Clinical trials: Pareses
Muscular Dystrophies, Scapular Dyskinesis
Evaluation of a Textile Scapula Orthosis
Shoulder instability due to muscle weakness is a common problem in disorders of the upper extremities. During arm motion, the scapula acts as a dynamic base for the humeral head.
- Conditions
- Muscular Dystrophies, Scapular Dyskinesis, Muscular Dystrophy, Facioscapulohumeral, Muscle Weakness
- Trial name
- ScapOrthosis (NCT04154098)
- Testing
- Scapula orthosis assistance, Manual scapula assistance, No assistance
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 8 people
- Sponsor
- Swiss Federal Institute of Technology
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
Weaning Failure
Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU
Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it can lead to respiratory muscle weakness and atrophy, which are…
- Trial name
- TrainToWean (NCT04658498)
- Testing
- Procedure: Usual Care (UC), Procedure: UC + HI-IMT
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Stroke Nos Without Residual Deficits
The Use of Brace to Retrain Hemiparetic Gait
The purpose of this study is to verify if the incorporation of a new brace, which assists in gait rehabilitation, can contribute to the rehabilitation process for stroke patients.
- Trial name
- NCT02082938
- Testing
- Bracing
- Volunteers
- 12 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Stroke, Cerebrovascular Accident (CVA)
Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- tVNS (NCT03592745)
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Unilateral Cerebral Palsy
Wereables for Upper Limb Functionality in Hemiparesis
The project is configured as a national interventional study that aims to determine the effectiveness of an intervention strategy using wearable technology, tailored to improve function (WeFun-wearable), on the spontaneous use of…
- Trial name
- WeFun (NCT06872736)
- Testing
- WeFun-wearable activated, WeFun-wearable desactivated
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidade da Coruña
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to compare two different treatments -- Contralataterally Controlled Functional Electrical Stimulation (CCFES)…
- Conditions
- Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00891319
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- MetroHealth Medical Center
Sedentary Behaviors, Core Muscle Weakness
Pilates for Sedentary Individuals
The global rise in physical inactivity represents an escalating public health crisis, with the proportion of insufficiently active adults projected to reach 35% by 2030.
- Trial name
- NCT07666919
- Testing
- Pilates exercise, Walking exercise
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Liver Transplantation, Postoperative Recovery
Effects of The Telerehabilitation-Based Exercise Program in Liver Transplant Patients
This randomized controlled study aims to evaluate the effects of a telerehabilitation-based exercise program on muscle strength, exercise capacity, fatigue level, and cognitive status in adult liver transplant recipients.
- Conditions
- Liver Transplantation, Postoperative Recovery, Muscle Weakness, Functional Capacity
- Trial name
- NCT07425314
- Testing
- Telerehabilitation Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Hasan Kalyoncu University
Stroke
Efficacy of Modified FUT Protocols in Relation to CR Protocol
There are some treatments after Stroke. Among these, use forced therapy (FUT), which is based on overcoming learned disuse by reintroduction of the paretic upper limb in the performance of daily activities.
- Trial name
- NCT02441374
- Testing
- Tubular mesh., Classical kinesiotherapy.
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo
Polymyositis, Dermatomyositis
Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis
This study determined the efficacy, safety, tolerability and the PK profile of BAF312, a novel immunomodulator, in polymyositis and dermatomyositis patients who were not responsive to traditional immunosuppressive and/or…
- Trial name
- NCT01148810
- Testing
- BAF312
- Where
- 6 sites in United States, Czechia and 3 more
- Volunteers
- 18 people
- Sponsor
- Novartis Pharmaceuticals
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Stroke, Hemiparesis
Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study
The aims of the study are to recruit five participants with stroke upper limb hemiparesis and determine the effects on neural reorganisation of a three-week music intervention using electroencephalogram measures.
- Conditions
- Stroke, Hemiparesis, Home-based
- Trial name
- NCT06223529
- Testing
- Therapeutic Instrumental Music Performance
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Anglia Ruskin University
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss
Blood Flow Restriction Training in Rehabilitation Patients
Occlusion training, resistance exercise performed with a specialized venous tourniquet, leads to beneficial changes in muscle at low resistance and minimal stress on the nearby joint.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
- Trial name
- NCT02174770
- Testing
- Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Brooke Army Medical Center
Diabetes Mellitus, Type 2
Krill Oil and Muscle Weakness in Type 2 Diabetes
The age-related loss of muscle mass and function, sarcopenia, has several deleterious effects, such as a reduction in the quality of life and an increase in the incidence of falls, often leading to hospitalisation.
- Trial name
- KRIMD (NCT04943523)
- Testing
- Krill Oil, Vegetable Oil
- Where
- Kuwait
- Volunteers
- 150 people
- Sponsor
- Dasman Diabetes Institute
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis
Heart Failure
Exercise Capacity and Fatigue in Heart Failure Patients With and Without Inspiratory Muscle Weakness
In patients with heart failure, diaphragm dysfunction contributes to decreased quality of life while simultaneously increasing morbidity and mortality.
- Trial name
- NCT06428227
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gazi University
Stroke, Hemiplegia
Brain Stimulation and Rehabilitation for Adults With Chronic, Severe Arm Motor Impairment After Stroke
This pilot study will examine a combination therapy for adults with chronic, severe motor impairment of an arm after stroke. The intervention will combine brain stimulation with physical rehabilitation of the arm on the side of…
- Conditions
- Stroke, Hemiplegia, Hemiparesis
- Trial name
- NCT03538795
- Testing
- iTBS&eCIMT
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Alabama at Birmingham