Clinical trials: Parathyroidectomy
Hyperparathyroidism
Comparison of Two Methods of Parathyroidectomy for Primary Hyperparathyroidism
Parathyroid glands are small endocrine glands that secrete a hormone which controls blood calcium levels. Primary hyperparathyroidism (PH) is a common disorder whereby one or more of these glands may enlarge and overproduce their…
- Trial name
- NCT00006329
- Testing
- Minimally invasive radioguided parathyroidectomy
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Parathyroidectomy
Quality of Life (QOL) Following Parathyroid Surgery
The only established treatment for the complete resolution of hyperparathyroidism is the surgical removal of the affected glands.
- Trial name
- NCT00205452
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Wisconsin, Madison
Secondary Hyperparathyroidism
IOPTH Usefulness for Predicting Successful Surgery in Secondary Hyperparathyroidism
Secondary hyperparathyroidism (SHPT) is a multisystemic syndrome that affects calcium and bone homeostasis in patients with chronic kidney disease (CKD).
- Trial name
- NCT04484116
- Testing
- Intraoperative Paratohormone
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital General Ajusco Medio
Hyperparathyroidism, Hypertension
The Effect of Parathyroidectomy on Renal Function, Endothelial Function, and Blood Pressure
Secondary hyperparathyroidism (HPT) is a known complication of chronic renal failure. Elevated concentrations of parathyroid hormone (PTH) play a role not only in the pathogenesis of renal bone disease, but also in the…
- Trial name
- NCT00452049
- Testing
- parathyroidectomy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Primary Hyperparathyroidism
Minimally Invasive Radioguided Parathyroidectomy
The main purpose of this research study is to evaluate the effectiveness of a minimally invasive surgical approach to removing parathyroid gland(s).
- Trial name
- MIRP (NCT01530919)
- Testing
- Minimally invasive radioguided parathyroidectomy
- Where
- United States
- Volunteers
- 856 people
- Sponsor
- University of Louisville
Hyperparathyroidism, Primary, Parathyroidectomy
Alterations in Muscle's Functional Characteristics After Parathyroid Surgery for Primary Hyperparathyroidism.
Protocol title: Alterations in functional characteristics of the muscle tissue following surgery for primary hyperparathyroidism.
- Trial name
- NCT03091140
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Primary Hyperparathyroidism, Multinodular Goiter
Object Assessment of Improvement in Non-Specific Symptoms After Parathyroidectomy for Primary Hyperparathyroidism
Wearable electronic devices are becoming more prevalent in daily life, as they offer real time information on physiological parameters such as heart rate, activity level, oxygenation, and sleep patterns for their users.
- Trial name
- NCT06337825
- Testing
- Activity Tracker (Fitbit), HbA1C, The PROMPT Questionnaire
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Secondary Hyperparathyroidism;Parathyroidectomy
Total Parathyroidectomy With Autotransplantation Versus Total Parathyroidectomy Alone for Secondary Hyperparathyroidism
Total parathyroidectomy with autotransplantation (TPTX+AT) and Total parathyr- oidectomy alone (TPTX) are the common surgical procedures.The purpose of the study was to compare the long-term benefits of surgery between the two…
- Trial name
- NCT04922892
- Testing
- Parathyroidectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Secondary Hyperparathyroidism Due to Renal Causes, End Stage Renal Failure
Retrospective Analysis of Quality of Life Changes in Patients Undergoing Parathyroidectomy for End-Stage Renal Disease
The purpose of this study is to characterize changes in quality of life in patients who had undergone parathyroidectomy for secondary hyperparathyroidism due to end-stage renal disease, based on data extracted from an established…
- Trial name
- NCT07151664
- Testing
- Quality of life progression after parathyroidectomy
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Secondary Hyperparathyroidism, Chronic Kidney Disease Mineral and Bone Disorder
Impact of Parathyroidectomy on Cardiovascular Calcification in Dialysis-dependent Patients
This is a prospective cohort study aimed to evaluate change of cardiovascular calcification after parathyroidectomy in patients with end-stage renal disease on dialysis compared with control group on conservative treatment.
- Conditions
- Secondary Hyperparathyroidism, Chronic Kidney Disease Mineral and Bone Disorder, Vascular Calcification, Dialysis
- Trial name
- NCT03937349
- Where
- Russia
- Volunteers
- 63 people
- Sponsor
- Saint Petersburg State University, Russia
Primary Hyperparathyroidism
NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism
Primary hyperparathyroidism (PHPT) is a prevalent endocrine disorder, with an estimated prevalence of 0.86% in the United States. The only definitive treatment for PHPT is parathyroidectomy.
- Trial name
- NCT07812649
- Testing
- NIRAF-camera
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Parathyroid Adenoma, Thyroid Nodule
The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/Parathyroidectomy
The aim of this study was evaluated the feasibility of bilateral intermediate cervical plexus blockade to be anesthesia for simple thyroid/parathyroid surgery.
- Trial name
- NCT04905641
- Testing
- Bilateral intermediate cervical plexus block
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Primary Hyperparathyroidism
OPG/Soluble RANKL (sRANKL) and Bone Mineral Density in Primary Hyperparathyroidism
The purpose of this study is to determine whether osteoprotegerin and RANKL (receptor activator of nuclear factor-κB ligand) are involved in bone remodeling in patients with primary hyperparathyroidism (PHPT), and whether…
- Trial name
- NCT01889134
- Testing
- Sedron (alendronate), Parathyroidectomy
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- Wroclaw Medical University
Hemodialysis
Sub-total Parathyroidectomy Reduces Vascular Calcification in Haemodialysis Patients
The aim of this study was to evaluate whether successful sub-total parathyroidectomy retards cardiovascular calcification in patients with hemodialysis and to investigate the mechanism .
- Trial name
- NCT01140490
- Testing
- Sub-total Parathyroidectomy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Guangdong Provincial People's Hospital
Secondary Hyperparathyroidism
Parathyroidectomy vs Cinacalcet in the Treatment of Secondary Hyperparathyroidism Post Renal Transplantation
The hypothesis of this study is that subtotal parathyroidectomy using minimally invasive surgery is superior to cinacalcet for the treatment of persistent secondary hyperparathyroidism (HPT) post renal transplant, with minimal…
- Trial name
- NCT01178450
- Testing
- Subtotal parathyroidectomy, Cinacalcet
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Josep M Cruzado
Cure Rate, Complication Rate
Thermal Ablation Versus Parathyroidectomy for Primary Hyperparathyroidism
This study is a prospective, multicenter study designed to compare the efficacy and safety of surgical treatment versus ablation therapy (including radiofrequency ablation and microwave ablation) for patients with primary…
- Conditions
- Cure Rate, Complication Rate, Efficacy and Safety
- Trial name
- NCT06708871
- Testing
- Thermal ablation, Parathyroidectomy
- Volunteers
- 520 people
- Sponsor
- Chinese PLA General Hospital
Parathyroid Adenoma, Hypercalcemia
Preoperational Fine Needle Aspiration of Pathological Parathyroid Gland
Identification and localization of pathological parathyroid gland before parathyroidectomy is traditionally done by a combination of two methods: ultrasound and sestamibi scan.
- Trial name
- NCT03516747
- Testing
- pre operative parathyroid hormone level measurement, pre operative parathyroid cytology, parathyroid hormone level measurement
- Where
- Israel
- Sponsor
- HaEmek Medical Center, Israel
Hypoparathyroidism Postprocedural, Hypocalcemia
Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
The objective of this ongoing randomized controlled trial is to examine whether the use of intra-operative NIR(near infrared) camera can reduce the number of patients who experience transient or persistent hypoparathyroidism…
- Conditions
- Hypoparathyroidism Postprocedural, Hypocalcemia, Surgery--Complications
- Trial name
- NCT04193332
- Testing
- NIR optical imaging camera
- Where
- 2 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Primary Hyperparathyroidism
Impact of Parathyroidectomy on Renal Function
Primary hyperparathyroidism (PHPT) is a disorder of one or more of the parathyroid glands. The parathyroid gland(s) becomes overactive and secretes excess amounts of parathyroid hormone (PTH).
- Trial name
- PARA-REIN (NCT04798092)
- Testing
- parathyroidectomy
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Hyperparathyroidism
Swalqol in Primary Hyperparathyroidism
Swallow related quality of life before and after parathyroidectomy will be evaluated in patients with primary hyperparathyridism.
- Trial name
- NCT03968510
- Testing
- parathyroidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Uşak University