in multiple sclerosis.
- Trial name
- NCT04287244
- Testing
- Transcutaneous Spinal Direct Current Stimulation
- Volunteers
- 40 people
- Sponsor
- Lebanese American University
Cerebral Palsy, Paraparesis, Spastic
Effects of Therapeutic Music Combined With Loaded Sit-to-Stand Resistance Exercise for Children With Spastic Diplegia
The purpose of study is to investigate the effects of PSE Music with a "home-based" loaded STS exercise program on the functional strength, gross motor function, daily participation, exercise involvement, motor control, and gait…
- Trial name
- NCT01367327
- Testing
- Loaded sit-to-stand exercise, Synchronized music
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- National Taiwan University Hospital