Clinical trials: Paraplegia, Spinal
Spinal Cord Injury, Obesity
Effect of Intense Multi-modal Training on Bone Health and Quality of Life in Persons With Spinal Cord Injury
Bone loss is a common secondary complication of spinal cord injury (SCI), and treatments used to reverse this condition have equivocal effectiveness.
- Trial name
- NCT01386762
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- California State University, San Marcos
Spinal Cord Injuries
Biofeedback for Wheelchair Users
This study will evaluate movement of the arm and forces put through the hand during activities performed in a manual wheelchair.
- Trial name
- NCT02700178
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Motor Complete Spinal Cord Injury
The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI)
The purpose of this study is to determine whether a three times per week, 2 month robotic assisted treadmill gait training program, will beneficially affect the fitness, physical and psychological well-being, and the vascular and…
- Trial name
- NCT01349478
- Testing
- LOKOMAT
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Dr. Gabriel Zeilig
Aortic Aneurysm, Thoracoabdominal
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Aortic aneurysms represent the most common and dangerous aortic diseases. Although conventional aortic repair techniques cure the disease, there is a high risk of paraplegia particularly in extensive thoracoabdominal aneurysms…
- Trial name
- PAPAartis (NCT03434314)
- Testing
- Minimally-Invasive Segmental Artery Coil-Embolization
- Where
- 29 sites in Austria, France and 7 more
- Volunteers
- 500 people
- Sponsor
- University of Leipzig
Spinal Cord Injury, Paraplegia
The Safety of ahSC in Chronic SCI With Rehabilitation
The purpose of this study is to assess the safety of autologous human Schwann cell (ahSC) transplantation in participants with chronic SCI.
- Conditions
- Spinal Cord Injury, Paraplegia, Quadriplegia, Tetraplegia
- Trial name
- NCT02354625
- Testing
- Autologous human Schwann cells
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- W. Dalton Dietrich
Spinal Cord Injuries, Spinal Cord Compression
Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment Study
The SciExVR study will evaluate the potential benefit of autologous bone marrow derived stem cells (BMSC) in the treatment of spinal cord injury with evidence of impaired motor or sensory function.
- Conditions
- Spinal Cord Injuries, Spinal Cord Compression, Spinal Cord Ischemia, Spinal Cord Diseases
- Trial name
- SciExVR (NCT03225625)
- Testing
- Paraspinal, Paraspinal EX, Paraspinal VR
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- MD Stem Cells
Spinal Cord Injury, Tetraplegia
Study of the Impact of the Use of a Corset on the Respiratory Function of Patients With Spinal Cord Injury
Corsets are often used in the management of patients with a spinal cord injury. They may help to rigidify the patients' trunk which might help some patients to sit upright; their use may also reduce the sensation of dyspnea some…
- Conditions
- Spinal Cord Injury, Tetraplegia, Paraplegia
- Trial name
- Garchoise (NCT01569360)
- Testing
- Corset
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injury
Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait
Spinal cord injuries are anatomically mostly incomplete, showing tissue bridges of the spinal cord at the injury site. Of the 60% functionally incomplete patients, about half face a life in the wheelchair.
- Trial name
- DBS-SCI (NCT03053791)
- Testing
- Deep brain stimulation in mesencephalic locomotor region, Implantation of a Deep brain stimulation system
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University of Zurich
Paraplegia, Spinal Cord Injuries (SCI)
Safety and Performance Evaluation of ReWalk Reciprocating Gait Orthosis (RGO)
ReWalk suit developed by Argo Medical Technologies is designed to enable people with lower limb disabilities to carry out routine ambulatory functions (stand, walk etc.); it can be used by people with disabilities such as spinal…
- Trial name
- NCT01251549
- Testing
- ReWalk - a motorized exoskeleton suit
- Where
- 2 sites in United States, Italy
- Volunteers
- 32 people
- Sponsor
- ReWalk Robotics, Inc.
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.
Diabetes Mellitus, Body Composition
Body Composition Assessment in Spinal Cord Injury
The purpose of this research is to evaluate different methods of measuring body composition (amount of fat, muscle, bone, and water in your body) and to determine relationships between body composition and other medical problems…
- Conditions
- Diabetes Mellitus, Body Composition, Tetraplegia, Paraplegia
- Trial name
- NCT00957762
- Testing
- Body composition
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Spinal Cord Injury, Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI (WINY)
This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT07222033
- Testing
- Hands-free exoskeleton
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy
A Patient Centric Motor Neuron Disease Activities of Daily Living Scale
The purpose of this study is to learn about rates of patient-reported disease progression in patients with motor neuron diseases (amyotrophic lateral sclerosis, progressive muscular atrophy, primary lateral sclerosis, hereditary…
- Conditions
- Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02852278
- Testing
- Web-based Survey
- Volunteers
- 410 people
- Sponsor
- University of South Florida
Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
This study will use a magnetic resonance imaging technique called nuclear magnetic spectroscopy (H-MRS) to define the pathology and progression of primary lateral sclerosis, hereditary spastic paraplegia and amyotrophic lateral…
- Conditions
- Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
- Trial name
- NCT00023075
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injury, Traumatic Spinal Cord Injury
Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)
The purpose of this research study is to measure the tolerability and preliminary efficacy of a drug, galantamine, to treat metabolic syndrome (MetS) by reducing circulating inflammation in people with spinal cord injury (SCI).
- Conditions
- Spinal Cord Injury, Traumatic Spinal Cord Injury, Paraplegia and Tetraplegia, Metabolic Syndrome
- Trial name
- NCT07625332
- Testing
- Galantamine Hydrobromide Extended Release
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Paraplegia, Spinal Cord Injuries
Effect Of Magnetic Therapy In Bladder Dysfunction And Quality Of Life In Paraplegic Patients
Each study subject will undergo baseline urodynamic testing (UDS) at the beginning of the study to confirm the diagnosis of a neurogenic bladder with DSD and establish baseline bladder functions.
- Trial name
- NCT06169969
- Testing
- magnetic therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Central Cord Injury Syndrome, Central Spinal Cord Syndrome
Intermittent Positive-Pressure Breathing Effects in Patients With High Spinal Cord Injury
Background: To determine whether intermittent positive-pressure breathing (IPPB) improved lung compliance, work of breathing, and respiratory function in patients with recent high spinal cord injury (SCI).
- Trial name
- NCT00476866
- Testing
- intermittent positive-pressure breathing (IPPB)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University of Versailles
Spinal Cord Injuries, Gait Disorders, Neurologic
Safety and Feasibility of TWIICE Rise - Phase 2
The aim of this study is to assess the safety and the feasibility of two versions of TWIICE Rise for exoskeleton-assisted ambulation in patients with a spinal cord injury.
- Trial name
- NCT07461259
- Testing
- TWIICE Rise
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- TWIICE
Cardiovascular Disease
Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols
1. Measurements of peak oxygen uptake (VO2peak) during passive leg cycling (PLC) combined with arm crank ergometry (ACE), leg vascular occlusion (100mmHg above systolic BP) combined with ACE, and FES isometric contractions…
- Trial name
- NCT00987155
- Testing
- Ergometry
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Spinal Cord Injuries, Paraplegia, Spinal
Modeling, Optimization, and Control Methods for a Personalized Hybrid Walking Exoskeleton
The central objective of this study is to validate new algorithms that coordinate between functional electrical stimulation (FES) and the exoskeleton during sitting-to-standing, walking, and standing-to-sitting movements.
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Paraplegia, Incomplete
- Trial name
- NCT04453943
- Testing
- Exoskeleton Walking - with or without FES, Exoskeleton Sitting to Standing - with or without FES
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University