Clinical trials: Parathyroid Dysfunction, open to volunteers
Velocardiofacial Syndrome, Williams Syndrome
The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome
The purpose of this study is to investigate the Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (VCFS), Williams Syndrome (WS)and Fragile X Syndrome Characterization, Treatment and Examining the Connection to…
- Conditions
- Velocardiofacial Syndrome, Williams Syndrome, Fragile X Syndrome
- Trial name
- VCFS (NCT00768820)
- Testing
- methylphenidate, fluoxetin, risperidone
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- The Chaim Sheba Medical Center
Common Variable Immunodeficiency (CVID), Primary Immune Regulatory Disorder
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
This is a research protocol that will examine Hematopoietic Stem Cell Transplantation (HSCT) using a reduced conditioning regimen (RIC) with total body Irradiation (TBI) in those diagnosed with Common Variable Immunodeficiency…
- Conditions
- Common Variable Immunodeficiency (CVID), Primary Immune Regulatory Disorder, Immune Dysregulation, DiGeorge Syndrome
- Trial name
- CVID/PIRD (NCT07284641)
- Testing
- Hematopoietic stem cell transplant (HSCT)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Paul Szabolcs
Hypoparathyroidism
Hypoparathyroidism Natural History Study
This is a prospective three-year natural history study of adults with hypoparathyroidism. The goal is to monitor patients with hypoparathyroidism to define end-organ damage in the context of the disease.
- Trial name
- SHINE (NCT05793853)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Thyroid Cancer
Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism
The study aims to test if use of autofluorescence imaging (AF) reduces the risk of developing hypoparathyroidism (hypoPT) following surgery for thyroid cancer, either total thyroidectomy (TT) or completion hemithyroidectomy (cHT).
- Trial name
- NCT06222606
- Testing
- Surgery with autofluorescence
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Aarhus University Hospital
Cholecystitis, Cholecystitis, Chronic
Shortwave Infrared Surgical Imaging Device Study
The goal of this observational study is to perform an in-human assessment of an investigational shortwave infrared (SWIR) imaging device, aimed to enhance the visualization of critical anatomical structures during surgical…
- Conditions
- Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism
- Trial name
- NCT07744425
- Testing
- Observational study of SWIR imaging device in surgery
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cision Vision, Inc.
Hypoparathyroidism Post-surgical
Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism
The aim of this study is to investigate the effect of daily treatment with Indapamide for 14 days on urinary calcium excretion in patients with post surgical hypoparathyroidisme.
- Trial name
- HYPOCARE treat (NCT07034677)
- Testing
- Indapamide 1.5 MG SR
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Lars Rejnmark
Endocrine Disease
Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.
- Trial name
- NCT03050762
- Testing
- Data Collection, Follow Up
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- M.D. Anderson Cancer Center
Hyperparathyroidism, Primary
Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism
The goal of this study is to address surgical health equity in historically marginalized participants with primary hyperparathyroidism (PHPT).
- Trial name
- NCT06562881
- Testing
- Scheduling Navigation, Without Scheduling Navigation
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Pennsylvania
Hypoparathyroidism, Pseudo Hypoparathyroidism
Institution of an Italian Multicenter Database of Patients Affected by Hypoparathyroidism or Pseudohypoparathyroidism
The goal of this observational study is to create, manage and analyze a multicenter national database of patients affected by hypoparathyroidism or pseudohypoparathyroidism, aimed at collecting and studying anamnestic…
- Trial name
- NCT06645899
- Where
- 41 sites in Italy
- Volunteers
- 600 people
- Sponsor
- F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore
Chronic Kidney Diseases, Hypertension
Integrated Diagnosis and Treatment of CKD on Outcomes
Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical…
- Conditions
- Chronic Kidney Diseases, Hypertension, Hyperglycemia, Hyperlipidemias
- Trial name
- NCT05242055
- Testing
- Integrated diagnosis and treatment for CKD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Capital Medical University
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Renal Osteodystrophy, Chronic Kidney Diseases
Precision Medicine Approaches to Renal Osteodystrophy
Treatment of renal osteodystrophy is impeded by the lack of practical and accurate tools to determine underlying bone turnover. Gold standard bone biopsy is not practical in the clinic for the vast majority of kidney disease…
- Conditions
- Renal Osteodystrophy, Chronic Kidney Diseases, CKD-MBD, Bone Turnover Rate Disorder
- Trial name
- PMaROD (NCT05880914)
- Testing
- miRNAseq analysis, Standard treatment for bone disorder
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Thomas Nickolas
Hypoparathyroidism, Pseudohypoparathyroidism
German Hypoparathyroidism Registry
Chronic hypoparathyroidism is a rare condition in which the parathyroid glands do not make enough parathyroid hormone (PTH). PTH helps control the levels of calcium and phosphate in the blood.
- Trial name
- HyPaReg (NCT07857460)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University Hospital Augsburg
Hypoparathyroidism
Translation and Validation of the Hypoparathyroidism Patient Experience Scales (HPES) Questionnaire in Greek
This is a crossectional study that will be conducted at several tertiary centers in Greece. To participate in the study, patients should be ≥18 years of age, fluent in Greek language, diagnosed with chronic HP, on optimal…
- Trial name
- HPES (NCT07160348)
- Testing
- Questionnaire and Physical Exam
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Amino-Acid Transport Disorder, Primary Hyperparathyroidism
Amino Acid Transporter System PET/CT Imaging in AATS-Related Diseases
To evaluate the potential usefulness of 11C/18F-MET/FET positron emission tomography/ computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various amino acid transporter system (AATS)-related…
- Conditions
- Amino-Acid Transport Disorder, Primary Hyperparathyroidism, Glioma
- Trial name
- NCT07379463
- Testing
- 11C/18F-MET/FET
- Where
- 3 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Hyperparathyroidism, Kidney Transplantation Recipients
Parathyroidectomy After Kidney Transplantation
This study aims to clarify whether surgical treatment of persistent hyperparathyroidism after kidney transplantation offers clinically meaningful benefits compared with a conservative treatment strategy.
- Trial name
- Para-KiT (NCT07415421)
- Testing
- Subtotal Parathyroidectomy, Conservative Management
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Aarhus University Hospital
AKI, CKD
Genetics in the Progression of Nephropathies
This study evaluates the role of genetic in the development and progression of different nephropaties with particular attention to: AKI CKD Hypertension ADPKD CKD-MBD Patients with decompensated heart failure undergoing either…
- Conditions
- AKI, CKD, Ckd-Mbd, CKD (Chronic Kidney Disease) Stage 5D
- Trial name
- NCT06416761
- Testing
- genetic polymorphisms
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Ospedale San Raffaele
Hyperparathyroidism, Parathyroid
Parathyroidectomy and Mobility Study
This study evaluates whether surgical removal of the parathyroid gland (parathyroidectomy) improves physical function and mobility in older adults with primary hyperparathyroidism (PHPT).
- Conditions
- Hyperparathyroidism, Parathyroid, Mobility
- Trial name
- NCT07103876
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Florida
Parathyroid Adenomas, Hyperparathyroidism, Primary
Parathyroid Adenoma Detection With Rubidium-82 Imaging
Assess the uptake of rubidium-82 in parathyroid adenomas.
- Trial name
- PARAGON (NCT07099404)
- Testing
- PET/CT imaging with rubidium-82
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Matthieu Pelletier-Galarneau, MD MSc
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy