Clinical trials: Parkinson's Disease (Disorder)
Parkinson Disease
Core Stability and Parkinson Disease
Patients with Parkinson's Disease frequently present impaired postural control that leads to loss of stability and increased risk of falls.Core system, includes passive structures of the thoracolumbar spine and pelvis that work…
- Trial name
- NCT03580096
- Testing
- Core stability, Standard intervention
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad de Granada
Parkinson Disease
Cognitive Exercise Therapy Approach (BETY) in Parkinson's Disease
Considering the impact of motor and non-motor findings on movement problems in the disease management of people living with PD, biopsychosocial evaluation and treatment approaches are essential.
- Trial name
- NCT06893120
- Testing
- BETY
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Orkun Tüfekçi
Parkinson Disease, Respiration
Telerehabilitation Based Exercise Training in Parkinson's Patients
Parkinson's disease (PD) is the second most common progressive disease after Alzheimer's disease.It is a progressive, multisystemic and neurodegenerative disease. The prevalence of Parkinson's disease increases with age.
- Conditions
- Parkinson Disease, Respiration, Gait Disorders, Neurologic
- Trial name
- NCT05621642
- Testing
- Breathing exercises, Core stabilization exercises, Balance and strengthening exercises
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Healthy Volunteers
Phase 1 Study of NPT200-11 in Healthy Subjects
The purpose of this study is to determine the safety, tolerability and blood levels of orally administered NPT200-11 in healthy subjects. In addition, the maximally tolerated dose will be determined.
- Trial name
- NCT02606682
- Testing
- NPT200-11
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Neuropore Therapies Inc.
Parkinson Disease
Genetic Study in Young Onset Parkinson's Disease
Parkinson's disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer's disease. It causes motor dysfunctions, such as bradykinesia, resting tremor, rigidity and postural instability.
- Trial name
- NCT01529970
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Lewy Body Dementia, Parkinson Disease
Anti-Diabetic Medications to Fight PD and LBD
The purpose of this study is to test the hypothesis that DPP4 inhibitors and SGLT2 inhibitors are well tolerated and have beneficial neurological effects, specifically for Parkinson's disease and Lewy body dementia.
- Trial name
- NCT06263673
- Testing
- Sitagliptin, Dapagliflozin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic
Deep Brain Stimulation, Parkinson Disease
Apraxia in Parkinson's Disease Patients With Deep Brain Stimulation
Deep brain stimulation (DBS) of the subthalamic nucleus or globus pallidus internus can improve motor symptoms Parkinson's disease (PD).
- Conditions
- Deep Brain Stimulation, Parkinson Disease, Apraxia, Motor
- Trial name
- Apraxia DBS (NCT04725773)
- Testing
- Deep brain stimulation effect on apraxia
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Parkinson Disease
The Effectiveness of LSVT-BIG Training in Improving Balance and Gait in Parkinson's Patients
Parkinson's disease (PD) is a chronic, progressive disease that causes motor and non-motor symptoms due to dopaminergic neuron loss.
- Trial name
- NCT05520541
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Gazi University
Deep Brain Stimulation
SIS Evaluation of the MRI Defined Subthalamic Nucleus*
Retrospective review of images used to target the STN during DBS procedure and ability of the Surgical Information Sciences ("SIS") system to visualize the STN location.
- Trial name
- STN (NCT03907319)
- Testing
- SIS System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Surgical Information Sciences Inc.
Amyotrophic Lateral Sclerosis, Brainstem Stroke
Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit
This project adds to non-invasive BCIs for communication for adults with severe speech and physical impairments due to neurodegenerative diseases.
- Conditions
- Amyotrophic Lateral Sclerosis, Brainstem Stroke, Muscular Dystrophies, Parkinson's Disease and Parkinsonism
- Trial name
- BCI-FIT (NCT04468919)
- Testing
- BCI-FIT multi-modal access, BCI-FIT adaptive signal modeling, BCI-FIT active querying
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
PARKINSON DISEASE (Disorder)
Feasibility of a Community-Based Multimodal Exercise Programme in Parkinson's Disease
This study aims to evaluate the feasibility and preliminary effectiveness of a multimodal, group-based but individualised therapeutic exercise programme for people with Parkinson's disease delivered within a real-world…
- Trial name
- NCT07618728
- Testing
- Exercise Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad Rey Juan Carlos
Parkinson Disease
Neuro-immune Interactome in Parkinson's Disease
This study will be observational and have a prospective case-control longitudinal design. Eligible subjects with idiopathic REM behavior disorder (RBD), Parkinson's disease with RBD, and healthy controls will be recruited.
- Trial name
- NCT07026929
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Yale University
Parkinson's Disease
Nocturnal Parkinson's Disease Symptoms Study Group
To study associate factor of Noctural Parkinson's Disease Symptoms and quality of life in Parkinson's disease patients and caregivers.
- Trial name
- NCT01662427
- Testing
- Questionaire to assess Noctural Parkinson's Disease Symptoms
- Where
- Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Parkinson's Disease
Spinal Cord Stimulation in the Treatment of Parkinson's Disease
Parkinson's disease affects between 100'000 and 150'000 people in France. Drug therapy (L-Dopa and other drugs) is effective to improve motor symptoms but after an initial 'honeymoon period' lasting a few years, motor symptoms…
- Trial name
- STIMUPARK (NCT02381951)
- Testing
- spinal cord stimulation (St Jude Medical)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Alzheimer's Disease, Parkinson's Disease
Evaluation of a Diet in Patients With Senile Dementia
The most common symptoms associated to senile dementia disease are confusion about schedules, hyperactivity... In this sense, these patients have frequently poor nutrition, resulting in malnutrition problems or malnutrition high…
- Conditions
- Alzheimer's Disease, Parkinson's Disease, Senile Dementia
- Trial name
- SUPRESSI (NCT01192529)
- Testing
- Supressi. T-Diet plus Range, High Protein. T-Diet plus Range
- Where
- 3 sites in Spain
- Volunteers
- 184 people
- Sponsor
- Vegenat, S.A.
Covid19, Neurologic Manifestations
Evaluation of Biological Response to SARS-COV2 (COVID-19) in Patients With Pre-existing Neurological Disease or Newly Neurological Symptoms (BIO-COCO-NEUROSCIENCES)
Patients with neurological or psychiatric symptoms or pre-existing disease will be sampled (blood for serum and DNA or saliva for DNA) at inclusion and at M6 (blood) and M12 (blood) depending on their pathology.
- Conditions
- Covid19, Neurologic Manifestations, Psychiatric Manifestations
- Trial name
- NCT04568707
- Testing
- blood sample
- Where
- France
- Volunteers
- 238 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson's Disease
Study to Evaluate the Safety and Efficacy of ESC-derived Dopamine Progenitor Cell Therapy in PD Patients
Indication: Patients who were diagnosed with Parkinson's disease ≥ 5 years ago. Purpose: To find the maximum tolerable dose and evaluate the safety and exploratory efficacy of allogenic embryonic stem cell-derived A9 dopamine…
- Trial name
- NCT05887466
- Testing
- Allogenic embryonic stem cell-derived A9 dopamine progenitor cell (A9-DPC) Low Dose, Allogenic embryonic stem cell-derived A9 dopamine progenitor cell (A9-DPC) High Dose
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- S.Biomedics Co., Ltd.
Parkinson Disease
Trial of Probiotics for Constipation in Parkinson's Disease
This is a double blinded randomised placebo controlled trial to evaluate the efficacy of probiotics in the treatment of constipation in Parkinson's disease.
- Trial name
- NCT03377322
- Testing
- Probiotic Capsule
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- University of Malaya
Parkinson Disease
A Late Phase II Clinical Trial of KDT-3594 in Patients With Parkinson's Disease
This trial is a late phase II, multicenter, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy, safety, and pharmacokinetics of KDT-3594 administered at escalating doses ranging from 0.25…
- Trial name
- NCT06722729
- Testing
- KDT-3594
- Where
- Japan
- Volunteers
- 178 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Parkinson Disease, Dementia
A Study to Evaluate ENT-01 for the Treatment of Parkinson's Disease Dementia
This study will be conducted as a multi-center, open label study in the US. There will be 40 patient to receive the active investigational product.
- Trial name
- NCT03938922
- Testing
- Active Investigational Treatment ENT-01
- Where
- 3 sites in United States
- Sponsor
- Enterin Inc.
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