Clinical trials: Parasomnias
Sleep, Sleep Inertia
Sensible Sleep: Measuring Alarm and Snooze Behavior in Teens Using Wearables and Smartphones
Pilot data suggests that working professionals and college students routinely use alarms and snooze. Alarm usage and snoozing is associated with several negative health biomarkers including lighter sleep, higher resting heart…
- Conditions
- Sleep, Sleep Inertia, Stress
- Trial name
- NCT04786678
- Testing
- Cell phone notification
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Notre Dame
Narcolepsy, Cataplexy
An Open Label Study of FT218 in Subjects With Narcolepsy
An Open Label Study to Evaluate Long-Term Safety and Tolerability of a Once Nightly Formulation of Sodium Oxybate for Extended-Release Oral Suspension (FT218) and the ability to switch from twice-nightly immediate release sodium…
- Conditions
- Narcolepsy, Cataplexy, Excessive Daytime Somnolence, Sleep Disorder
- Trial name
- RESTORE (NCT04451668)
- Testing
- FT218
- Where
- 29 sites in United States, Canada
- Volunteers
- 184 people
- Sponsor
- Avadel
Stress Disorders, Post-Traumatic, Combat Disorders
Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether prazosin will: reduce the incidence of nightmares and sleep disturbance increase functioning and sense of well being in combat-trauma exposed Operation Iraqi Freedom/Operation…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Sleep Disorders
- Trial name
- NCT00990106
- Testing
- prazosin hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Sleep
Effects of Napping in Pregnant Women With Sleep Disturbances on Offspring Neurodevelopment
To examine the effects of napping in pregnant women with sleep disturbances on offspring neurodevelopment, the researchers will recruit 80 pregnant women with sleep disturbances.
- Trial name
- NCT06514833
- Testing
- lifestyle recommendations to nap regularly, No recommendations to nap regularly
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Sleep Disorders in Children
Melatonin Adolescent Research Study
The present study will use a within-person, randomized cross-over experimental design to test the effects of exogenous melatonin supplementation on the sleep and daytime functioning of typically developing adolescents with short…
- Trial name
- MARS (NCT04588233)
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Loma Linda University
Endocrine Responsive Early Breast Cancer
Impact of Adjuvant Treatment With Aromatase Inhibitor on Sleep Disturbances in Postmenopausal Women With Endocrine Responsive Early Breast Cancer
Insomnia is common in Breast cancer patients during adjuvant therapy with aromatase inhibitor. However it is difficult to establish whether it is due to the knowledge of the disease or the treatment administred.
- Trial name
- NCT02166281
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Bruxism, Sleep
OstiSense Biosensor in Bruxism Reduction - A Clinical Study
The overall objective of the clinical studies with the OstiSense biosensor tool will be to evaluate whether the use of the OstiSense biosensor tool significantly reduces the number of sleep bruxism events per night as well as the…
- Trial name
- NCT03749928
- Testing
- OstiSense biosensor - active, OstiSensor biosensor - not activated
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sleep Disturbance
Feasibility of a Mobile App on Sleep
This study investigates the feasibility and effects of a mindfulness meditation mobile application on sleep for individuals reporting sleep disturbances.
- Trial name
- NCT04045275
- Testing
- Calm
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Sleep Disturbance
Blocking Blue Light in Pregnancy, Effects on Melatonin Profile and Sleep
Sleep disturbances are common in pregnancy, and the incidence increases during the third trimester. Light and specially the blue wavelengths of light, is affecting sleep and the circadian rhythm.
- Trial name
- NCT03114072
- Testing
- Blue-blocking glasses, Light grey control glasses
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Bruxism, Sleep Bruxism
Low-Level Laser Therapy Versus Occlusal Splint Therapy for Bruxism in Children
Many children grind or clench their teeth, especially during sleep. Doctors call this bruxism. It can wear down teeth and cause jaw pain. This study compared two treatments for bruxism in children.
- Trial name
- NCT07865845
- Testing
- Low-Level Laser Therapy (LLLT), Occlusal Splint
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sleep Disturbance
Perioperative Lignocaine and Sleep Disturbance
The aim of this clinical trial is to study the effect of an intravenous infusion of lidocaïne in a multimodal analgesic protocol on the architecture sleep during the first postoperative night.
- Trial name
- NCT03317912
- Testing
- Lidocaïne 2%
- Volunteers
- 40 people
- Sponsor
- University of Liege
Sleep Disturbance, Autism Spectrum Disorder
Community-Engaged Sleep Intervention for School-Aged Children With Autism Spectrum Disorder
As many as 78% of children with autism spectrum disorder (ASD) have significant sleep disturbance compared to 20% of children without ASD.
- Trial name
- NCT07007819
- Testing
- Modified Sleep and Circadian Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Case Western Reserve University
Grief, Anxiety
Online Multi-component Psychological Intervention for Prevention of Grief Disorder Due to COVID-19
This study evaluates the effectiveness of an online Multi-component psychological intervention, that is focused on providing self-support to the Mexican population for the prevention of complicated grief disorder, by reducing…
- Conditions
- Grief, Anxiety, Depression, Sleep Disturbance
- Trial name
- NCT04638842
- Testing
- Online Intervention Grief COVID-19
- Where
- Mexico
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Restless Legs Syndrome
A Study To Investigate The Effects Of End Stage Renal Disease And Hemodialysis On The Pharmacokinetics Of Ropinirole
This study will investigate the effects of severe renal impairment and hemodialysis on the characteristics of the drug, ropinirole.
- Trial name
- NCT00422994
- Testing
- ropinirole dosing for up to 28 days
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sleep Apnea Syndrome
Stair Stepping Exercise Training in Patients With Obstructive Sleep Apnea Syndrome
This 3-year prospective, randomized, control, longitudinal study is aimed to (1) examine the effect of stair stepping exercise training on cardiopulmonary fitness and sleep situation in patients with Obstructive Sleep Apnea…
- Trial name
- NCT00952172
- Testing
- stair stepping exercise
- Volunteers
- 47 people
- Sponsor
- Chang Gung Memorial Hospital
Sleep Bruxism
Evaluation of Muscle Activity, Bite Force and Salivary Cortisol in Children With Bruxism
Bruxism is a repetitive activity of the masticatory muscles characterized by grinding and/or clenching one's teeth or parafunctional movements of the mandible.
- Trial name
- Bruxism (NCT02757261)
- Testing
- Laser, Occlusal splint
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Major Abdominal Surgery, Postoperative Delirium (POD)
MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)
This study aims to determine whether, compared with placebo, the nighttime self-administration of a nasal dexmedetomidine is effective at inducing sleep and preventing postoperative delirium in high-risk patients.
- Conditions
- Major Abdominal Surgery, Postoperative Delirium (POD), Sleep Disturbances, Intranasal Dexmedetomidine
- Trial name
- MIDDIES (NCT07538284)
- Testing
- Dexmedetomidine
- Volunteers
- 400 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Cesarean Section, Restless Leg Syndrome
Neuraxial Anesthesia and Restless Leg Syndromes in Cesarean
The restless leg syndromes is a common sensorimotor disorder of unknown cause affecting approximately 10% of the population. Different literature had different views on the association between neuraxial anesthesia and the…
- Trial name
- NARELESS (NCT00872248)
- Testing
- Spinal anesthesia, Epidural anesthesia
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Nanjing Medical University
Mood Disturbance, Mood Change
Mood and Cognitive Effects of Psilocybin in Healthy Participants
This study is seeking to find the optimal microdose or low dose of psilocybin (magic mushrooms) that provides general enhancements to mood, memory, sleep, and other measures of general well-being without any hallucinogenic…
- Conditions
- Mood Disturbance, Mood Change, Sleep Disturbance, Drug Effect
- Trial name
- MELO (NCT05252598)
- Testing
- Psilocybin, Inonotus Obliquus Whole Extract
- Volunteers
- healthy volunteers welcome
- Sponsor
- Optimi Health Corporation