Clinical trials: Parasomnia
Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
Skeletal Effects of Chronic Night Shift
The specific aim of this observational study is to characterize changes in bone turnover makers (BTMs), bone mineral density (BMD), and bone microarchitecture in a cohort of nurses during their first year of night compared to day…
- Trial name
- ACORN (NCT05091021)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Massage, Sleep Quality
Shoulder Massage After Cholecystectomy
Purpose The aim of this study is to determine the effect of shoulder massage administered to patients after laparoscopic cholecystectomy on pain and sleep quality. Design The study was designed as a randomized controlled trial.
- Conditions
- Massage, Sleep Quality, Laparoscopic Cholecystectomy, Shoulder Pain
- Trial name
- SMALC (NCT06480149)
- Testing
- SMALC, no application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Psychological Distress, Depression - Major Depressive Disorder
Internet-based Support for Adjustment to Prostate Cancer
The study aims to study the efficacy of internet-based cognitive behavior therapy (ICBT) in reducing subjective distress and comorbid psychiatric symptoms in men diagnosed with prostate cancer.
- Conditions
- Psychological Distress, Depression - Major Depressive Disorder, Insomnia, Anxiety
- Trial name
- ISAC (NCT06766526)
- Testing
- Internet-based cognitive behavioral therapy, Non-directive support
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Linkoeping University
Alzheimer Disease, Insomnia Disorder
Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease
DARIDOR-ALZ is a phase IV clinical trial designed to evaluate both the efficacy and safety of daridorexant, a selective dual orexin receptor antagonist that blocks the actions of the orexin neuropeptides at both orexin-1 and…
- Conditions
- Alzheimer Disease, Insomnia Disorder, Sleep
- Trial name
- DARIDOR-ALZ (NCT05924425)
- Testing
- Daridorexant 50 mg, Polysomnography, Neuropsychological assessment
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Montpellier
Pulmonary Disease, Chronic Obstructive, Obesity Hypoventilation Syndrome
Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.
The purpose of this study is to analyze whether the treatment of metabolic alkalosis with acetazolamide in intubated patients with chronic obstructive pulmonary disease (COPD) or with obesity hypoventilation syndrome (OHS)…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Obesity Hypoventilation Syndrome, Metabolic Alkalosis
- Trial name
- TRAMA (NCT01499485)
- Testing
- Acetazolamide
- Where
- 8 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Hospital Son Llatzer
Valve Heart Disease, Awakening Early
Prospective Evaluation of Volatile Sedation After Heart Valve Surgery
Cardiac surgery is a complex operative procedure with a substantial risk of postoperative complications, so that patients undergoing valve surgery are usually transferred to the intensive care unit postoperatively.
- Trial name
- NCT04958668
- Testing
- Post-operative intensive care using volatile sedation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Sleep Disorder; Breathing-Related, Heart Failure
Patients With Heart Failure With Preserved Ejection Fraction Adherence to ASV Therapy (PEP ASV)
This is a prospective, single-arm, unblinded pilot study and registry that aims to demonstrate adherence to adaptive servo-ventilation (ASV) therapy in patients with moderate to severe sleep disordered breathing who have been…
- Trial name
- PEP-ASV (NCT04133350)
- Testing
- Active Patient Engagement
- Where
- 4 sites in United States, Germany
- Volunteers
- 2 people
- Sponsor
- Thomas Jefferson University
Sleep Apnea, Obstructive; Post-Traumatic Stress Disorders
Obstructive Sleep Apnea and Arousal Threshold in Patients With Post-traumatic Stress Disorder
Obstructive sleep apnea (OSA) has traditionally been attributed only to a collapsible upper airway. However, it is increasingly recognized that multiple additional non-anatomical mechanisms contribute to the disease.
- Trial name
- NCT02699138
- Testing
- Trazodone, Epiglottic catheter
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Insomnia, COVID - 19
A Prospective Study: Tai-chi and Post-COVID Insomnia
The goal of this study is to see if Tai-Chi exercises (a type of Chinese martial arts) can help people suffering from insomnia after COVID-19 when added with cognitive-behavioral therapy (CBT) and drugs compared to CBT and drugs…
- Trial name
- insomnia (NCT06776276)
- Testing
- Tai Chi exercises
- Where
- Egypt
- Volunteers
- 337 people
- Sponsor
- Alexandria University
Sleep Disturbances, Aging
Low-intensity Hippocampal Transcranial Ultrasound Stimulation for Managing Cognitive and Sleep Dysfunction in Preclinical Alzheimer's Disease
Background: Sleep disturbances, as a common symptom, can jeopardize the brain health and cognitive function and even lead to cognitive impairments in older adults.
- Conditions
- Sleep Disturbances, Aging, Cognitive Impairment, Mild
- Trial name
- NCT07298876
- Testing
- Low-intensity transcranial ultrasound stimulation
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Insomnia
Effects of Ramelteon (8mg) Alone and in Combination With Multi-Component Behavioral Therapy on Sleep and Circadian Phase in Patients With Chronic Insomnia
The specific aims of the proposed study are to compare the sleep, daytime functioning, and circadian phase effects of ROZEREMTM (ramelteon/TAK-375) a selective MT1/MT2 melatonin receptor agonist in humans alone and in combination…
- Trial name
- CBT (NCT01180855)
- Testing
- Rozerem 8mg, Rozerem 8mg in combination with Multi Component Behavior Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arizona
Obstructive Sleep Apnea Syndrome
Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children
The purpose of this study is to investigate the effect of treatment with a steroid and antibiotic on the size of the tonsils and symptoms of children with OSAS.
- Trial name
- NCT00456339
- Testing
- Prednisolone and amoxicillin/clavulanate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Virtual Reality, Pregnancy
The Effect of Virtual Reality Glasses on Sleep Quality and Anxiety Level in High-risk Pregnant Women
This study aims to determine the effect of watching nature videos accompanied by natural sounds (music) through virtual reality (VR) headsets on sleep quality, state anxiety, and trait anxiety levels in high-risk pregnant women.
- Conditions
- Virtual Reality, Pregnancy, Anxiety, Sleep Quality
- Trial name
- VRPregAnxSlp (NCT06996457)
- Testing
- VR
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Akdeniz University
Anxiety Depression, Alcohol Abuse
CBD Oil for Reducing Emotional Impact of COVID-19
Our purpose is to conduct a 4-arm placebo-controlled clinical trial to investigate the relative clinical efficacy of 300 mg. of pure hemp-derived CBD isolate, 300 mg. of full spectrum CBD oil, 300 mg.
- Conditions
- Anxiety Depression, Alcohol Abuse, Substance Abuse, Anger
- Trial name
- CBDOIL (NCT04603781)
- Testing
- CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Sleep Apnea, Glaucoma
Long-term Observation of Ophthalmic Changes in Patients With Obstructive Sleep Apnea
The ophthalmic changes during long-lasting sleep apnea are lacking in description and assessment. The investigators intend to observe patients for a long time and observe if the changes in eye tissues are progressing over the…
- Conditions
- Sleep Apnea, Glaucoma, Ocular Hypertension
- Trial name
- NCT03928665
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Wroclaw Medical University
Sleep Apnea Hypopnea Syndrome, Physical Activity
Effect of an Aerobic Exercise Program in Patients With Moderate-severe Sleep Apnea
In this paper, it is postulated that in sedentary patients with moderate-severe sleep apnea diagnosed by a sleep test, an increase in physical activity stimulated by the use of a pedometer during a period of 6 months can reduce…
- Trial name
- SAH-2014 (NCT03997877)
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Dentofacial Deformities, Sleep Disorder
Interaction Between Body Posture and Nocturnal Sleeping Disorders in Dysgnathic Patients
The role of head posture has been demonstrated in patient with dentofacial deformities. However, the relationship between body posture and jaw disorders is unclear.
- Conditions
- Dentofacial Deformities, Sleep Disorder, Posture
- Trial name
- NCT03532828
- Testing
- polysomnography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Laboratoire de Biomécanique Georges Charpak
Pulmonary Disease, Chronic Obstructive
Changes in Dyspnea, Activity and Sleep in COPD by Video-Based Breathing Exercises
Chronic Obstructive Pulmonary Disease (COPD) is one of the most prevalent and high-mortality chronic diseases worldwide. Symptoms such as dyspnea, cough, sleep disturbances, fatigue, restricted activity levels, anxiety, and…
- Trial name
- NCT06477367
- Testing
- Video-Based Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bartın Unıversity
Obstructive Sleep Apnea
Use of Sleep Endoscopy to Predict Outcomes of Pediatric Adenotonsillectomy
Pediatric obstructive sleep apnea (OSA) is associated with heavy snoring and brief pauses in breathing during sleep. It affects at least 1-3% of the general pediatric population with greater prevalence among certain high risk…
- Trial name
- NCT02693977
- Testing
- Sleep Endoscopy
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Oregon Health and Science University
Sleep Apnea Syndromes
Effect of Compression Stockings on the Number of Apneas/Hypopneas Per Hour of Sleep in Patients With Syndrome Obstructive Sleep Apnea/Hypopnea as Compared to no Treatment
The sleep apnea-hypopnea syndrome is characterized by the occurrence, during sleep, of abnormally frequent episodes of interruption of ventilation (apnea), or significant reduction in ventilation (hypopnea).
- Trial name
- NCT05477719
- Testing
- Wearing of specific compression stockings
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sigvaris France
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