Clinical trials: Paresthesia
Paresthesia and Hypoesthesia
Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery
Why is this study being done? Paresthesia is a change in sensation that can cause numbness, tingling, or loss of feeling in a part of the body.
- Trial name
- NCT07592897
- Testing
- Vitamin B Complex
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Chronic Pain
BurstDR Spinal Cord Stimulation Versus Sham in Established Responders
This study aims to determine whether ongoing BurstDR spinal cord stimulation (SCS) provides pain relief beyond sham stimulation in patients with chronic pain who are established responders to BurstDR therapy.
- Trial name
- NCT07779733
- Testing
- BurstDR Spinal Cord Stimulation
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Umeå University
Atopic Dermatitis
Tolerance and Efficacy Open-label Study With RV4421B, in Various Populations With Atopic Dermatitis for 12 Weeks
Pierre Fabre Laboratories have developed a cream with medical device status, RV4421B-EV0407 indicated for the treatment of eczemas, including atopic eczema, contact eczema and chronic hand eczema.
- Trial name
- NCT07014007
- Testing
- RV4421B- EV0407
- Where
- Mauritius
- Volunteers
- 105 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Ovarian Neoplasms, Breast Neoplasms
A Study to Determine the Management of Palmar-plantar Erythrodysesthesia (PPE) in Patients With Metastatic Ovarian or Breast Cancer Treated With Caelyx (Study P05020)
The objective of this trial is to study the management of PPE in participants with metastatic ovarian or breast cancer treated with Caelyx, and determine the frequency of use of pharmacological treatment (preventive or…
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Paresthesia
- Trial name
- NCT00746694
- Volunteers
- 154 people
- Sponsor
- Merck Sharp & Dohme LLC
Pain, Peripheral Neuropathy
MC5-A Scrambler Therapy or TENS Therapy in Treating Patients With Chemotherapy-Induced Peripheral Neuropathy
This randomized clinical trial studies how well MC5-A scrambler therapy or transcutaneous electrical nerve stimulation (TENS) therapy work in treating patients with chemotherapy-induced peripheral neuropathy (a nerve problem that…
- Conditions
- Pain, Peripheral Neuropathy, Tingling
- Trial name
- NCT02722434
- Testing
- Laboratory Biomarker Analysis, MC5-A Scrambler Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Inferior Alveolar Nerve Injury, Neurosensory Disturbance
Comparison of the Results of Biostimulation Treatment of Inferior Alveolar Nerve Injury Using Nd:YAG and Diode Lasers With Different Wavelengths.
Intraoral surgical procedures such as sagittal split osteotomy, dental implant placement, and surgical extraction of third molars are widely performed interventions in oral and maxillofacial surgery.
- Conditions
- Inferior Alveolar Nerve Injury, Neurosensory Disturbance, Paresthesia and Hypoesthesia, Nerve Regeneration
- Trial name
- NCT07416006
- Testing
- Nd:YAG Laser Biostimulation, Diode Laser Biostimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Burning
Dexmedetomidine for Morphine Consumption Reduction (DEXDOR)
The new progresses relative to sedation-analgesia for resuscitation unit lead to perform a light and cooperative sedation as soon as possible in order to decrease the period of mechanical ventilation.
- Trial name
- DEXDOR (NCT02904460)
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Meralgia Paresthetica
Efficacy of Ultrasound-guided Injection of 5% Dextrose for Meralgia Paresthesia
Meralgia paresthetica (MP) is one of the most common peripheral entrapment neuropathies of the lower limbs. It is characterized by paresthesia, pain, tingling, numbness, hypersensitivity, or other abnormal skin sensations on the…
- Trial name
- NCT06251882
- Testing
- injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University People's Hospital
Skin Burns
ST266 in UV-induced Inflammation
This phase II clinical study will include fifteen healthy light skinned adult volunteers. At screening subjects will be given a sunburn test.
- Trial name
- NCT02389777
- Testing
- ST266 immediate, ST266 delayed
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Meralgia Paresthetica, Femoral Neuropathy
Effect of MET on Meralgia Paraesthesia Postpartum "Muscle Energy Technique"
To investigate the effect of muscle energy technique on Femoral meralgia paraesthesia in a postpartum female. BACKGROUND: meralgia paraesthesia is one of the serious disorders in the postpartum female which results in pain and…
- Trial name
- MET (NCT04747119)
- Testing
- muscle energy technique, conventional selected physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Muscle Weakness, Pain, Postoperative
Depo-Medrol on Psoas After LLIF
The goal of this study is to determine the effects of a corticosteroid administered to the psoas muscle following a transpsoas lateral lumbar interbody fusion (LLIF) on postoperative hip flexor weakness and thigh pain and…
- Conditions
- Muscle Weakness, Pain, Postoperative, Paresthesia, Pain, Muscle
- Trial name
- NCT05929755
- Testing
- Depo-Medrol, Gel-Flow NT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Hardeep Singh
Pain, Diabetic Neuropathies
A Research Study of V3381 for the Treatment of Diabetic Peripheral Neuropathic Pain
The objective of this study is to investigate the safety and efficacy of an investigational drug, V3381, for the treatment of diabetic peripheral neuropathic (DPN) pain (pain in one's feet and legs, or even in one's hands and…
- Trial name
- NCT00375960
- Testing
- V3381
- Where
- 6 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Vernalis (R&D) Ltd
Fatigue, Radicular Pain
Effects of Doxycycline on Persistent Symptoms Post-neuroborreliosis
The aim of this randomised, double-blind crossover study was to determine whether Doxycycline has an impact on the persistent symptoms post-neuroborreliosis, through alterations in the immune response and whether such an effect…
- Conditions
- Fatigue, Radicular Pain, Cognitive Dysfunction, Paresthesia
- Trial name
- NCT01205464
- Testing
- Doxycycline
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Linkoeping University
Paresthesia, Total Hip Arthroplasty (THA)
Percussive vs. Gentle Massage for Recovery After Hip Replacement
Many people who have hip replacement surgery through a "bikini incision" on the front of the hip (anterior approach) develop numbness, tingling, burning, or tightness in the front and side of the thigh afterward.
- Conditions
- Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
- Trial name
- NCT07790705
- Testing
- Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Zachary M Ricciardelli
Metastases, Colorectal Neoplasms
Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.
Primary Objective : Compare the risk of occurrence of Grade3-4 cumulative peripheral sensory neuropathy (PSN) relative to cumulative dose of oxaliplatin between treatment group and placebo group.
- Conditions
- Metastases, Colorectal Neoplasms, Colorectal Carcinoma
- Trial name
- NCT00305188
- Testing
- Xaliproden (SR57746A), Oxaliplatin, 5-Fluorouracil
- Where
- 13 sites in United States, Argentina and 11 more
- Volunteers
- 879 people
- Sponsor
- Sanofi
Chronic Pain
A Randomised Pilot Study to Assess Differences in Stimulation Induced Paresthesia Between 2 Spinal Cord Stimulation Systems
12-SMI-2014 is a post-market, randomised, pilot study to identify and rate differences in patient experiences with two different types of Spinal Cord Stimulator devices which are routinely used to treat chronic pain.
- Trial name
- CHARACTER SCS (NCT02250469)
- Testing
- Treatment with the Axium SCS system, Treatment with the Medtronic SCS System
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Abbott Medical Devices
Painful Diabetic Neuropathies
Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy
The purpose of this study is to determine if Engensis (VM202) is safe and effective in treating painful diabetic neuropathy.
- Trial name
- NCT01475786
- Testing
- Low Dose: 16 mg Engensis (VM202), High Dose: 32 mg Engensis (VM202)
- Where
- 17 sites in United States, South Korea
- Volunteers
- 104 people
- Sponsor
- Helixmith Co., Ltd.
Skin Burn
Evaluation of Platelet Rich Plasma in Skin Graft Take for Patients With Post Burn Raw Areas
1. To evaluate the effect of the platelet rich plasma on the take of split thickness skin graft and its early and late results in resurfacing of post burn raw areas. 2.
- Trial name
- NCT05996614
- Testing
- PRP in skin grafts, conventional methods in skin grafts
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Paresthesia, Dysesthesia
Sensory Mapping Following Video-assisted Thoracic Surgery
This is a prospective observational cohort study on changes in sensory mapping.
- Conditions
- Paresthesia, Dysesthesia, Pain
- Trial name
- NCT01375283
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Alveolar Bone Loss, Neurosensory Disorder
Impact of Mandibular Canal Trajectory on Paresthesia After Inferior Alveolar Nerve Lateralization
This prospective cohort study aims to investigate the relationship between mandibular canal trajectory and the duration of postoperative paresthesia in patients undergoing inferior alveolar nerve lateralization.
- Trial name
- NCT05811741
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University