Clinical trials: Parathyroid Carcinoma
Rheumatic Disease, Neoplasms
Latest Imaging SPECT System Evaluation Phase 1
Monocentric study for the evaluation of a whole body CZT scintigraphy system.
- Conditions
- Rheumatic Disease, Neoplasms, Parathyroid Diseases, Pulmonary Embolism
- Trial name
- LISSE1 (NCT04704349)
- Testing
- Scintigraphy
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Parathyroid Gland Adenoma, Primary Hyperparathyroidism
Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism
This clinical trial studies the omission of intact parathyroid hormone testing during surgery in treating patients with primary hyperparathyroidism.
- Trial name
- NCT03011736
- Testing
- Laboratory Biomarker Analysis, Parathyroidectomy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Roswell Park Cancer Institute
Lung, Prostate, Breast, Colon, Pancreatic, Renal, Bladder,Thyroid, Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut) Cancer, Cancer of the Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut), Sarcoma Cancer
Optional Sub-study to Intraoperative Imaging With ICG Registry
The primary goal of this optional sub-study is to record what tissues fluoresce in the operating room, and then to identify if these lesions are cancer when the histopathology is performed.
- Conditions
- Lung, Prostate, Breast, Colon, Pancreatic, Renal, Bladder,Thyroid, Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut) Cancer, Cancer of the Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut), Sarcoma Cancer, Cancer of Neuro-onc, Parathyroid, Desmoid Tumors, Melanoma Cancer
- Trial name
- NCT02651246
- Testing
- data collection
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Parathyroid Adenoma, Thyroid Nodule
The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/Parathyroidectomy
The aim of this study was evaluated the feasibility of bilateral intermediate cervical plexus blockade to be anesthesia for simple thyroid/parathyroid surgery.
- Trial name
- NCT04905641
- Testing
- Bilateral intermediate cervical plexus block
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Parathyroid Carcinoma, Primary Hyperparathyroidism
Phase 3 Study of KHK7580 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Primary Hyperparathyroidism
To evaluate the efficacy of KHK7580 orally administered up to 24 weeks for hypercalcemia in patient with parathyroid carcinoma or primary hyperparathyroidism who are unable to undergo parathyroidectomy or relapse after…
- Trial name
- NCT03280264
- Testing
- KHK7580
- Where
- Japan
- Volunteers
- 18 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Primary Hyperparathyroidism, Parathyroid Adenoma
Treatment of Primary Hyperparathyroidism With Denosumab and Cinacalcet.
The only known cure for primary hyperparathyroidism is surgical removal of one or more parathyroid glands. Some patients however, do not fulfill criteria for surgery or do not want to undergo a procedure due to fear of the…
- Conditions
- Primary Hyperparathyroidism, Parathyroid Adenoma, Parathyroid Hyperplasia
- Trial name
- DENOCINA (NCT03027557)
- Testing
- Cinacalcet 30 mg Tablet, Denosumab Inj 60 mg/ml
- Where
- Denmark
- Volunteers
- 46 people
- Sponsor
- Peter Vestergaard
Thyroid Cancer, Thyroid Nodule
Minimizing Narcotic Analgesics After Endocrine Surgery
This research is being done to better understand and test if the investigators can minimize narcotic medication for controlling pain after thyroid or parathyroid surgery.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Neoplasms, Thyroid Goitre
- Trial name
- NCT03469310
- Testing
- Acetaminophen 500Mg Cap, Tylenol #3 Oral Tablet, Tramadol
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Minerva A Romero Arenas
Hyperparathyroidism, Parathyroid Adenoma
The Utility of 18F-fluorocholine PET/CT in the Imaging of Parathyroid Adenomas
We assessed sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid tissue in patients with primary hyperparathyroidism (PHPT).
- Trial name
- NCT04570033
- Testing
- We assessed sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid tissue in patients with primary hyperparathyroidism
- Volunteers
- 65 people
- Sponsor
- Military Institute od Medicine National Research Institute
Parathyroid, Intraoperative Monitoring
Protective Effect of Intraoperative Parathyroid Gland Auxiliary Recognition System in Thyroid Malignant Tumor Operation
This intraoperative parathyroid gland auxiliary recognition system uses the principle of parathyroid gland autofluorescence to assist surgeons in accurately identifying and protecting parathyroid glands during surgery, reducing…
- Conditions
- Parathyroid, Intraoperative Monitoring, Thyroid Cancer
- Trial name
- NCT04560426
- Testing
- Intraoperative parathyroid gland auxiliary recognition system
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Locally Advanced Adrenal Gland Pheochromocytoma, Locally Advanced Paraganglioma
Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers
This phase II trial studies how well 177Lu-DOTATATE works in treating patients with rare endocrine cancers that have spread from where they started to nearby tissue or lymph nodes (locally advanced), spread to other places in the…
- Conditions
- Locally Advanced Adrenal Gland Pheochromocytoma, Locally Advanced Paraganglioma, Metastatic Adrenal Gland Pheochromocytoma, Metastatic Paraganglioma
- Trial name
- NCT04106843
- Testing
- Lutetium Lu 177 Dotatate
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Hypercalcemia of Malignancy
Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium
The purpose of this study is to determine the potential of denosumab to treat Hypercalcemia of Malignancy in patients with elevated serum calcium who do not respond to recent treatment with intravenous bisphosphonates by lowering…
- Conditions
- Breast Cancer, Hypercalcemia of Malignancy, Colon Cancer, Endocrine Cancer
- Trial name
- NCT00896454
- Testing
- denosumab
- Where
- 24 sites in United States, Canada and 3 more
- Volunteers
- 33 people
- Sponsor
- Amgen
Intraoperative Parathyroid Scores System
Extended Application of Intraoperative Parathyroid Scores System(IPSS) in Thyroidectomy
after established the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy we further extented the clinical value of Intraoperative Parathyroid Scores System in Treatment decisions of calcium treatment time and…
- Trial name
- IPSS (NCT03191344)
- Testing
- with IPSS
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Fujian Medical University
Pleural Neoplasms, Mesothelioma
The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) has a growing incidence and in spite of early diagnostic, their outcome remains dismal. The evolution of MPM is often local with rare distant metastases.
- Conditions
- Pleural Neoplasms, Mesothelioma, Pneumothorax, Parathyroid Neoplasms
- Trial name
- NCT01776385
- Testing
- Blood sampling, Control Group
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Thyroid Cancer, Hypoparathyroidism
Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery
To study the protective effect of suture parathyroid marker method on the function of parathyroid gland in thyroid cancer surgery
- Conditions
- Thyroid Cancer, Hypoparathyroidism, Marker; Structural, Complication of Surgical Procedure
- Trial name
- NCT03514251
- Testing
- The suture marks the location of the parathyroid gland
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Bo Wang,MD
Parathyroid Carcinoma, Parathyroid Neoplasm
Parathyroid Cancer Versus Atypical Parathyroid Neoplasm; Investigating Their Clinical Characteristics and Biological Behavior
Objectives: 1. Identify the clinical characteristics of parathyroid (PTH) cancer and PTH atypical neoplasms 2. Investigate if PTH carcinoma and atypical neoplasm present a biological behaviour and have a different impact on the…
- Trial name
- NCT03046524
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Parathyroid Adenomas
High Intensity Focused Ultrasound (HIFU) for Parathyroid Adenoma
This study aims to determine whether HIFU treatment is a safe and effective alternative to an operation to remove all or part of the affected gland.
- Trial name
- NCT01291498
- Testing
- High Intensity Focused Ultrasound
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Oxford University Hospitals NHS Trust
Thyroid Cancer, Parathyroid; Absent
Intra-operative Rapid Identification of Lymph Node and Parathyroid
During surgery, a fine needle puncture was proceeded when suspicious nodes was found by clinician. Repeat the punction for 2-3 times from different orientation and then, Diff-quik staining or PTH immunochromatographic assay were…
- Conditions
- Thyroid Cancer, Parathyroid; Absent, Hypocalcemia, Hypoparathyroidism Postprocedural
- Trial name
- NCT03268785
- Testing
- Intraoperative identification method
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Pancreatic Cancer, Thymic Cancer
Genetic Evaluation of Families With Endocrine Cancers
This study is being conducted to identify altered genetic factors that may exist and influence endocrine cancers in unrelated MEN1 families with different cancers.
- Conditions
- Pancreatic Cancer, Thymic Cancer, Parathyroid Disease, MEN1 Syndrome
- Trial name
- MEN1 (NCT01794676)
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Jersey Shore University Medical Center
Intraoperative Parathyroid Scores System
Clinical Utility of Intraoperative Parathyroid Scores System in Thyroidectomy
Ready to establish the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy and study the clinical value of Intraoperative Parathyroid Scores System for thyroidectomy.
- Trial name
- IPSS (NCT03172312)
- Testing
- Different range of thyroid surgery
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fujian Medical University
Parathyroid Carcinoma, Hypercalcemia
An Intra-individual Titration Study of KRN1493 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Intractable Primary Hyperparathyroidism
This is an intra-individual titration study of KRN1493 to evaluate the safety and efficacy of KRN1493 for the treatment of hypercalcemia in patients with parathyroid carcinoma or intractable primary hyperparathyroidism (PHPT).
- Conditions
- Parathyroid Carcinoma, Hypercalcemia, Primary Hyperparathyroidism
- Trial name
- NCT01460030
- Testing
- Cinacalcet HCl
- Where
- Japan
- Sponsor
- Kyowa Kirin Co., Ltd.