Clinical trials: Parasomnia
Generalized Anxiety Disorder
CannaRiver CBD Calm for Anxiety, Sleep, and Well-Being in Adults With Generalized Anxiety Disorder
This open-label, single-group, non-randomized interventional study will evaluate longitudinal changes in anxiety symptoms, sleep quality, psychological well-being, treatment adherence, tolerability, and safety in adults with…
- Trial name
- CR-GAD-60 (NCT07821840)
- Testing
- Cannabidiol (CBD) With Cannabinol (CBN) and Cannabigerol (CBG) Oral Tincture (CannaRiver CBD Calm)
- Volunteers
- 60 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Sleep Apnea, Obstructive, Primary Open-angle Glaucoma
IOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airway Pressure
Sleep apnea is characterized by repetitive episodes of decreased or interrupted airflow in the upper airways during sleep. Obstructive sleep apnea syndrome (OSAS) is the most common sleep-related breathing disorder and is…
- Trial name
- NCT01560975
- Testing
- SENSIMED Triggerfish®
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sensimed AG
Perioperative Anxiety, Postoperative Pain
Perioperative Effect of Music in Patients Undergoing General Anesthesia
Anxiety is a transient emotional state characterized by feelings of tension, apprehension, nervousness, fear, and heightened activation of the autonomic nervous system in response to a specific current or potential event or…
- Trial name
- EMBAG (NCT05572437)
- Testing
- Music Therapy
- Where
- Spain
- Volunteers
- 151 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Therapy by Stimulation of the Hypoglossal Nerve
Continuous positive airway pressure (CPAP) is the gold standard to normalize breathing during sleep in patients with obstructive sleep apnea syndrom (OSA). Many patients will not tolerate or will not accept CPAP.
- Trial name
- AIRSTIM (NCT03844295)
- Testing
- Activated Inspire® Upper Airway Stimulation System, Inactivated Inspire® Upper Airway Stimulation System
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Grenoble
Sleep Quality, Stress Reduction
EXOMIND (BTL-699-2) for the Improvement of Sleep Quality and Reduction of Stress
The goal of this clinical trial is to evaluate whether the treatment with BTL-699-2 device is able to improve sleep quality and reduce stress in adults above the age of 22 years.
- Trial name
- NCT07027657
- Testing
- Treatment with BTL-699-2
- Where
- 3 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Sleep Apnea, Obstructive
Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment
The investigators will compare two alternatives designed to maximize adherence to continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) - peer-support administered in groups, versus individual…
- Trial name
- NCT02538419
- Testing
- CPAP + Peer Support, CPAP + Individual Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Overweight and Obesity, Cardiovascular Diseases
Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC)
The investigators hypothesize that weight loss obtained with the French RNPC weight reduction program is beneficial for the general health of overweight/obese patients in the medium term.
- Conditions
- Overweight and Obesity, Cardiovascular Diseases, Metabolic Disease, Diabete Type 2
- Trial name
- SCOOP-RNPC (NCT05857319)
- Testing
- Nutritional Psycho-Behavioral Reeducation Program
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Groupe Éthique et Santé
Obstructive Sleep Apnea of Adult
Impact of Intermittent Hypoxia on the Function of the Phagocytes
Patients with treatment-naive obstructive sleep apnea (OSA) who need continuous positive airway pressure (CPAP) therapy on clinical basis are included as well as healthy controls without OSA.
- Trial name
- NCT03618719
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Posttraumatic Stress Disorder, Insomnia
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
This pilot pre-post trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of…
- Conditions
- Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
- Trial name
- NCT05516277
- Testing
- Behavioral Sleep Education Intervention
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Survivor of Childhood Cancer, Insomnia
Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia
This pilot study will assess the usefulness and potential effectiveness of using transcutaneous auricular vagus nerve stimulation (tVNS) for treating insomnia in adult survivors of childhood acute lymphoblastic leukemia (ALL).
- Conditions
- Survivor of Childhood Cancer, Insomnia, Acute Lymphoblastic Leukemia (ALL)
- Trial name
- NCT07191119
- Testing
- Soterix tVNS device, Sleep Quality, Neurocognitive and mental health outcomes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Jude Children's Research Hospital
Sleep Apnea, Sleep Apnea, Obstructive
Evaluation of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
This proof-of-concept study is being performed to evaluate whether the hypoglossal nerve can be stimulated using a small series of electrodes placed surgically via a percutaneous approach.
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Sleep Disorder
- Trial name
- NCT06283030
- Testing
- Hypoglossal nerve stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Invicta Medical Inc.
Sleep Disorders, Fibromyalgia
The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
Fibromyalgia is a condition of chronic widespread pain, sleep disturbance and fatigue. Most of the patients with fibromyalgia complain of either non-restorative sleep or complaints of disturbed sleep due to pain.
- Conditions
- Sleep Disorders, Fibromyalgia, Sleep
- Trial name
- NCT01234675
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mansoor Ahmed M.D.
Hypertension
Antihypertensive Effect of Continuous Positive Airway Pressure in Resistant Hypertensive Patients With Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) has been linked to resistant hypertension, but the effect of treatment of OSAS on the resistant hypertension have no been established.
- Trial name
- NCT00929175
- Testing
- active CPAP
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Non-24 Hour Sleep-Wake Disorder, Blindness
Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects
The aim of this placebo-controlled randomized study was to evaluate the efficacy of Circadin™ 2 mg in improving total night sleep duration and stabilizing the circadian clock phase in totally blind subjects with non-24 hour…
- Trial name
- NCT00972075
- Testing
- melatonin (Circadin)
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Eating Attitudes, Lifestyle Risk Reduction
Eating, Sleep, Attitudes, and Stress Risk in Physical Therapy Students
The goal of this observational study is to assess how eating attitudes, sleep attitudes, and perceived stress contribute to early indicators of cardiovascular risk among undergraduate physical therapy students aged 18-30.
- Conditions
- Eating Attitudes, Lifestyle Risk Reduction, Perceived Stress
- Trial name
- EHSAR-S (NCT07303244)
- Testing
- complete validated questionnaires
- Where
- Egypt
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cairo University
Insomnia, Morbid Obesity
M-Health Administered Sleep Treatment to Enhance Recovery in Bariatric Populations (MASTER)
This study is a longitudinal clinical trial designed to assess the feasibility of sleep intervention (Cognitive Behavioral Therapy for Insomnia (CBT-I)) in individuals with insomnia following bariatric surgery.
- Trial name
- MASTER (NCT04619771)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stony Brook University
Central Sleep Apnea
Pathophysiological Study of CSA in Adults With pLVEF
Sleep apnea is classically divided into obstructive and central apnea, according to the persistence or otherwise of respiratory movements and the existence or not of pharyngeal collapse during apnea.
- Trial name
- PHENOSAX (NCT03919344)
- Testing
- Critical airway closure pressure (Pcrit) measurment, Acoustic pharyngometry, High density surface electroencephalogram neural mapping
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Insomnia Disorder, Chronic Insomnia
Internet-Based Cognitive Behavioral Therapy for Insomnia in Persian-Speaking Adults
This study will test whether an internet-based cognitive behavioral therapy for insomnia (ICBT-I) delivered through the Persian-language web program "Omid" can improve sleep in Persian-speaking adults with insomnia.
- Trial name
- ICBT-I (NCT07431034)
- Testing
- Omid Internet-Based CBT-I Program
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Rasool Hamidi Choolabi
Delayed Sleep-Wake Phase Disorder
Pupillometry in Delayed Sleep Wake Phase Disorder
The goal of this observational study is to characterize the pupil light response in patients with delayed sleep-wake phase disorder.
- Trial name
- NCT06949644
- Testing
- Light and Citalopram
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Northwestern University
Obstructive Sleep Apnea Syndrome, Endothelial Dysfunction
Oxidative Stress and Endothelial Dysfunction in Obstructive Sleep Apnea
Patients with sleep apnea syndrome have repeated apneic events that induce periodic hypoxia-reoxygenation, drawing away an overproduction of oxidants.
- Conditions
- Obstructive Sleep Apnea Syndrome, Endothelial Dysfunction, Oxidative Stress, Intermittent Hypoxia
- Trial name
- SOREVAS (NCT00646971)
- Testing
- CPAP device
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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