Clinical trials: Parenteral Nutrition
Malaria
Study of SAR97276A in the Treatment of Uncomplicated and Severe Malaria in Adults and Children.
The objective of the study is to assess the efficacy and safety of SAR97276A in severe malaria in pediatric patients. Before treating pediatric patients with severe malaria, the efficacy and safety of SAR97276A will be first…
- Trial name
- NCT00739206
- Testing
- SAR97276A
- Where
- 4 sites in Benin, Burkina Faso and 2 more
- Volunteers
- 113 people
- Sponsor
- Sanofi
Infections, Total Parenteral Nutrition
Immune Modulation by Parenteral Lipids
Immune modulating properties of parenteral lipid emulsions seem to contribute to the increased risk for infections which remains associated with the use of total parenteral nutrition.
- Trial name
- NCT00734916
- Testing
- Parenteral lipid emulsion (Omegaven), Parenteral lipid emulsion (Intralipid), Parental lipid emulsion (Saline 0.9%)
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Short Bowel Syndrome
Characterization of the Long-term Safety, Efficacy, and Pharmacodynamics Revestive® in the Management of Short Bowel Syndrome Pediatric Patients
The purpose of this study is to evaluate if the treatment could maximize intestinal absorption, minimize the inconvenience of diarrhea, and avoid, reduce or eliminate the need for parenteral support (PS) to achieve normal growth…
- Trial name
- REVE (NCT03562130)
- Testing
- Teduglutide
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Implementation of OPAT in Germany
Outpatient Parenteral Antibiotic Therapy in the Metropolitan Area of Cologne
Many infectious diseases require a therapy that is administered intravenously due to a lack of oral treatments. Affected patients often have to stay weeks or even months in hospital just for receiving their therapy although they…
- Trial name
- NCT04002453
- Testing
- Outpatient Parenteral Antibiotic Therapy
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Cologne
Venous System, Venous Access
A Retrospective, Observational, Monocenter, Study to Describe the Utilization and Overall Safety and Performance of POLYSITE®/SEESITE® Implantable Ports
This study is a retrospective, observational, monocenter case series. The purpose of this study is to collect clinical data to describe the use of POLYSITE® and SEESITE® devices and verify overall safety and performance.
- Conditions
- Venous System, Venous Access, Chemotherapy, Antibiotics
- Trial name
- NCT05519787
- Testing
- Central Veinous access devices' insertion
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Perouse Medical
Tetralogy of Fallot (TOF), Alpha-tocopherol
Effect of Parenteral Alpha-Tocopherol in the Definitive Surgery of Tetralogy of Fallot
Introduction: Tetralogy of Fallot (ToF) correction with cardiopulmonary bypass (CPB) poses a risk of ischemia-reperfusion injury, especially in cyanotic myocardium.
- Conditions
- Tetralogy of Fallot (TOF), Alpha-tocopherol, Cardiac Surgery
- Trial name
- NCT07194304
- Testing
- alpha-Tocopherol, Sterile Water for Injection
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Infant,Premature, Parenteral Nutrition
Personalized vs Standardized PN for Preterm Infants >1250g
Preterm infants (gestational age between 189 and 258 days) with a birth weight (BW) greater than 1250 grams will be randomized to personalized-parenteral nutrition (P-PN) or standardized-parenteral nutrition (S-PN).
- Conditions
- Infant,Premature, Parenteral Nutrition, Growth
- Trial name
- NCT03693287
- Testing
- Standardized-parenteral nutrition (S-PN), Personalized-parenteral nutrition (P-PN)
- Where
- 3 sites in Italy, Spain
- Volunteers
- 150 people
- Sponsor
- Ospedali Riuniti Ancona
Short Bowel Syndrome
Efficacy and Safety of PJ009 in Patients With Short Bowel Syndrome Requiring Parenteral Nutrition
The main aim of this clinical trial is to assess the efficacy and safety of PJ009 in patients aged ≥14 with short bowel syndrome (SBS) requiring parenteral nutrition.
- Trial name
- NCT06512584
- Testing
- PJ009
- Where
- 8 sites in China
- Volunteers
- 72 people
- Sponsor
- Chongqing Peg-Bio Biopharm Co., Ltd.
Liver Transplantation, Total Parenteral Nutrition
Supplements SMOF in TPN for Liver Transplantation Recipients
Liver transplantation (LT) is one of the widely recognised and leading treatments for end-stage liver disease. Nutrition impacts its success.
- Conditions
- Liver Transplantation, Total Parenteral Nutrition, End-stage Liver Disease
- Trial name
- NCT04572373
- Testing
- SMOFlipid
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Chang Gung Memorial Hospital
Vitamin D Deficiency
Vitamin D Supplementation in Pediatrics. Oral or Parenteral! D2 or D3
A study will be performed on Vitamin D deficient/ insufficient Egyptian children to compare the efficacy of oral and parenteral forms of Ergocalciferol and cholecalciferol in raising serum 25(OH) D levels in these subjects
- Trial name
- NCT06176157
- Testing
- vitamin D2, vitamin D3
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Urinary Bladder Neoplasms, Cystectomy
Radical Cystectomy, Nutrition and Convalescence
The purpose of this study is to determine whether a goal directed nutritional intervention can reduce the convalescence period for patients undergoing radical cystectomy (RC).
- Conditions
- Urinary Bladder Neoplasms, Cystectomy, Bladder Cancer
- Trial name
- NCT02238886
- Testing
- Parenteral nutrition. SMOFKABIVEN infusion in central vene. Fresenius Kabi
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Short Bowel Syndrome, Malabsorption
Home Parenteral Nutrition (HPN) Families' Mobile Distance Connections to Care Research
The purpose of this study is to test Mobile Technologies in Assisting Patients \& Family Caregivers in Healthy Living and complex home care by connecting to information and professionals from a distance.
- Conditions
- Short Bowel Syndrome, Malabsorption, Malnutrition
- Trial name
- NCT01900288
- Testing
- HPN Group Clinic Appointments using Mobile Devices (experimental)
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Kansas Medical Center
Preterm Infants
Hepatic Function and Bile Acid in Preterm Infants Receiving Parenteral Lipids Emulsion
The etiology of parenteral nutrition-associated cholestasis(PNAC)although elusive is thought to be multifactorial, and proposed theories also include problems arising from lipid emulsions, leading us to explore alternative…
- Trial name
- NCT01786759
- Testing
- ClinOleic, Intralipid
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Premature Birth
Parenteral Nutrition Light Protection and Premature Outcomes
Investigators propose a prospective study to investigate the effect of full light protection of the PN on cholestasis and other oxidative stress associated diseases in premature infants when they receive PN for more than one…
- Trial name
- NCT04525872
- Testing
- Full parenteral nutrition light protection of the bag, tubing and lipids
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Gastrointestinal Fistula, Enteral Nutritional Support
Enteral Versus Parenteral Nutrition in the Conservative Treatment of Upper Gastrointestinal Fistula After Surgery
The incidence of clinically significant anastomotic leaks (AL) after upper gastrointestinal (GI) surgery is approximately 4 % - 20 %, and the associated mortality can be as high as 80 % .
- Trial name
- NUTRILEAK (NCT03742752)
- Testing
- Enteral nutrition, Parenteral nutrition
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
Taurolidine Lock Solution
Survey of Practices Regarding the Use of Taurolidine Lock Solutions in Patients With Insertion of a Peripherally Inserted Central Catheter (PICC) in a Vascular Access Unit
The primary objective of this study is to describe current practices regarding the administration of taurolidine lock solutions in relation to medical prescriptions for patients who have undergone peripherally inserted central…
- Trial name
- TAURO-USE2 (NCT07259421)
- Volunteers
- 45 people
- Sponsor
- University Hospital, Grenoble
Critical Illness, Organ Dysfunction
The Effect of the Timing of Supplemental Parenteral Nutrition on the Prognosis of Critically Ill Patients (T-SPN)
This multicenter, randomized controlled trial aims to evaluate whether early initiation of supplemental parenteral nutrition (SPN) (on day 4 of ICU admission) compared to late initiation (on day 8) can reduce 28-day all-cause…
- Conditions
- Critical Illness, Organ Dysfunction, Enteral Nutrition Intolerance, Inadequate Nutritional Intake
- Trial name
- NCT07085455
- Testing
- Early Supplemental Parenteral Nutrition (SPN), Late Supplemental Parenteral Nutrition (SPN)
- Where
- 2 sites in China
- Volunteers
- 946 people
- Sponsor
- Dong Zhang
Oral Aversion, Enteral Nutrition
The Multi-disciplinary Approach of Children With Feeding Difficulties and Tube Feeding in UZB Between 2000 and 2021
The goal of this Retrospective Cohort Study is to compare the patients from before and after the implementation of the pre-convention for infants with feeding difficulties needing tube feeding or having received tube feeding in…
- Conditions
- Oral Aversion, Enteral Nutrition, Parenteral Nutrition, Tube Feeding
- Trial name
- ORALAV (NCT06161350)
- Testing
- Structured multi-disciplinary approach
- Where
- Belgium
- Volunteers
- 330 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cancer, Infection
Primary Prevention of Infections Related to Chambers Implantable Catheter by a Taurolodine Lock in Patients With Cancer Receiving Parenteral Nutrition
The therapeutic management of patients with cancer often requires the establishment of a chamber implantable catheter. Infections are the main complication of these catheters.
- Trial name
- NCT02255318
- Testing
- Taurolock
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Malnutrition, Surgery
Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients
Malnutrition is common in surgical patients. Many studies have shown a clear association between malnutrition and poor surgical outcomes.
- Trial name
- OPPortuNity (NCT03926949)
- Testing
- Parenteral Nutrition, Standard Nutrition Care
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of Alberta