Clinical trials: Parasomnia
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of a Mask Seal/Mask for the Treatment of Obstructive Sleep Apnea (OSA)
This investigation is designed to evaluate the performance as well as the patients overall acceptance of the seal/mask.
- Trial name
- NCT03092921
- Testing
- F&P Mask Seal, F&P Mask
- Where
- New Zealand
- Volunteers
- 18 people
- Sponsor
- Fisher and Paykel Healthcare
Hypertension,Essential, Obstructive Sleep Apnea
A Cardiosleep Research Program on Obstructive Sleep Apnea, Blood Pressure Control and Maladaptive Myocardial Remodeling
The objective of this proposal is to evaluate whether mandibular advancement device (MAD) is non-inferior to continuous positive airway pressure (CPAP) in the treatment of obstructive sleep apnea (OSA) and blood pressure…
- Trial name
- CRESCENT (NCT04119999)
- Testing
- Mandibular Advancement Device, Continuous Positive Airway Pressure
- Where
- Singapore
- Volunteers
- 321 people
- Sponsor
- National University of Singapore
Sleep Apnea, Cardiovascular Diseases
Platelet Activation and Circadian Rhythms of Clotting-Fibrinolysis Factors in Patients With Sleep Apnea Syndrome
The objective of the study is to define and compare clotting- fibrinolysis patterns, platelet function markers and endothelial dysfunction in patients with SAHS before and after treatment and normal controls age and weight…
- Trial name
- NCT00456287
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Insomnia Disorders
Evaluating the Efficacy and Safety of Daridorexant Transition From BZRAs in Insomnia Patients（EASY-TIP）
Brief Summary: This study is a prospective, multicenter, open-label cohort study designed to evaluate the efficacy and safety of transitioning adult patients with insomnia from benzodiazepine receptor agonists (BZRAs) to…
- Trial name
- EASY-TIP (NCT07733414)
- Testing
- Daridorexant
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Xuanwu Hospital, Beijing
Pregnancy, Sleep Apnea Syndrome
Detection of Sleep Apnea Syndrome (OSA) in Pregnant Women and Assessment of Impact of OSA on Pregnancy Course
To assess prevalence of obstructive sleep apnea during pregnancy and its impact on prgnancy course and materno foetal wellbeing.
- Conditions
- Pregnancy, Sleep Apnea Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT02649933
- Testing
- Watch PAT 200
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Chronic Insomnia
Effect of Yoga in Chronic Insomnia
This study will evaluate the effect of the yoga in participants with chronic insomnia. The primary objective is to determine whether adding yoga to standard care improves insomnia severity, as measured by the Insomnia Severity…
- Trial name
- NCT07419152
- Testing
- Yoga-intervention, Stretching Exercises
- Where
- India
- Volunteers
- 72 people
- Sponsor
- All India Institute of Medical Sciences
Obstructive Sleep Apnea
Trans Nasal Insufflation for the Treatment of Snoring
This research is being done to examine if a nasal cannula can be used to keep the throat open during sleep, thereby treating sleep apnea.
- Trial name
- TNI (NCT00832026)
- Testing
- Trans Nasal Insufflation (TNI) [nasal canula]
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Fibromyalgia
Effect of Reflexology on Pain and Sleep Disorders in Females With Fibromyalgia
This randomized controlled trial aims to investigate the effect of foot reflexology on pain and sleep disorders in Egyptian female patients with fibromyalgia.
- Trial name
- REFLEX-FM (NCT07614945)
- Testing
- Foot Reflexology, Conventional Physical Therapy, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Obstructive Sleep Apnea
Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness
In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.
- Trial name
- Muscle-OSA (NCT06334601)
- Testing
- Tests of upper airway collapsibility and muscle responsiveness.
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Auxologico Italiano
Obstructive Sleep Apnea
New Pharmacological Treatment for Obstructive Sleep Apnea
This study will determine if mirtazapine, a unique antidepressant that does not disturb sleep, will improve obstructive sleep apnea (OSA). The design is randomized, crossover, double blind, and placebo controlled.
- Trial name
- NCT00108498
- Testing
- mirtazapine
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Sleep Disturbance in Hospitalized Antepartum Patients
Sleep Improvement Intervention for Hospitalized Antepartum Patients
This project seeks to further study the effects of a hospital-based protocol for improving sleep in high-risk antepartum patients as piloted by Lee and Gay (2017).
- Trial name
- NCT04485728
- Testing
- Sleep Improvement Protocol Intervention for Hospitalized Antepartum Patients
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Child Development, Sensory Processing
Development, Sensory Profile, and Sleep Quality in Preschool Children Across Different Caregiving Models
This observational study aims to examine developmental status, sensory processing, and sleep quality in preschool children aged 3 to 6 years across different caregiving models.
- Conditions
- Child Development, Sensory Processing, Sleep Quality, Caregiving Models
- Trial name
- NCT07511465
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea
Impact of Atrial Fibrillation Ablation on Sleep Parameters.
Assessment of Sleep Parameters Using Polygraphy in Patients with Paroxysmal Atrial Fibrillation Qualified for Pulmonary Vein Isolation - A Prospective Observational Study: Afib Ablation and Hypopnea Index - The "AAHI" Study…
- Conditions
- Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea, Pulmonary Vein Isolation
- Trial name
- AAHI (NCT07259200)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Primula Clinics
Obstructive Sleep Apnea
Effect of CPAP Treatment in Women With Moderate-to-severe OSA.
The purpose of this study is to determine whether Continuous Positive Airways Pressure (CPAP) improves quality of life, cardiovascular (blood pressure) and metabolic profile (glucose and lipid metabolism) in females with…
- Trial name
- NCT02047071
- Testing
- Continuous positive airways pressure
- Where
- Spain
- Volunteers
- 307 people
- Sponsor
- Francisco Campos-Rodriguez
Pain, Osteoarthritis, Hip
Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee
This clinical trial tests the pain relieving effectiveness of OROS hydromorphone, a once-daily formulation of a strong opioid against placebo in patients, who are suffering from pain due to osteoarthritis of the hip or the knee…
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00980798
- Testing
- OROS hydromorphone HCl
- Where
- 12 sites in Czechia, Romania and 2 more
- Volunteers
- 288 people
- Sponsor
- Janssen-Cilag International NV
Chronic Obstructive Pulmonary Disease
Safety of Ramelteon in Subjects With Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if ramelteon has respiratory depressant effects in subjects with moderate to severe chronic obstructive pulmonary disease.
- Trial name
- NCT00316992
- Where
- 8 sites in United States
- Volunteers
- 25 people
- Sponsor
- Takeda
Stress, Burnout
An Efficacy Trial of the MindFi App for Stress, Well-being, and Sleep Quality in Working Adults
90% of Asian workers report high levels of stress in an "always-on" culture. Stress and burnout are risk factors that account for 10-20% of health expenditure and threaten work longevity in the world's fastest growing economies.
- Trial name
- NCT05085132
- Testing
- MindFi app: Standard content, Mindfi app: Standard content without practice
- Where
- Singapore
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Obesity Hypoventilation Syndrome (OHS)
Average Volume-assured Pressure Support as Rescue Therapy in Obesity Hypoventilation Syndrome
It remains unclear whether CPAP therapy should be prescribed if significant hypoxemia persists during CPAP titration, despite optimization of upper airway obstructive events, if maximum CPAP pressure is reached.
- Trial name
- AVAPS (NCT06442163)
- Testing
- AVAPS study was performed within 1 week of the CPAP titration attempt failure, using the auto-titrating EPAP (AE), the OmniLab Advanced +, System One device (Philips Respironics, Murrysville, PA, U.S.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Adenotonsillectomy, Obstructive Sleep Apnea (OSA)
Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea
Emphasize that the usage of multimodal analgesia in managing perioperative pain in children with mild to moderate Obstructive Sleep Apnea undergoing adenotonsillectomy may achieve the same efficacy of fentanyl with less…
- Conditions
- Adenotonsillectomy, Obstructive Sleep Apnea (OSA), Fentanyl, Opioid
- Trial name
- NCT07435493
- Testing
- Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Restless Legs Syndrome
A Post-Market Study for Long-Term Effectiveness and Safety of the TOMAC System for RLS
Multi-center post-market, observational study to assess the long-term effectiveness and safety of the NTX100 TOMAC System for patients with Restless Legs Syndrome.
- Trial name
- THRIVE (NCT06076499)
- Testing
- NTX100
- Where
- 7 sites in United States
- Volunteers
- 325 people
- Sponsor
- Noctrix Health, Inc.
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