Clinical trials: Parodontitis
Periodontal Diseases, Rheumatoid Arthritis
Association Between Periodontitis and the Level of Anti-citrullinated Protein Antibodies in Rheumatoid Arthritis
the relationship between rheumatoid arthritis and periodontal disease is crucial and has been explained via a complex interplay of genetic, environmental, and hormonal factors that influence the host immune tolerance leading to…
- Trial name
- NCT05706493
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Misr International University
Periodontitis, Adult, Mouthwash
Evaluation of Coconut Oil Mouth Rinse on Periodontal Parameters
This study was based on testing a new natural mouthwash with coconut oil and xylitol as active agents to a placebo rinse on new periodontal parameters
- Trial name
- NCT07175090
- Testing
- Coconut oil
- Where
- Kosovo
- Volunteers
- 120 people
- Sponsor
- University of Pristina
Periodontitis, Gingivitis
Interleukin-38 Levels in Individuals With Periodontitis
Interleukin (IL)-38 is the newest member of the IL-1 family. It can bind to receptors through various pathways and regulate the formation and function of inflammatory cytokines.
- Conditions
- Periodontitis, Gingivitis, Healthy
- Trial name
- NCT05568290
- Testing
- Saliva, gingival crevicular fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Periodontal Diseases, Coronary Disease
Quantification of Micro-RNA 146-a in Chronic Periodontitis and Coronary Heart Disease Subjects
The expression and quantification of Micro-RNA 146-a, was analyzed in the subgingival plaque samples of generalized chronic periodontitis patients with and without coronary heart disease.
- Trial name
- NCT03721159
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Chronic Periodontitis
Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.
Periodontal disease is an infectious disease resulting in inflammation within supporting tissues of the teeth, progressive attachment loss, and bone loss.
- Trial name
- NCT02121665
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 42 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Periodontitis
AUTOLOGOUS FIBRIN GLUE VERSES 4-0 SILK SUTURES IN PERIODONTAL FLAP CLOSURE
The study is a split mouth study but the interventions for the two different arms will be spaced by a fixed duration in time. Verbal and written consent will be obtained from the patients fulfilling the inclusion and exclusion…
- Trial name
- NCT03792113
- Testing
- Periodontal Flap Surgery, Autologous fibrin glue, 4-0 silk suture
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Periodontal Bone Loss, Chronic Periodontitis
Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
The present study aimed to evaluate the effects of enamel matrix derivatives either alone or combined with autogenous bone graft applied to intrabony defects in chronic periodontitis patients on clinical/radiographic parameters…
- Trial name
- NCT02218515
- Testing
- Open Flap Debridement, EmdogainⓇ(Enamel Matrix Derivative), EmdogainⓇEnamel Matrix Derivative+Autogenous Bone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haner Direskeneli, Prof
Postoperative Pain, Apical Periodontitis
Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical Periodontitis
a randomized clinical study to compare the effect of using low level laser therapy versus calcium hydroxide intra-canal medication on: Incidence and intensity of postoperative pain in patients with symptomatic apical…
- Trial name
- NCT04594317
- Testing
- low level laser therapy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Gingivitis
GFI-1 and Periodontal Disease
Gum disease, including gingivitis and its more advanced form, periodontitis, is a common condition that damages the tissues supporting the teeth.
- Trial name
- NCT07758374
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Periodontal Pocket
Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT
The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis
- Trial name
- NCT06505759
- Testing
- Bromelain gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontal Pocket, Periodontitis
Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual Scalers
Periodontitis is a chronic condition associated with the inflammatory destruction of the periodontal tissues ultimately leading to tooth loss.
- Conditions
- Periodontal Pocket, Periodontitis, Gingival Diseases, Gingival Bleeding
- Trial name
- NCT06351982
- Testing
- Electro Medical Systems AIRFLOW® Prophylaxis Master Device, Hand and ultrasonic scalers and curettes
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intrabony Periodontal Defect
Perforated Collagen Membrane With Nanohydroxyapatite for Intrabony Defects
The ultimate goal of periodontal therapy is the regeneration of periodontal tissues which have been destroyed due to periodontal disease.
- Trial name
- NCT03399279
- Testing
- Open flap debridment, Perforated collagen membrane, Occlusive membrane
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Biomarkers
Accuracy of Host-derived Biomarkers in Diagnosing Symptomatic and Asymptomatic Apical Periodontitis
Apical lesions usually present clinically as a chronic infection, remaining as asymptomatic apical periodontitis(AAP). Because the balance among inflammation and bacteria is a dynamic process, AAP may undergo an acute…
- Trial name
- NCT06187324
- Testing
- biomarkers
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Irreversible Pulpitis, Apical Periodontitis
Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant.
The chief aim of root canal treatment is to reduce the microbial content and prevent further recontamination in the canal. Properly cleaned, shaped and obturated teeth will be having fewer chances of treatment failure.
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Root Canal Infection
- Trial name
- NCT05038059
- Testing
- ethanolic extract of sapindus mukorossi, ethylene diamine tetra acetic acid
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
hsCRP
Association Between Grade(B/C)of Stage III and IV Periodontitis and High Sensitivity C Reactive Protein Level in Serum and Oral Rinse Sample
According to 2017 World Workshop of Periodontology , the level of high sensitivity C reactive protein has been assumed to increase according to the grade of periodontitis, however, specific evidence regarding this is lacking at…
- Trial name
- NCT06997770
- Where
- India
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Periodontitis, Aggressive Periodontitis
Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System
In the present clinical study including chronic, aggressive periodontitis and healthy individuals, the investigators aimed to determine the RANKL, osteoprotegrin (OPG), Interleukin-1 (IL-1β), IL-10, IL-1β levels in gingival…
- Conditions
- Chronic Periodontitis, Aggressive Periodontitis, RANKL/OPG Ratio, Gingival Crevicular Fluid
- Trial name
- NCT02190773
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Peridontal Disease, Dental Anxiety
The Effect of Hypnosis on Periodontal Treatment
Treatment of periodontal diseases relies on the mechanical removal of microbial dental plaque, calculus, and necrotic cementum from root surfaces in both supra- and subgingival areas to control inflammation in periodontal…
- Trial name
- NCT06808373
- Testing
- hypnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Afyonkarahisar Health Sciences University
Periodontitis, Diabetes Mellitus
Adjunctive Hyaluronic Acid Gel in Non-Surgical Periodontal Treatment of Patients With Diabetes Mellitus
The goal of this clinical trial is to evaluate whether the adjunctive use of hyaluronic acid (HA) improves periodontal healing in people with diabetes mellitus and periodontitis.
- Conditions
- Periodontitis, Diabetes Mellitus, Hyaluronic Acid, Oral Microbiota
- Trial name
- NCT07631273
- Testing
- Scaling and root planing, Hyaluronic Acid (HYADENT BG)
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Marmara University
Primary Immune Deficiency Disorder, Periodontitis
Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study
Title: Investigation of neutrophil defects associated with periodontal disease and tooth loss in children. A clinical study. Objectives: The primary objective of this study is: To investigate presence of periodontal disease and…
- Trial name
- GOSH (NCT03069079)
- Testing
- Oral hygiene advice, non surgical periodontal treatment
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Queen Mary University of London
Chronic Periodontitis
Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.
This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions.
- Trial name
- NCT06893107
- Testing
- Intentional Replantation
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Fujairah
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